Search Results - "Williams, Lyda"
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Animal models of in utero exposure to a high fat diet: A review
Published in Biochimica et biophysica acta (01-03-2014)“…The incidence of metabolic disease, including type 2 diabetes and obesity, has increased to epidemic levels in recent years. A growing body of evidence…”
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Journal Article -
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Minireview: Epigenetic Programming of Diabetes and Obesity: Animal Models
Published in Endocrinology (Philadelphia) (01-03-2012)“…A growing body of evidence suggests that the intrauterine (IU) environment has a significant and lasting effect on the long-term health of the growing fetus…”
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Journal Article Book Review -
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Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice
Published in Diabetes (New York, N.Y.) (01-08-2020)“…An adverse maternal in utero and lactation environment can program offspring for increased risk for metabolic disease. The aim of this study was to determine…”
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Journal Article -
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Shared effects of genetic and intrauterine and perinatal environment on the development of metabolic syndrome
Published in PloS one (17-05-2013)“…Genetic and environmental factors, including the in utero environment, contribute to Metabolic Syndrome. Exposure to high fat diet exposure in utero and…”
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Journal Article -
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N-Acetylcysteine Resolves Placental Inflammatory-Vasculopathic Changes in Mice Consuming a High-Fat Diet
Published in The American journal of pathology (01-11-2019)“…The mechanism by which poor maternal nutrition can affect the long-term health of offspring is poorly understood. In mice, we previously found that maternal…”
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Journal Article -
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Treatment of obesity with extension of sleep duration: a randomized, prospective, controlled trial
Published in Clinical trials (London, England) (01-06-2010)“…Background The prevalence of chronic sleep deprivation is increasing in modern societies with negative health consequences. Recently, an association between…”
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Journal Article -
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DNA hypermethylation of CD3+ T cells from cord blood of infants exposed to intrauterine growth restriction
Published in Diabetologia (01-08-2016)“…Aims/hypothesis Intrauterine growth restriction (IUGR) is associated with increased susceptibility to obesity, metabolic syndrome and type 2 diabetes. Although…”
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Journal Article -
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DNA hypermethylation of CD3 super(+) T cells from cord blood of infants exposed to intrauterine growth restriction
Published in Diabetologia (01-08-2016)“…Intrauterine growth restriction (IUGR) is associated with increased susceptibility to obesity, metabolic syndrome and type 2 diabetes. Although the mechanisms…”
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Journal Article -
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DNA hypermethylation of CD3^sup +^ T cells from cord blood of infants exposed to intrauterine growth restriction
Published in Diabetologia (01-08-2016)“…Aims/hypothesis Intrauterine growth restriction (IUGR) is associated with increased susceptibility to obesity, metabolic syndrome and type 2 diabetes. Although…”
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Journal Article -
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High post-natal mortality associated with defects in lung maturation and reduced adiposity in mice with gestational exposure to high fat and N-acetylcysteine
Published in Research in veterinary science (01-10-2017)“…Studies have demonstrated that maternal consumption of a high fat diet (HFD) increases offspring susceptibility to metabolic disease. This study was initiated…”
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Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity
Published in Systems biology in reproductive medicine (03-07-2020)Get full text
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Critical periods of increased fetal vulnerability to a maternal high fat diet
Published in Reproductive biology and endocrinology (18-08-2014)“…Fetal adaptations to high fat (HF) diet in utero (IU) that may predispose to Metabolic Syndrome (MetS) in adulthood include changes in fetal hepatic gene…”
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Journal Article -
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In the beginning: Insight into parental influence on offspring metabolic disease susceptibility in mice and humans
Published 01-01-2017“…The increases in type 2 diabetes (T2DM) and obesity cannot be explained solely by lifestyle and genetic factors. Recent evidence suggests alterations to the…”
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Dissertation -
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Effects of genetics and in utero diet on murine pancreatic development
Published in Journal of endocrinology (01-08-2014)“…Intrauterine (IU) malnutrition could alter pancreatic development. In this study, we describe the effects of high-fat diet (HFD) during pregnancy on fetal…”
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Journal Article -
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Shared Effects of Genetic and Intrauterine and Perinatal Environment on the Development of Metabolic Syndrome. e63021
Published in PloS one (01-05-2013)“…Genetic and environmental factors, including the in utero environment, contribute to Metabolic Syndrome. Exposure to high fat diet exposure in utero and…”
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Journal Article -
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Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity
Published in Systems Biology in Reproductive Medicine (03-07-2020)“…Obesity, known to cause a systemic elevation in monocyte chemotactic protein-1 (MCP-1), adversely affects normal ovarian function. The aim of this study was to…”
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