Search Results - "Willing, A E"

Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats by JIELI CHEN, SANBERG, Paul R, YI LI, LEI WANG, MEI LU, WILLING, Allison E, SANCHEZ-RAMOS, Juan, CHOPP, Michael

“…Human umbilical cord blood cells (HUCBC) are rich in stem and progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain,…”
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Intravenous versus intrastriatal cord blood administration in a rodent model of stroke by Willing, A.E., Lixian, J., Milliken, M., Poulos, S., Zigova, T., Song, S., Hart, C., Sanchez-Ramos, J., Sanberg, P.R.

“…Human umbilical cord blood (hUCB) is a rich source of hematopoietic stem cells that have been used to reconstitute immune cells and blood lineages. Cells from…”
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Cord blood administration induces oligodendrocyte survival through alterations in gene expression by Rowe, D.D, Leonardo, C.C, Hall, A.A, Shahaduzzaman, M.D, Collier, L.A, Willing, A.E, Pennypacker, K.R

“…Abstract Oligodendrocytes (OLs), the predominant cell type found in cerebral white matter, are essential for structural integrity and proper neural signaling…”
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Delayed treatments for stroke influence neuronal death in rat organotypic slice cultures subjected to oxygen glucose deprivation by Hall, A.A, Leonardo, C.C, Collier, L.A, Rowe, D.D, Willing, A.E, Pennypacker, K.R

“…Abstract A major limitation of current stroke therapies is the need to treat candidate patients within 3 h of stroke onset. Human umbilical cord blood cell…”
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Human Umbilical Cord Blood Cells Alter Blood and Spleen Cell Populations After Stroke by Golden, J. E., Shahaduzzaman, M., Wabnitz, A., Green, S., Womble, T. A., Sanberg, P. R., Pennypacker, K. R., Willing, A. E.

“…The human umbilical cord blood (HUCB) mononuclear cell (MNC) fraction is a mixed population of cells that induces functional repair in rodent models of stroke…”
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Gastric distension-induced c-fos expression in catecholaminergic neurons of rat dorsal vagal complex by Willing, A E, Berthoud, H R

“…Functionally specific vagal afferents were stimulated by gastric balloon distension in unanesthetized rats, followed by double c-fos/dopamine beta-hydroxylase…”
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Lack of NF-κB p50 Exacerbates Degeneration of Hippocampal Neurons after Chemical Exposure and Impairs Learning by Kassed, C.A., Willing, A.E., Garbuzova-Davis, S., Sanberg, P.R., Pennypacker, K.R.

“…The roles of activated NF-κB subunits in the CNS remain to be discerned. Members of this family of transcription factors are essential to diverse physiological…”
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The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor by SHAMEKH, R, CAMERON, D. F, WILLING, A. E, SAPORTA, S

“…Neural transplantation is developing as a successful treatment for neurodegenerative diseases such as Parkinson's disease. The human Ntera-2/D1 (NT2) cell line…”
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Monocytes are essential for the neuroprotective effect of human cord blood cells following middle cerebral artery occlusion in rat by Womble, T.A., Green, S., Shahaduzzaman, M., Grieco, J., Sanberg, P.R., Pennypacker, K.R., Willing, A.E.

“…Systemic administration of human umbilical cord blood (HUCB) mononuclear cells (MNC) following middle cerebral artery occlusion (MCAO) in the rat reduces…”
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Do hematopoietic cells exposed to a neurogenic environment mimic properties of endogenous neural precursors? by Walczak, P., Chen, N., Hudson, J.E., Willing, A.E., Garbuzova-Davis, S.N., Song, S., Sanberg, P.R., Sanchez-Ramos, J., Bickford, P.C., Zigova, T.

“…Hematopoietic progenitors are cells, which under challenging experimental conditions can develop unusual phenotypic properties, rather distant from their…”
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Survival of rat or mouse ventral mesencephalon neurons after cotransplantation with rat sertoli cells in the mouse striatum by Shamekh, R, Newcomb, J, Mallery, J, Cassady, C J, Saporta, S, Cameron, D F, Sanberg, P R, Willing, A E

“…Transplanting cells across species (xenotransplantation) for the treatment of Parkinson's disease has been considered an option to alleviate ethical concerns…”
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NF-κB p50 Is Increased in Neurons Surviving Hippocampal Injury by Pennypacker, K.R., Kassed, C.A., Eidizadeh, S., Saporta, S., Sanberg, P.R., Willing, A.E.

“…Signal transduction pathways that lead to the modulation of genes related to survival and repair mechanisms are activated in neurons that survive injury. These…”
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Sertoli cells decrease microglial response and increase engraftment of human hNT neurons in the hemiparkinsonian rat striatum by Willing, A.E, Sudberry, J.J, Othberg, A.I, Saporta, S, Poulos, S.G, Cameron, D.F, Freeman, T.B, Sanberg, P.R

“…Sertoli cells (SCs) provide immune protection and nutritive support to the developing germ cells in the testis. Sertoli cells have also been shown to provide…”
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Green fluorescent protein bone marrow cells express hematopoietic and neural antigens in culture and migrate within the neonatal rat brain by Hudson, J.E., Chen, N., Song, S., Walczak, P., Jendelová, P., Sykova, E., Willing, A.E., Saporta, S., Bickford, P., Sanchez-Ramos, J., Zigova, T.

“…Finding a reliable source of alternative neural stem cells for treatment of various diseases and injuries affecting the central nervous system is a challenge…”
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Lithium Chloride Induces the Expression of Tyrosine Hydroxylase in hNT Neurons by Zigova, Tanja, Willing, Alison E., Tedesco, Erin M., Borlongan, Cesario V., Saporta, Samuel, Snable, Gary L., Sanberg, Paul R.

“…In the present study, several doses of lithium chloride were tested for their ability to induce the expression of tyrosine hydroxylase (TH) in neurons derived…”
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Human umbilical cord blood cells directly suppress ischemic oligodendrocyte cell death by Hall, A.A., Guyer, A.G., Leonardo, C.C., Ajmo Jr, C.T., Collier, L.A., Willing, A.E., Pennypacker, K.R.

“…Previous reports have shown that human umbilical cord blood cells (HUCBCs) administered intravenously 48 hr following middle cerebral artery occlusion reduce…”
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Sertoli cells enhance the survival of co-transplanted dopamine neurons by Willing, Alison E., Othberg, Agneta I., Saporta, Samuel, Anton, Alex, Sinibaldi, Stacy, Poulos, Stephen G., Cameron, Donald F., Freeman, Thomas B., Sanberg, Paul R.

“…One of the major issues in neural transplantation is the low survival rate (<5%) of transplanted dopamine (DA) neurons [3]. Recently it has been shown that it…”
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Induction of presenilins in the rat brain after middle cerebral arterial occlusion by Pennypacker, Keith R, Hernandez, Herman, Benkovic, Stanley, Morgan, David G, Willing, Alison E, Sanberg, Paul R

“…In the present study, we have examined the expression of both presenilins in the rat hippocampus, cortex, striatum, and cerebellum after middle cerebral artery…”
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Behavioral alterations in Lewis rats following two-day continuous 3-nitropropionic acid administration by Newcomb, J D, Brown, W D, Rodriguez, A I, Garbuzova-Davis, S, Saporta, S, Sanberg, P R, Willing, A E

“…The mitochondrial toxin, 3-nitropropionic acid (3-NP), produces motor dysfunction and striatal atrophy in rats. However, rat strain and method of…”
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Expression of fos-related antigen-2 in rat hippocampus after middle cerebral arterial occlusion by Pennypacker, Keith R, Eidizadeh, Shabnam, Kassed, Cheryl A, O'Callaghan, James P, Sanberg, Paul R, Willing, Alison E

“…AP-1 transcription factors have been shown to be induced in the brain after ischemic injury. However, their roles in neuronal survival or death have yet to be…”
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