Search Results - "Williams, Lucy H."
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Widespread transcriptional pausing and elongation control at enhancers
Published in Genes & development (01-01-2018)“…Regulation by gene-distal enhancers is critical for cell type-specific and condition-specific patterns of gene expression. Thus, to understand the basis of…”
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Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks
Published in Molecular cell (16-04-2015)“…The remarkable capacity for pluripotency and self-renewal in embryonic stem cells (ESCs) requires a finely tuned transcriptional circuitry wherein the pathways…”
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Genomes of the Mouse Collaborative Cross
Published in Genetics (Austin) (01-06-2017)“…The Collaborative Cross (CC) is a multiparent panel of recombinant inbred (RI) mouse strains derived from eight founder laboratory strains. RI panels are…”
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Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass
Published in Development (Cambridge) (15-05-2011)“…Repression of Xist RNA expression is considered a prerequisite to reversal of X-chromosome inactivation (XCI) in the mouse inner cell mass (ICM), and…”
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Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation
Published in Blood (15-02-2007)“…New blood vessel formation requires the coordination of endothelial cell division and the morphogenetic movements of vessel expansion, but it is not known how…”
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Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility
Published in Epilepsia (Copenhagen) (01-09-2020)“…Objective Animal studies remain essential for understanding mechanisms of epilepsy and identifying new therapeutic targets. However, existing animal models of…”
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Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation. Commentary
Published in Blood (2007)Get full text
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