Search Results - "Williams, S. B"

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  1. 1

    Developing a Tanshinone IIA Memetic by Targeting MIOS to Regulate mTORC1 and Autophagy in Glioblastoma by Shinhmar, Sonia, Schaf, Judith, Lloyd Jones, Katie, Pardo, Olivier E, Beesley, Philip, Williams, Robin S B

    “…Tanshinone IIA (T2A) is a bioactive compound that provides promise in the treatment of glioblastoma multiforme (GBM), with a range of molecular mechanisms…”
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  2. 2

    Magnetic-field-assisted terahertz quantum cascade laser operating up to 225 K by Smirnov, D, Wade, A, Fedorov, G, Kumar, S, Williams, B. S, Hu, Q, Reno, J. L

    Published in Nature photonics (01-01-2009)
    “…Advances in semiconductor bandgap engineering have resulted in the recent development of the terahertz quantum cascade laser 1 . These compact optoelectronic…”
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  3. 3

    Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders by Augustin, Katrin, Khabbush, Aziza, Williams, Sophie, Eaton, Simon, Orford, Michael, Cross, J Helen, Heales, Simon J R, Walker, Matthew C, Williams, Robin S B

    Published in Lancet neurology (01-01-2018)
    “…High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this…”
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  4. 4

    Topography, substratum and benthic macrofaunal relationships on a tropical mesophotic shelf margin, central Great Barrier Reef, Australia by Bridge, T. C. L, Done, T. J, Beaman, R. J, Friedman, A, Williams, S. B, Pizarro, O, Webster, J. M

    Published in Coral reefs (01-03-2011)
    “…Habitats and ecological communities occurring in the mesophotic region of the central Great Barrier Reef (GBR), Australia, were investigated using autonomous…”
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  5. 5

    Mitochondrial calcium uptake by Williams, George S. B., Boyman, Liron, Chikando, Aristide C., Khairallah, Ramzi J., Lederer, W. J.

    “…Calcium (Ca²⁺) uptake into the mitochondrial matrix is critically important to cellular function. As a regulator of matrix Ca²⁺ levels, this flux influences…”
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  6. 6

    A common mechanism of action for three mood-stabilizing drugs by Mudge, Anne W, Williams, Robin S. B, Cheng, Lili, Harwood, Adrian J

    Published in Nature (London) (16-05-2002)
    “…Lithium, carbamazepine and valproic acid are effective mood-stabilizing treatments for bipolar affective disorder. The molecular mechanisms underlying the…”
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  7. 7

    Environment-wide association study to comprehensively test and validate associations between nutrition and lifestyle factors and testosterone deficiency: NHANES 1988–1994 and 1999–2004 by Lopez, D. S., Wulaningsih, W., Tsilidis, K. K., Baillargeon, J., Williams, S. B., Urban, R., Rohrmann, S.

    Published in Hormones (Athens, Greece) (01-06-2020)
    “…Purpose Testosterone (T) plays an important role in men’s health and its deficiency is linked with poorer health. However, the role of nutritional and…”
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  8. 8

    Stereo-imaging AUV detects trends in sea urchin abundance on deep overgrazed reefs by Ling, S. D., Mahon, I., Marzloff, M. P., Pizarro, O., Johnson, C. R., Williams, S. B.

    Published in Limnology and oceanography, methods (01-05-2016)
    “…Remote underwater vehicles are cutting‐edge tools for mapping benthic habitats, yet their reliability for detecting patterns in abundance of benthic species…”
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  9. 9

    Enhanced Sestrin expression through Tanshinone 2A treatment improves PI3K-dependent inhibition of glioma growth by Schaf, Judith, Shinhmar, Sonia, Zeng, Qingyu, Pardo, Olivier E., Beesley, Philip, Syed, Nelofer, Williams, Robin S. B.

    Published in Cell death discovery (19-05-2023)
    “…Glioblastomas are a highly aggressive cancer type which respond poorly to current pharmaceutical treatments, thus novel therapeutic approaches need to be…”
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  10. 10

    Functional anatomy and muscle moment arms of the pelvic limb of an elite sprinting athlete: the racing greyhound (Canis familiaris) by Williams, S. B., Wilson, A. M., Rhodes, L., Andrews, J., Payne, R. C.

    Published in Journal of anatomy (01-10-2008)
    “…We provide quantitative anatomical data on the muscle–tendon architecture and geometry of the pelvic limb of an elite sprint athlete, the racing greyhound…”
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  11. 11

    Functional anatomy and muscle moment arms of the thoracic limb of an elite sprinting athlete: the racing greyhound (Canis familiaris) by Williams, S. B., Wilson, A. M., Daynes, J., Peckham, K., Payne, R. C.

    Published in Journal of anatomy (01-10-2008)
    “…We provide quantitative muscle–tendon architecture and geometry data for the racing greyhound thoracic limb. Muscle mass, belly length, fascicle lengths,…”
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  12. 12

    Exploring the mechanical basis for acceleration: pelvic limb locomotor function during accelerations in racing greyhounds (Canis familiaris) by Williams, S B, Usherwood, J R, Jespers, K, Channon, A J, Wilson, A M

    Published in Journal of experimental biology (15-02-2009)
    “…Animals in their natural environments are confronted with a regular need to perform rapid accelerations (for example when escaping from predators or chasing…”
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  13. 13

    CikA, a Bacteriophytochrome That Resets the Cyanobacterial Circadian Clock by SCHMITZ, O, KATAYAMA, M, WILLIAMS, S. B, KONDO, T, GOLDEN, S. S

    “…The circadian oscillator of the cyanobacterium Synechococcus elongatus, like those in eukaryotes, is entrained by environmental cues. Inactivation of the gene…”
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  14. 14

    RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense by Riyahi, Tanja Y, Frese, Frederike, Steinert, Michael, Omosigho, Napoleon N, Glöckner, Gernot, Eichinger, Ludwig, Orabi, Benoit, Williams, Robin S B, Noegel, Angelika A

    Published in PloS one (02-11-2011)
    “…RpkA (Receptor phosphatidylinositol kinase A) is an unusual seven-helix transmembrane protein of Dictyostelium discoideum with a G protein coupled receptor…”
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  15. 15

    Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function by Sharma, Devdutt, Otto, Grant, Warren, Eleanor C., Beesley, Philip, King, Jason S., Williams, Robin S. B.

    Published in Autophagy (03-08-2019)
    “…Mutations in the γ-secretase complex are strongly associated with familial Alzheimer disease. Both proteolytic and non-proteolytic functions for the…”
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  16. 16

    Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes by King, Jason, Keim, Melanie, Teo, Regina, Weening, Karin E, Kapur, Mridu, McQuillan, Karina, Ryves, Jonathan, Rogers, Ben, Dalton, Emma, Williams, Robin S B, Harwood, Adrian J

    Published in PloS one (17-06-2010)
    “…Lithium (Li(+)) is a common treatment for bipolar mood disorder, a major psychiatric illness with a lifetime prevalence of more than 1%. Risk of bipolar…”
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  17. 17

    Antimicrobial activity of extracts from macroalgae Ulva lactuca against clinically important Staphylococci is impacted by lunar phase of macroalgae harvest by Deveau, A.M., Miller‐Hope, Z., Lloyd, E., Williams, B.S., Bolduc, C., Meader, J.M., Weiss, F., Burkholder, K.M.

    Published in Letters in applied microbiology (01-05-2016)
    “…Staphylococcus aureus is a common human bacterial pathogen that causes skin and soft tissue infections. Methicillin‐resistant Staph. aureus (MRSA) are…”
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  18. 18

    Terahertz heterodyne receiver based on a quantum cascade laser and a superconducting bolometer by Gao, J. R., Hovenier, J. N., Yang, Z. Q., Baselmans, J. J. A., Baryshev, A., Hajenius, M., Klapwijk, T. M., Adam, A. J. L., Klaassen, T. O., Williams, B. S., Kumar, S., Hu, Q., Reno, J. L.

    Published in Applied physics letters (13-06-2005)
    “…We report the first demonstration of an all solid-state heterodyne receiver that can be used for high-resolution spectroscopy above 2 THz suitable for…”
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  19. 19

    Effect of doping concentration on the performance of terahertz quantum-cascade lasers by Liu, H. C., Wächter, M., Ban, D., Wasilewski, Z. R., Buchanan, M., Aers, G. C., Cao, J. C., Feng, S. L., Williams, B. S., Hu, Q.

    Published in Applied physics letters (03-10-2005)
    “…We characterized a set of terahertz quantum-cascade lasers with identical device parameters except for the doping concentration. The δ-doping density was…”
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  20. 20

    Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum by Kelly, Elizabeth, Sharma, Devdutt, Wilkinson, Christopher J, Williams, Robin S B

    Published in Disease models & mechanisms (01-09-2018)
    “…Valproic acid (VPA) provides a common treatment for both epilepsy and bipolar disorder; however, common cellular mechanisms relating to both disorders have yet…”
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