Search Results - "Williamson, Jill"
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Myelin Dynamics Throughout Life: An Ever-Changing Landscape?
Published in Frontiers in cellular neuroscience (19-11-2018)“…Myelin sheaths speed up impulse propagation along the axons of neurons without the need for increasing axon diameter. Subsequently, myelin (which is made by…”
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C−H Functionalization of Commodity Polymers
Published in Angewandte Chemie International Edition (24-06-2019)“…Synthetic manipulation of polymer substrates is one of the oldest and most reliable methods to increase the functional diversity of soft materials. Modifying…”
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New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Published in Nature neuroscience (01-04-2022)“…Oligodendrocytes that survive demyelination can remyelinate, including in multiple sclerosis (MS), but how they do so is unclear. In this study, using…”
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Regioselective C−H Xanthylation as a Platform for Polyolefin Functionalization
Published in Angewandte Chemie International Edition (22-05-2018)“…Polyolefins that contain polar functional groups are important materials for next‐generation lightweight engineering thermoplastics. Post‐polymerization…”
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Chemo- and Regioselective Functionalization of Isotactic Polypropylene: A Mechanistic and Structure–Property Study
Published in Journal of the American Chemical Society (14-08-2019)“…Polyolefins represent a high-volume class of polymers prized for their attractive thermomechanical properties, but the lack of chemical functionality on…”
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An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination
Published in eLife (06-07-2018)“…Myelinating oligodendrocytes are essential for central nervous system (CNS) formation and function. Their disruption is implicated in numerous…”
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Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
Published in Current biology (13-09-2021)“…Myelination of axons by oligodendrocytes enables fast saltatory conduction. Oligodendrocytes are responsive to neuronal activity, which has been shown to…”
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Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand
Published in Current biology (23-04-2018)“…The correct targeting of myelin is essential for nervous system formation and function. Oligodendrocytes in the CNS myelinate some axons, but not others, and…”
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Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study
Published in JNCI : Journal of the National Cancer Institute (02-03-2011)“…Genome-wide association studies have identified several common genetic variants associated with breast cancer risk. It is likely, however, that a substantial…”
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Manipulating Neuronal Activity in the Developing Zebrafish Spinal Cord to Investigate Adaptive Myelination
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…In the central nervous system, oligodendrocyte-lineage cells and myelination can adapt to physiological brain activity. Since myelin can in turn regulate…”
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease
Published in BMJ open (07-07-2022)“…IntroductionMotor neuron disease (MND) is a rapidly fatal neurodegenerative disease. Despite decades of research and clinical trials there remains no cure and…”
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A flow injection analysis system for monitoring silver (I) ion and iodine residuals in recycled water from recovery systems used for spaceflight
Published in Analytica chimica acta (20-08-2013)“…A device for on-line monitoring of the water disinfectants silver (I) ion or iodine in recycled water is presented. Simply change the reagents and the sample…”
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13
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective
Published in Brain communications (01-10-2021)“…Abstract Amyotrophic lateral sclerosis is a progressive and devastating neurodegenerative disease. Despite decades of clinical trials, effective…”
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Hepatocytes from non-hepatic adult stem cells
Published in Nature (London) (20-07-2000)“…Stem cells are undifferentiated long-lived cells that are capable of many rounds of division. Here we show that adult human liver cells can be derived from…”
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Microbial isolation and characterization from two flex lines from the urine processor assembly onboard the International Space Station
Published in Biofilm (01-12-2023)“…Urine, humidity condensate, and other sources of non-potable water are processed onboard the International Space Station (ISS) by the Water Recovery System…”
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Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei
Published in Journal of cell science (01-05-2000)“…The large-scale chromatin organization of the major histocompatibility complex and other regions of chromosome 6 was studied by three-dimensional image…”
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17
Regioselective C−H Xanthylation as a Platform for Polyolefin Functionalization
Published in Angewandte Chemie (22-05-2018)“…Polyolefins that contain polar functional groups are important materials for next‐generation lightweight engineering thermoplastics. Post‐polymerization…”
Get full text
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18
Mutation Cluster Region, Association Between Germline and Somatic Mutations and Genotype-Phenotype Correlation in Upper Gastrointestinal Familial Adenomatous Polyposis
Published in The American journal of pathology (01-06-2002)“…Studies of adenomatous polyposis coli ( APC ) mutations in familial adenomatous polyposis (FAP) have focused on large bowel disease. It has been found that: 1)…”
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C‐H‐Funktionalisierung von Standardpolymeren
Published in Angewandte Chemie (24-06-2019)“…Die präparative Modifizierung von Polymersubstraten ist eine der ältesten und zuverlässigsten Methoden zur Erhöhung der funktionellen Vielfalt von weichen…”
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Replication Timing Profile Reflects the Distinct Functional and Genomic Features of the MHC Class II Region
Published in Cell cycle (Georgetown, Tex.) (01-10-2007)“…The timing of DNA replication generally correlates with transcription, gene density and sequence composition. How is the timing affected if a genomic region…”
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