Search Results - "Williams, John P."
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Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting
Published in European journal of pharmacology (05-01-2014)“…Clinical research shows that postoperative nausea and vomiting (PONV) is caused primarily by the use of inhalational anesthesia and opioid analgesics. PONV is…”
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Molecular networks of human muscle adaptation to exercise and age
Published in PLoS genetics (01-03-2013)“…Physical activity and molecular ageing presumably interact to precipitate musculoskeletal decline in humans with age. Herein, we have delineated molecular…”
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Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women
Published in Clinical nutrition (Edinburgh, Scotland) (01-12-2018)“…Impaired anabolic responses to nutrition and exercise contribute to loss of skeletal muscle mass with ageing (sarcopenia). Here, we tested responses of muscle…”
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Teacher Professional Development on Self-Determination Theory-Based Design Thinking in STEM Education
Published in Educational Technology & Society (01-10-2021)“…Design thinking has become increasingly important in the context of the current movement toward integrated STEM education. Allied teaching practices often take…”
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Development of an instrument for exploring preservice technology teachers' maker-based technological pedagogical content knowledge
Published in British journal of educational technology (01-03-2021)“…With the development of the maker movement, more and more teachers are applying a broad range of technological tools in their pedagogy, instead of only…”
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Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients
Published in The American journal of clinical nutrition (01-11-2012)“…Background: Cachexia is a consequence of tumor burden caused by ill-defined catabolic alterations in muscle protein turnover.Objective: We aimed to explore the…”
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Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men
Published in Clinical science (1979) (01-11-2017)“…Leucine modulates muscle protein synthesis (MPS), with potential to facilitate accrual/maintenance of muscle mass. Animal models suggest that leucine boluses…”
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An initial development and validation of a Chinese technology teachers’ attitudes towards technology (TTATT) scale
Published in International journal of technology and design education (01-11-2020)“…Pupils’ attitudes towards technology have been widely discussed for over three decades, but the equally important topic of teachers’ attitudes towards…”
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Effects of infusing the engineering design process into STEM project-based learning to develop preservice technology teachers’ engineering design thinking
Published in International journal of STEM education (08-01-2021)“…Background This study focuses on probing preservice technology teachers’ cognitive structures and how they construct engineering design in technology-learning…”
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10
Glucagon‐like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle
Published in Aging cell (01-09-2020)“…Background Despite its known insulin‐independent effects, glucagon‐like peptide‐1 (GLP‐1) role in muscle protein turnover has not been explored under fed‐state…”
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The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply
Published in American journal of physiology: endocrinology and metabolism (01-09-2015)“…Essential amino acids (EAA) are responsible for skeletal muscle anabolic effects after nutrient intake. The pattern of appearance of EAA in blood, e.g., after…”
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Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (14-03-2018)“…The ability to rapidly generate and transfer muscle force is essential for effective corrective movements in order to prevent a fall. The aim of this study was…”
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Ovarian Damages Produced by Aerosolized Fine Particulate Matter (PM 2.5 ) Pollution in Mice: Possible Protective Medications and Mechanisms
Published in Chinese medical journal (20-06-2017)“…Ambient aerosol fine particulate matter (PM2.5) is associated with male reproductive toxicity in experiments and may have adverse effects in the female…”
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Creating Inclusive Schools for Autistic Students: A Scoping Review on Elements Contributing to Strengths-Based Approaches
Published in Education sciences (01-07-2023)“…Strengths-based approaches leveraging the strengths and interests of autistic students are increasingly recognised as important to meeting their school-related…”
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Physiological adaptations to resistance exercise as a function of age
Published in JCI insight (07-09-2017)“…The impact of resistance exercise training (RE-T) across the life span is poorly defined. To resolve this, we recruited three distinct age cohorts of young…”
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The effects of resistance exercise training on macro‐ and micro‐circulatory responses to feeding and skeletal muscle protein anabolism in older men
Published in The Journal of physiology (15-06-2015)“…Key points Increases in limb blood flow in response to nutrition are reduced in older age. Muscle microvascular blood flow (MBF) in response to nutrition is…”
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Associations between Plasma Branched Chain Amino Acids and Health Biomarkers in Response to Resistance Exercise Training Across Age
Published in Nutrients (02-10-2020)“…Leucine, isoleucine and valine (i.e., the branched chain amino acids, BCAA) play a key role in the support and regulation of tissue protein regulation and also…”
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A retrospective matched cohort study evaluating the effects of percutaneous endoscopic gastrostomy feeding tubes on nutritional status and survival in patients with advanced gastroesophageal malignancies undergoing systemic anti-cancer therapy
Published in PloS one (29-11-2017)“…Many patients with cancer or other systemic illnesses can experience malnutrition. One way to mitigate malnutrition is by insertion of a percutaneous…”
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The physiological impact of high‐intensity interval training in octogenarians with comorbidities
Published in Journal of cachexia, sarcopenia and muscle (01-08-2021)“…Background Declines in cardiorespiratory fitness (CRF) and fat‐free mass (FFM) with age are linked to mortality, morbidity and poor quality of life…”
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Dexmedetomidine prevents spatial learning and memory impairment induced by chronic REM sleep deprivation in rats
Published in Sleep and biological rhythms (01-07-2023)“…The study was attempted to investigate the effect on and mechanisms of action of dexmedetomidine with regard to learning and memory impairment in rats with…”
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