Search Results - "Williams, Nana Aba O"

Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts by Masdeu, Carme, Gómez, Elena, Williams, Nana Aba O., Lavilla, Rodolfo

“…Double agent: The insertion of two isocyanide molecules into the dihydropyridine ring in the presence of iodine results in the formation of a benzimidazole…”
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Tyrosinase activated melanoma prodrugs by Jawaid, Samaila, Khan, Tariq H, Osborn, Helen M I, Williams, Nana Aba O

“…Metastatic malignant melanoma remains a highly aggressive form of skin cancer for which no reliable methods for treatment exist. Given the increasing incidence…”
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Synthesis and Evaluation of Novel Boron-Containing Complexes of Potential Use for the Selective Treatment of Malignant Melanoma by Bonjoch, Josep, Drew, Michael G. B, González, Asensio, Greco, Francesca, Jawaid, Samaila, Osborn, Helen M. I, Williams, Nana Aba O, Yaqoob, Parveen

“…Boron-containing complexes that have the potential to irreversibly accumulate in melanoma cells have been prepared by reaction of amino acids with…”
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Isocyanide Addition to Pyridinium Salts. Efficient Entry into Substituted Nicotinonitrile Derivatives by Williams, Nana Aba O, Masdeu, Carme, Díaz, José Luis, Lavilla, Rodolfo

“…The addition of isocyanides to pyridinium salts is studied. The process takes place efficiently when a carboxamido group is present in the 3 position of the…”
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New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT) by Knaggs, Sarah, Malkin, Hugh, Osborn, Helen M I, Williams, Nana Aba O, Yaqoob, Parveen

“…Two novel tyrosinase mediated drug delivery pathways have been investigated for the selective delivery of cytotoxic units to melanocytes from urea and thiourea…”
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Development of Tyrosinase Labile Protecting Groups for Amines by Osborn, Helen M. I, Williams, Nana Aba O

“…The development of two novel protecting groups for amines is described. Thus, a range of amines have been converted to ureas, and the deprotection of these…”
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Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts by Masdeu, Carme, Gómez, Elena, Williams, Nana Aba O., Lavilla, Rodolfo

“…Doppelter Einsatz: Die Insertion von zwei Isocyanidmolekülen in einen Dihydropyridinring führt in Gegenwart von Iod zu einer Benzimidazoleinheit (siehe…”
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Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts by Masdeu, Carme, Gómez, Elena, Williams, Nana Aba O., Lavilla, Rodolfo

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