Search Results - "Williams, Jennifer A E"

Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina by Williams, Jennifer A E, Stampoulis, Dimitris, Gunter, Chloe E, Greenwood, John, Adamson, Peter, Moss, Stephen E

“…The purpose of this study was to examine the retinas of mice carrying hemizygous and null double deletions of Cfb-/- and Cfh-/-, and to compare these with the…”
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Retinal changes precede visual dysfunction in the complement factor H knockout mouse by Williams, Jennifer A E, Greenwood, John, Moss, Stephen E

“…We previously reported that aged mice lacking complement factor H (CFH) exhibit visual defects and structural changes in the retina. However, it is not known…”
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Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial by Marian, Ioana R, Goff, Megan, Williams, Jennifer A E, Gulati, Malvika, Chester-Jones, Mae, Francis, Anne, Watson, Marion, Vincent, Tonia L, Woollacott, Sue, Mackworth-Young, Charles, Glover, Victoria, Furniss, Dominic, Gardiner, Matthew, Lamb, Sarah E, Vincent, Katy, Barber, Vicki S, Black, Joanna, Dutton, Susan J, Watt, Fiona E

“…Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the…”
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The C-type Lectin Receptors CLEC-2 and Dectin-1, but Not DC-SIGN, Signal via a Novel YXXL-dependent Signaling Cascade by Fuller, Gemma L.J., Williams, Jennifer A.E., Tomlinson, Michael G., Eble, Johannes A., Hanna, Sheri L., Pöhlmann, Stefan, Suzuki-Inoue, Katsue, Ozaki, Yukio, Watson, Steve P., Pearce, Andrew C.

“…The two lectin receptors, CLEC-2 and Dectin-1, have been shown to signal through a Syk-dependent pathway, despite the presence of only a single YXXL in their…”
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Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis by Shi, Hui, Williams, Jennifer A. E., Guo, Li, Stampoulis, Dimitrios, Francesca Cordeiro, M., Moss, Stephen E.

“…The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are…”
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