Search Results - "Williams, Geraint P"

Corneal transplantation in the aftermath of the COVID-19 pandemic: an international perspective by Ang, Marcus, Moriyama, Aline, Colby, Kathryn, Sutton, Gerard, Liang, Lingyi, Sharma, Namrata, Hjortdal, Jesper, Shun Chiu Lam, Dennis, P Williams, Geraint, Armitage, John, S Mehta, Jodhbir

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Hyperopic refractive correction by LASIK, SMILE or lenticule reimplantation in a non-human primate model by Williams, Geraint P, Wu, Benjamin, Liu, Yu Chi, Teo, Ericia, Nyein, Chan L, Peh, Gary, Tan, Donald T, Mehta, Jodhbir S

“…Hyperopia is a common refractive error, apparent in 25% of Europeans. Treatments include spectacles, contact lenses, laser interventions and surgery including…”
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Cortisol biosynthesis in the human ocular surface innate immune response by Susarla, Radhika, Liu, Lei, Walker, Elizabeth A, Bujalska, Iwona J, Alsalem, Jawaher, Williams, Geraint P, Sreekantam, Sreekanth, Taylor, Angela E, Tallouzi, Mohammad, Southworth, H Susan, Murray, Philip I, Wallace, Graham R, Rauz, Saaeha

“…Innate immune responses have a critical role in regulating sight-threatening ocular surface (OcS) inflammation. While glucocorticoids (GCs) are frequently used…”
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Defining the Limits of Normal Conjunctival Fornix Anatomy in a Healthy South Asian Population by Khan, Imran J., FRCOphth, Ghauri, Abdul-Jabbar, MB, BCh, Hodson, James, BSc (Hons), Edmunds, Matthew R., MRCP, MRCOphth, Cottrell, Paul, BScOptom, Evans, Simon, BSc, Williams, Geraint P., PhD, FRCOphth, Rauz, Saaeha, PhD, FRCOphth

“…Purpose Quantifying the extent of conjunctival fibrosis for documentation of progression in conjunctival scarring disease is a clinical challenge. Measurement…”
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Defining Ocular Surface Disease Activity and Damage Indices by an International Delphi Consultation by Mathewson, Priscilla A., MA(cantab), FRCOphth, Williams, Geraint P., PhD, FRCOphth, Watson, Stephanie L., PhD, FRANZCO, Hodson, James, BSc(Hons), Bron, Anthony J., FRCOphth, FMedSci, Rauz, Saaeha, PhD, FRCOphth (MISS)

“…Abstract Purpose Unifying terminology for the description of ocular surface disease (OSD) is vital for determining treatment responses and ensuring robust…”
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Initial experiences of cataract & lens surgery in 1269 patients in outpatient clean rooms using a portable laminar air flow device by Patel, Radhika Pooja, While, Benjamin, Smith, Alaric, Deutsch, John, Scotcher, Stephen, Morphis, Georgios, Williams, Geraint P., Madge, Simon N.

“…Background In 2020, routine cataract surgery was halted in most countries due to the COVID-19 pandemic in order to reduce transmission. With a consequent lack…”
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Biomechanical evaluation of porcine lens capsule with and without nucleus after capsulotomy - Finite element analysis by Wong, Yoke-Rung, Williams, Geraint P, George, Benjamin L, Yam, Gary Hin-Fai, Ang, Marcus Han-Nian, Mehta, Jodhbir S, Tay, Shian-Chao

“…Previous studies have shown that the nucleus could offer structural support to the lens capsule. This study investigated the biomechanical performance of…”
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Nerve regeneration by human corneal stromal keratocytes and stromal fibroblasts by Yam, Gary Hin-Fai, Williams, Geraint P., Setiawan, Melina, Yusoff, Nur Zahirah Binte M., Lee, Xiao-wen, Htoon, Hla Myint, Zhou, Lei, Fuest, Matthias, Mehta, Jodhbir S.

“…Laser refractive surgeries reshape corneal stroma to correct refractive errors, but unavoidably affect corneal nerves. Slow nerve regeneration and atypical…”
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Neuron J is a rapid and reliable open source tool for evaluating corneal nerve density in herpes simplex keratitis by Cottrell, Paul, Ahmed, Sohail, James, Catherine, Hodson, James, McDonnell, Peter J, Rauz, Saaeha, Williams, Geraint P

“…In vivo confocal microscopy (IVCM) demonstrates reduction in corneal sub-basal nerve density in herpes simplex keratitis (HSK). Image J is an open source…”
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Conjunctival Neutrophils Predict Progressive Scarring in Ocular Mucous Membrane Pemphigoid by Williams, Geraint P, Nightingale, Peter, Southworth, Sue, Denniston, Alastair K O, Tomlins, Paul J, Turner, Stephen, Hamburger, John, Bowman, Simon J, Curnow, S John, Rauz, Saaeha

“…Ocular mucous membrane pemphigoid (OcMMP) is a rare autoimmune disorder resulting in progressive conjunctival fibrosis and ocular surface failure leading to…”
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Periodontitis prevalence and serum antibody reactivity to periodontal bacteria in primary Sjögren's syndrome: a pilot study by Lugonja, Bozo, Yeo, Lorraine, Milward, Michael R., Smith, Diana, Dietrich, Thomas, Chapple, Iain L. C., Rauz, Saaeha, Williams, Geraint P., Barone, Francesca, de Pablo, Paola, Buckley, Chris, Hamburger, John, Richards, Andrea, Poveda-Gallego, Ana, Scheel-Toellner, Dagmar, Bowman, Simon J.

“…Aims The aims of this study were as follows: (i) To assess the prevalence of periodontitis among patients with primary Sjögren's syndrome (pSS) and comparator…”
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Performing Reliable Lens Capsulotomy in the Presence of Corneal Edema With a Femtosecond Laser by Williams, Geraint P, George, Benjamin L, Wong, Yoke R, Yam, Gary H F, Ang, Marcus, Tay, Shian C, Mehta, Jodhbir S

“…To determine the effects of the Ziemer LDV Z8 liquid interface femtosecond laser platform during capsulotomy under different energy settings in the presence of…”
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Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery by Ong, Hon Shing, Farook, Mohamed, Tan, Benjamin Boon Chuan, Williams, Geraint P, Santhiago, Marcony R, Mehta, Jodhbir S

“…A percentage tissue altered (PTA) score of ≥40% has been advocated as an independent indicator of post-operative ectasia risk following laser in-situ…”
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The effects of a low-energy, high frequency liquid optic interface femtosecond laser system on lens capsulotomy by Williams, Geraint P., George, Ben L., Wong, Yoke R., Seah, Xin-Yi, Ang, Heng-Pei, Loke, Mun Kitt A., Tay, Shian Chao, Mehta, Jod S.

“…The introduction of femtosecond laser assisted cataract surgery (FLACS) is a paradigm changing approach in cataract surgery, the most commonly performed…”
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Higher-Order-Aberrations Following Hyperopia Treatment: Small Incision Lenticule Extraction, Laser-Assisted In Situ Keratomileusis and Lenticule Implantation by Liu, Yu-Chi, Wen, Jiaxin, Teo, Ericia Pei Wen, Williams, Geraint P, Lwin, Nyein Chan, Mehta, Jodhbir S

“…To compare the postoperative higher-order-aberrations (HOAs) after hyperopic small incision lenticule extraction (SMILE), hyperopic laser-assisted in situ…”
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Corneal lenticule storage before reimplantation by Liu, Yu-Chi, Williams, Geraint P, George, Ben L, Soh, Yu Qiang, Seah, Xin Yi, Peh, Gary Swee Lim, Yam, Gary Hin Fai, Mehta, Jodhbir S

“…To explore the optimal lenticule storage conditions that maintain lenticule integrity and clarity. A total of 99 lenticules obtained from myopic patients…”
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Cytokine production and antigen recognition by human mucosal homing conjunctival effector memory CD8+ T cells by Williams, Geraint P, Pachnio, Annette, Long, Heather M, Rauz, Saaeha, Curnow, S John

“…Conjunctival epithelial T cells are dominated by CD3(+)CD56-TCRαβ(+)CD8αβ(+) lymphocytes. In this study we explored the antigen experience status, mucosal…”
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Endogenous cortisol and TGF-beta in human aqueous humor contribute to ocular immune privilege by regulating dendritic cell function by Denniston, Alastair K, Kottoor, Sherine H, Khan, Imran, Oswal, Kadambari, Williams, Geraint P, Abbott, Joseph, Wallace, Graham R, Salmon, Mike, Rauz, Saaeha, Murray, Philip I, Curnow, S John

“…Aqueous humor (AqH) has been shown to have significant immunosuppressive effects on APCs in animal models. We wanted to establish whether, in humans, AqH can…”
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Patient priorities in herpes simplex keratitis by Liu, Xiaoxuan, Kolli, Sai, McDonnell, Peter, Patel, Amit, Quinlan, Michael, Skym, Kevin, Denniston, Alastair K, Shah, Peter, Williams, Geraint P

“…ObjectiveHerpes simplex keratitis (HSK) is a sight-threatening disease and a leading cause of infectious corneal blindness. Involving patients in setting the…”
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Aqueous humor suppression of dendritic cell function helps maintain immune regulation in the eye during human uveitis by Denniston, Alastair K, Tomlins, Paul, Williams, Geraint P, Kottoor, Sherine, Khan, Imran, Oswal, Kadambari, Salmon, Mike, Wallace, Graham R, Rauz, Saaeha, Murray, Philip I, Curnow, S John

“…Noninfectious uveitis is characterized by a dysregulated inflammatory or immune response in the eye. It is unclear whether this represents a failure of immune…”
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