Search Results - "Williams, Gareth J."
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Coral reef ecosystem services in the Anthropocene
Published in Functional ecology (01-06-2019)“…Coral reefs underpin a range of ecosystem goods and services that contribute to the well‐being of millions of people. However, tropical coral reefs in the…”
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High frequency temperature variability reduces the risk of coral bleaching
Published in Nature communications (26-04-2018)“…Coral bleaching is the detrimental expulsion of algal symbionts from their cnidarian hosts, and predominantly occurs when corals are exposed to thermal stress…”
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Acid/Base-Triggered Switching of Circularly Polarized Luminescence and Electronic Circular Dichroism in Organic and Organometallic Helicenes
Published in Chemistry : a European journal (19-01-2015)“…Electronic circular dichroism and circularly polarized luminescence acid/base switching activity has been demonstrated in helicene‐bipyridine proligand 1 a and…”
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4
Near-island biological hotspots in barren ocean basins
Published in Nature communications (16-02-2016)“…Phytoplankton production drives marine ecosystem trophic-structure and global fisheries yields. Phytoplankton biomass is particularly influential near coral…”
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Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair
Published in Progress in biophysics and molecular biology (01-03-2015)“…The Mre11-Rad50-Nbs1 (MRN) complex is a dynamic macromolecular machine that acts in the first steps of DNA double strand break repair, and each of its…”
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Phosphorescence vs Fluorescence in Cyclometalated Platinum(II) and Iridium(III) Complexes of (Oligo)thienylpyridines
Published in Inorganic chemistry (18-04-2011)“…Two newly prepared oligothienylpyridines, 5-(2-pyridyl)-5′-dodecyl-2,2′-bithiophene, HL2 , and 5-(2-pyridyl)-5′′-dodecyl-2,2′:5′,2′′-ter-thiophene, HL3 , bind…”
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ATM-Deficient Cancers Provide New Opportunities for Precision Oncology
Published in Cancers (14-03-2020)“…Poly-ADP ribose polymerase (PARP) inhibitors are currently used in the treatment of several cancers carrying mutations in the breast and ovarian cancer…”
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ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining
Published in Nucleic acids research (21-07-2023)“…Abstract Ataxia-telangiectasia mutated (ATM) drives the DNA damage response via modulation of multiple signal transduction and DNA repair pathways. Previously,…”
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Co‐occurrence of herbivorous fish functional groups correlates with enhanced coral reef benthic state
Published in Global ecology and biogeography (01-03-2023)“…Aim Biodiversity loss is impacting essential ecosystem functions and services across the globe. Recently, our interest in the benefits of biodiversity for…”
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Insights into FlaI Functions in Archaeal Motor Assembly and Motility from Structures, Conformations, and Genetics
Published in Molecular cell (28-03-2013)“…Superfamily ATPases in type IV pili, type 2 secretion, and archaella (formerly archaeal flagella) employ similar sequences for distinct biological processes…”
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Reef Fish Survey Techniques: Assessing the Potential for Standardizing Methodologies
Published in PloS one (25-04-2016)“…Dramatic changes in populations of fishes living on coral reefs have been documented globally and, in response, the research community has initiated efforts to…”
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Pathogenesis of a Tissue Loss Disease Affecting Multiple Species of Corals Along the Florida Reef Tract
Published in Frontiers in Marine Science (01-11-2019)“…An outbreak of stony coral tissue loss disease (SCTLD), emerged on reefs off the coast of southeast Florida in 2014 and continues to spread throughout…”
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Local human impacts decouple natural biophysical relationships on Pacific coral reefs
Published in Ecography (Copenhagen) (01-08-2015)“…Human impacts can homogenize and simplify ecosystems, favoring communities that are no longer naturally coupled with (or reflective of) the background…”
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Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
Published in DNA repair (10-12-2010)“…Repair and integrity of DNA ends at breaks, replication forks and telomeres are essential for life; yet, paradoxically, these responses are, in many cases,…”
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Local genomic adaptation of coral reef-associated microbiomes to gradients of natural variability and anthropogenic stressors
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-2014)“…Holobionts are species-specific associations between macro- and microorganisms. On coral reefs, the benthic coverage of coral and algal holobionts varies due…”
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A robust operational model for predicting where tropical cyclone waves damage coral reefs
Published in Scientific reports (17-05-2016)“…Tropical cyclone (TC) waves can severely damage coral reefs. Models that predict where to find such damage (the ‘damage zone’) enable reef managers to: 1)…”
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enantio-Enriched CPL-active helicene-bipyridine-rhenium complexes
Published in Chemical communications (Cambridge, England) (04-03-2015)“…The incorporation of a rhenium atom within an extended helical π-conjugated bi-pyridine system impacts the chiroptical and photophysical properties of the…”
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Metallahelicenes: Easily Accessible Helicene Derivatives with Large and Tunable Chiroptical Properties
Published in Angewandte Chemie (01-01-2010)“…Enantiopure metallahelicenes have been prepared by cyclometalation of 2‐pyridyl‐substituted benzophenanthrenes followed by resolution using chiral HPLC. They…”
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Regional reef fish assemblage maps provide baseline biogeography for tropicalization monitoring
Published in Scientific reports (03-04-2024)“…The Anthropocene rise in global temperatures is facilitating the expansion of tropical species into historically non-native subtropical locales, including…”
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RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles
Published in Nature communications (24-07-2023)“…RAD51C is an enigmatic predisposition gene for breast, ovarian, and prostate cancer. Currently, missing structural and related functional understanding limits…”
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