Search Results - "Williamson, James D"

The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis by Williamson, James D., Sadofsky, Laura R., Hart, Simon P.

“…ABSTRACTIdiopathic pulmonary fibrosis (IPF) is a devastating disease of unknown etiology, for which there is no curative pharmacological therapy. Bleomycin, an…”
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A report from the NIHR UK working group on remote trial delivery for the COVID-19 pandemic and beyond by Masoli, Jane A H, Down, Kim, Nestor, Gary, Hudson, Sharon, O'Brien, John T, Williamson, James D, Young, Carolyn A, Carroll, Camille

“…Prior to the COVID-19 pandemic, the majority of clinical trial activity took place face to face within clinical or research units. The COVID-19 pandemic…”
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Clostridium difficile-Associated Diarrhea: Epidemiological Data from Western Australia Associated with a Modified Antibiotic Policy by Thomas, Claudia, Stevenson, Mark, Williamson, D. James, Riley, Thomas V.

“…The incidence of Clostridium difficile-associated diarrhea (CDAD) has increased dramatically in hospitals worldwide during the past 2 decades. In Western…”
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The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration? by Hayman, Yvette A, Sadofsky, Laura R, Williamson, James D, Hart, Simon P, Morice, Alyn H

“…Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid-laden…”
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While K-ras Is Essential for Mouse Development, Expression of the K-ras 4A Splice Variant Is Dispensable by Plowman, Sarah J, Williamson, D James, O'Sullivan, Maureen J, Doig, Jennifer, Ritchie, Ann-Marie, Harrison, David J, Melton, David W, Arends, Mark J, Hooper, Martin L, Patek, Charles E

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Early re‐presentation to hospital after discharge from an acute medical unit: perspectives of older patients, their family caregivers and health professionals by Slatyer, Susan, Toye, Christine, Popescu, Aurora, Young, Jeanne, Matthews, Anne, Hill, Andrew, Williamson, D James

“…Aims and objectives To explore the perceptions of older patients who re‐presented to hospital within 28 days of discharge from an acute medical unit (AMU),…”
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Continuous Cough Monitoring Using Ambient Sound Recording During Convalescence from a COPD Exacerbation by Crooks, Michael G., den Brinker, Albertus, Hayman, Yvette, Williamson, James D., Innes, Andrew, Wright, Caroline E., Hill, Peter, Morice, Alyn H.

“…Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases…”
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Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin by Williamson, James D., Sadofsky, Laura R., Crooks, Michael G., Greenman, John, Hart, Simon P.

“…Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell…”
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Characterisation of a New Human Alveolar Macrophage-Like Cell Line (Daisy) by Sadofsky, Laura R., Hayman, Yvette A., Vance, Jesse, Cervantes, Jorge L., Fraser, Simon D., Wilkinson, Holly N., Williamson, James D., Hart, Simon P., Morice, Alyn H.

“…Purpose There is currently no true macrophage cell line and in vitro experiments requiring these cells currently require mitogenic stimulation of a macrophage…”
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Hemodynamic effects of bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension by WILLIAMSON, D. J, WALLMAN, L. L, JONES, R, KEOGH, A. M, SCROOPE, F, PENNY, R, WEBER, C, MACDONALD, P. S

“…Few treatments are available for isolated pulmonary hypertension (PHT), which has a high morbidity and mortality. This trial was designed to assess the…”
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Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage by Lang, R A, Metcalf, D, Cuthbertson, R A, Lyons, I, Stanley, E, Kelso, A, Kannourakis, G, Williamson, D J, Klintworth, G K, Gonda, T J

“…Transgenic mice carrying the murine granulocyte-macrophage colony stimulating factor (GM-CSF) gene expressed from a retroviral promoter exhibit elevated levels…”
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Update on scleroderma by Williamson, D J

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Murine eosinophil differentiation factor. An eosinophil-specific colony-stimulating factor with activity for human cells by Lopez, A F, Begley, C G, Williamson, D J, Warren, D J, Vadas, M A, Sanderson, C J

“…A purified murine lymphokine, eosinophil differentiation factor (EDF), was found to be a selective stimulus for the clonal proliferation and differentiation of…”
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While K-ras Is Essential for MouseDevelopment, Expression of the K-ras 4A Splice VariantIsDispensable by Plowman, Sarah J., Williamson, D. James, O'Sullivan, Maureen J., Doig, Jennifer, Ritchie, Ann-Marie, Harrison, David J., Melton, David W., Arends, Mark J., Hooper, Martin L., Patek, Charles E.

“…In mammals, the three classical ras genes encode four highly homologous proteins, N-Ras, H-Ras, and the isoforms K-Ras 4A and 4B. Previous studies have shown…”
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Detection of colony-stimulating factor messenger RNA in single T cells by in situ hybridization by Williamson, D J, Owens, T, Pearse, M

“…In situ hybridization has been used to study the accumulation of colony-stimulating factor (CSF) mRNA in single cells of a T lymphocyte clone (E9.D4) following…”
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A comparison of eosinophil-activating factor (EAF) with other monokines and lymphokines by Thorne, K J, Richardson, B A, Taverne, J, Williamson, D J, Vadas, M A, Butterworth, A E

“…Monocytes from moderately eosinophilic individuals secrete material that enhances the cytotoxic activity of eosinophils against antibody-coated schistosomula…”
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Enhancement of neutrophil-mediated phagocytosis by human granulocyte-macrophage colony-stimulating factor demonstrated using a novel mathematical model by Williamson, D J, Brown, T C

“…A mathematical model is presented which may be applied to describe and analyse data from microscopic phagocytosis assays. The method has been used to…”
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Colony-stimulating factors in the pathogenesis and treatment of disease by Williamson, D. J., Begley, C. G.

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Learning Logo: What Is Really Learned? by Ginther, Dean W, Williamson, James D

“…Review of existing research on the general cognitive outcomes of Logo training concludes there is little data-based or empirical evidence on the effects of…”
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Evidence for local synthesis of antibodies to denatured collagen in the synovium in rheumatoid arthritis by Rowley, M J, Williamson, D J, Mackay, I R

“…Synovial fluid samples from 36 patients with rheumatoid arthritis (RA) and 31 patients with other articular diseases (OAD) were examined for the presence of…”
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