Search Results - "Williams, Mary C"

Alveolar type I cells: molecular phenotype and development by Williams, Mary C

“…Understanding of the functions and regulation of the phenotype of the alveolar type I epithelial cell has lagged behind studies of its neighbor the type II…”
Get full text

Serines in the Intracellular Tail of Podoplanin (PDPN) Regulate Cell Motility by Krishnan, Harini, Ochoa-Alvarez, Jhon A., Shen, Yongquan, Nevel, Evan, Lakshminarayanan, Meenakshi, Williams, Mary C., Ramirez, Maria I., Miller, W.Todd, Goldberg, Gary S.

“…Podoplanin (PDPN) is a transmembrane receptor that affects the activities of Rho, ezrin, and other proteins to promote tumor cell motility, invasion, and…”
Get full text

Epigenetic Mechanisms Modulate Thyroid Transcription Factor 1-mediated Transcription of the Surfactant Protein B Gene by Cao, Yuxia, Vo, Tiffany, Millien, Guetchyn, Tagne, Jean-Bosco, Kotton, Darrell, Mason, Robert J., Williams, Mary C., Ramirez, Maria I.

“…Epigenetic regulation of transcription plays an important role in cell-specific gene expression by altering chromatin structure and access of transcriptional…”
Get full text

Key developmental regulators change during hyperoxia-induced injury and recovery in adult mouse lung by Pogach, Melanie S., Cao, Yuxia, Millien, Guetchyn, Ramirez, Maria I., Williams, Mary C.

“…Developmentally important genes have recently been linked to tissue regeneration and epithelial cell repair in neonatal and adult animals in several organs,…”
Get full text

Extrarenal expression of 25-hydroxyvitamin D3-1α-Hydroxylase by ZEHNDER, Daniel, BLAND, Rosemary, WILLIAMS, Mary C, MCNINCH, Robert W, HOWIE, Alexander J, STEWART, Paul M, HEWISON, Martin

Get full text

Angiotensin converting enzyme 2 is primarily epithelial and is developmentally regulated in the mouse lung by Wiener, Renda Soylemez, Cao, Yu Xia, Hinds, Anne, Ramirez, Maria I., Williams, Mary C.

“…Angiotensin converting enzyme (ACE) 2 is a carboxypeptidase that shares 42% amino acid homology with ACE. Little is known about the regulation or pattern of…”
Get full text

Synthesis of 1,25-dihydroxyvitamin D3 by human endothelial cells is regulated by inflammatory cytokines: A novel autocrine determinant of vascular cell adhesion by ZEHNDER, Daniel, BLAND, Rosemary, CHANA, Ravinder S, WHEELER, David C, HOWIE, Alexander J, WILLIAMS, Mary C, STEWART, Paul M, HEWISON, Martin

Get full text

ETS1 regulates Twist1 transcription in a KrasG12D/Lkb1−/− metastatic lung tumor model of non-small cell lung cancer by Millien, Guetchyn, Cao, Yuxia, O’Hara, Carl J., Tagne, Jean-Bosco, Hinds, Anne, Williams, Mary C., Ramirez, Maria I., Kathuria, Hasmeena

“…Distinct members of the Ets family of transcription factors act as positive or negative regulators of genes involved in cellular proliferation, development,…”
Get full text

Bone marrow-derived cells as progenitors of lung alveolar epithelium by Kotton, D N, Ma, B Y, Cardoso, W V, Sanderson, E A, Summer, R S, Williams, M C, Fine, A

“…We assessed the capacity of plastic-adherent cultured bone marrow cells to serve as precursors of differentiated parenchymal cells of the lung. By…”
Get full text

T1α, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth by Ramirez, Maria I, Millien, Guetchyn, Hinds, Anne, Cao, YuXia, Seldin, David C, Williams, Mary C

“…T1α, a differentiation gene of lung alveolar epithelial type I cells, is developmentally regulated and encodes an apical membrane protein of unknown function…”
Get full text

The Red journal at 25. A perspective from the founding editors by Senior, Robert M, Brody, Jerome S, Williams, Mary C

“…[...]was what to call the new journal. [...]we wonder:…”
Get full text

Increased PEA3/E1AF and decreased Net/Elk-3, both ETS proteins, characterize human NSCLC progression and regulate caveolin-1 transcription in Calu-1 and NCI-H23 NSCLC cell lines by Sloan, Karin A., Marquez, Hector A., Li, Jun, Cao, Yuxia, Hinds, Anne, O'Hara, Carl J., Kathuria, Satinder, Ramirez, Maria I., Williams, Mary C., Kathuria, Hasmeena

“…Caveolin-1 protein has been called a ‘conditional tumor suppressor’ because it can either suppress or enhance tumor progression depending on cellular context…”
Get full text

ERM is expressed by alveolar epithelial cells in adult mouse lung and regulates caveolin-1 transcription in mouse lung epithelial cell lines by Kathuria, Hasmeena, Cao, YuXia, Hinds, Anne, Ramirez, Maria I., Williams, Mary C.

“…We previously identified an Ets cis‐element in the mouse caveolin‐1 promoter that is selectively activated in lung epithelial (E10), but not lung endothelial…”
Get full text

Transcription of the caveolin-1 gene is differentially regulated in lung type I epithelial and endothelial cell lines. A role for ETS proteins in epithelial cell expression by Kathuria, Hasmeena, Cao, Yuxia X, Ramirez, Maria I, Williams, Mary C

“…In the lung, caveolin-1 is expressed in both type I alveolar epithelial and endothelial cells where it is hypothesized to modulate molecular signaling…”
Get full text

Alterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac development by Millien, Guetchyn, Spira, Avrum, Hinds, Anne, Wang, Junling, Williams, Mary C, Ramirez, Maria I

“…Development of lung alveolar sacs of normal structure and size at late gestation is necessary for the gas exchange process that sustains respiration at birth…”
Get full text

Enhanced binding of Sp1/Sp3 transcription factors mediates the hyperoxia-induced increased expression of the lung type I cell gene T1α by Cao, Yu-Xia, Ramirez, Maria I., Williams, Mary C.

“…The transcription factor Sp1 plays an important regulatory role in transactivation of the lung type I cell differentiation gene T1α. Like other lung cells,…”
Get full text

Fas expression in pulmonary alveolar type II cells by Fine, A, Anderson, N L, Rothstein, T L, Williams, M C, Gochuico, B R

“…Fas, a type I membrane receptor protein, transduces a signal culminating in apoptosis after binding to the Fas ligand. Information regarding the expression of…”
Get full text

The α-Isoform of Caveolin-1 Is a Marker of Vasculogenesis in Early Lung Development by Ramirez, Maria I., Pollack, Lee, Millien, Guetchyn, Cao, Yu Xia, Hinds, Anne, Williams, Mary C.

“…Caveolin-1 is a scaffolding protein component of caveolae, membrane invaginations involved in endocytosis, signal transduction, trans- and intracellular…”
Get full text

Transcription of the Caveolin-1 Gene Is Differentially Regulated in Lung Type I Epithelial and Endothelial Cell Lines by Kathuria, Hasmeena, Cao, Yuxia X., Ramirez, Maria I., Williams, Mary C.

“…In the lung, caveolin-1 is expressed in both type I alveolar epithelial and endothelial cells where it is hypothesized to modulate molecular signaling…”
Get full text

Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C by Williams, M C, Hawgood, S, Hamilton, R L

“…Pulmonary surfactant phospholipids may assume several different structures including tubular myelin, unilamellar and multilamellar vesicles, and others. These…”
Get more information