Search Results - "Williams, Harriet"
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Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study
Published in Frontiers in aging neuroscience (23-07-2021)“…The ability to investigate therapeutic interventions in animal models of neurodegenerative diseases depends on extensive characterization of the model(s) being…”
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Motor Skill Performance and Physical Activity in Preschool Children
Published in Obesity (Silver Spring, Md.) (01-06-2008)“…Children with better‐developed motor skills may find it easier to be active and engage in more physical activity (PA) than those with less‐developed motor…”
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PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease‐protective variant PLCγ2 R522
Published in The EMBO journal (01-09-2021)“…Variants identified in genome‐wide association studies have implicated immune pathways in the development of Alzheimer’s disease (AD). Here, we investigated…”
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A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease
Published in Molecular neurodegeneration (10-11-2020)“…Late-onset Alzheimer's disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer's have focused on rare familial…”
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Adiposity and Neurological Disorders: A Review
Published in European Medical Journal. Neurology (25-04-2022)“…The rapid increase in the global incidence of obesity presents an ever-expanding set of medical, social, and economic challenges. Obesity is a complex disease,…”
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Motor competence and characteristics within the preschool environment
Published in Journal of science and medicine in sport (01-08-2017)“…Abstract Objectives Environmental characteristics within preschools that influence children’s motor competence are largely unknown. The purpose of the present…”
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Health-related quality of life in people with predementia Alzheimer's disease, mild cognitive impairment or dementia measured with preference-based instruments: a systematic literature review
Published in Alzheimer's research & therapy (18-11-2020)“…Obtaining reliable estimates of the health-related quality of life (HR-QoL) of people with predementia Alzheimer's disease [AD] (preclinical or prodromal AD),…”
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Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2R47H
Published in Frontiers in aging neuroscience (11-10-2021)“…Late-onset Alzheimer's disease (AD; LOAD) is the most common human neurodegenerative disease, however, the availability and efficacy of disease-modifying…”
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Non-contact infrared thermometers compared with current approaches in primary care for children aged 5 years and under: a method comparison study
Published in Health technology assessment (Winchester, England) (01-10-2020)“…Current options for temperature measurement in children presenting to primary care include either electronic axillary or infrared tympanic thermometers…”
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The Feldenkrais Method® can enhance cognitive function in independent living older adults: A case-series
Published in Journal of bodywork and movement therapies (01-07-2016)“…Summary Poor cognitive health a major concern of aging individuals, can compromise independent living. More than 16 million people in the United States are…”
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'The Listening Series': increasing equity, diversity and inclusion in patient and public involvement and engagement for policy research by listening to and learning from under-represented groups
Published in Research involvement and engagement (04-07-2024)“…Policy research aims to provide evidence to inform government policy decisions about health and social care. Engaging and involving the public and patients in…”
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Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)“…Introduction Hyperexcitability and epileptiform activity are commonplace in Alzheimer's disease (AD) patients and associated with impaired cognitive function…”
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Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2R47H
Published in Frontiers in aging neuroscience (07-02-2022)Get full text
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The relationships among gait and mobility under single and dual task conditions in community-dwelling older adults
Published in Aging clinical and experimental research (01-10-2011)“…Aims: The purpose of this study was to examine relationships among gait and mobility under single and dual task conditions in older adults. Methods:…”
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Effect of Feldenkrais exercises on dual task postural control in older adults
Published in Clinical interventions in aging (01-01-2014)“…Gerhild Ullmann,1 Harriet G Williams2 1Social and Behavioral Sciences, University of Memphis, School of Public Health, Memphis, TN, USA; 2Exercise Science,…”
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Young children's motor skill performance: Relationships with activity types and parent perception of athletic competence
Published in Journal of science and medicine in sport (01-11-2014)“…Abstract Objectives The aims were to examine the relationship between children's motor skill levels and types of physical activities performed during preschool…”
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Dissemination of an evidence-based program to reduce fear of falling, South Carolina, 2006-2009
Published in Preventing chronic disease (01-05-2012)“…Falls among older adults are a serious public health issue, and fear of falling can limit mobility, which in turn increases fall risk. A Matter of…”
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Prophylactic evaluation of verubecestat on disease‐ and symptom‐modifying effects in 5XFAD mice
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)“…Introduction Alzheimer's disease (AD) is the most common form of dementia. Beta‐secretase (BACE) inhibitors have been proposed as potential therapeutic…”
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A Field-Based Testing Protocol for Assessing Gross Motor Skills in Preschool Children: The Children's Activity and Movement in Preschool Study Motor Skills Protocol
Published in Measurement in physical education and exercise science (01-09-2009)“…The purpose of this study was to develop a valid and reliable tool for use in assessing motor skills in preschool children in field-based settings. The…”
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Carbohydrates and Physical/Mental Performance during Intermittent Exercise to Fatigue
Published in Medicine and science in sports and exercise (01-04-2002)“…Investigated the effects of carbohydrate-electrolyte (CHO) ingestion on physical and mental function associated with performing high-intensity exercise…”
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