Search Results - "Williams, Lucy H."

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    Widespread transcriptional pausing and elongation control at enhancers by Henriques, Telmo, Scruggs, Benjamin S, Inouye, Michiko O, Muse, Ginger W, Williams, Lucy H, Burkholder, Adam B, Lavender, Christopher A, Fargo, David C, Adelman, Karen

    Published in Genes & development (01-01-2018)
    “…Regulation by gene-distal enhancers is critical for cell type-specific and condition-specific patterns of gene expression. Thus, to understand the basis of…”
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    Journal Article
  2. 2

    Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks by Williams, Lucy H., Fromm, George, Gokey, Nolan G., Henriques, Telmo, Muse, Ginger W., Burkholder, Adam, Fargo, David C., Hu, Guang, Adelman, Karen

    Published in Molecular cell (16-04-2015)
    “…The remarkable capacity for pluripotency and self-renewal in embryonic stem cells (ESCs) requires a finely tuned transcriptional circuitry wherein the pathways…”
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    Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass by Williams, Lucy H, Kalantry, Sundeep, Starmer, Joshua, Magnuson, Terry

    Published in Development (Cambridge) (15-05-2011)
    “…Repression of Xist RNA expression is considered a prerequisite to reversal of X-chromosome inactivation (XCI) in the mouse inner cell mass (ICM), and…”
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  5. 5

    Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation by Zeng, Gefei, Taylor, Sarah M., McColm, Janet R., Kappas, Nicholas C., Kearney, Joseph B., Williams, Lucy H., Hartnett, Mary E., Bautch, Victoria L.

    Published in Blood (15-02-2007)
    “…New blood vessel formation requires the coordination of endothelial cell division and the morphogenetic movements of vessel expansion, but it is not known how…”
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    Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility by Gu, Bin, Shorter, John R., Williams, Lucy H., Bell, Timothy A., Hock, Pablo, Dalton, Katherine A., Pan, Yiyun, Miller, Darla R., Shaw, Ginger D., Philpot, Benjamin D., Pardo‐Manuel de Villena, Fernando

    Published in Epilepsia (Copenhagen) (01-09-2020)
    “…Objective Animal studies remain essential for understanding mechanisms of epilepsy and identifying new therapeutic targets. However, existing animal models of…”
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