Search Results - "Williams, E. David"

Statistics of antibody binding to the spike protein explain the dependence of COVID 19 infection risk on antibody concentration and affinity by Williams, David E.

“…The increase of COVID-19 breakthrough infection risk with time since vaccination has a clear relationship to the decrease of antibody concentration with time…”
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Indoles Derived From Glucobrassicin: Cancer Chemoprevention by Indole-3-Carbinol and 3,3'-Diindolylmethane by Williams, David E

“…Hydrolysis of glucobrassicin by plant or bacterial myrosinase produces multiple indoles predominantly indole-3-carbinol (I3C). I3C and its major product,…”
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Point of Care Diagnostics: Status and Future by Gubala, Vladimir, Harris, Leanne F, Ricco, Antonio J, Tan, Ming X, Williams, David E

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Local supersaturation and the growth of protective scales during CO2 corrosion of steel: Effect of pH and solution flow by Sk, Mobbassar Hassan, Abdullah, Aboubakr M., Ko, Monika, Ingham, Bridget, Laycock, Nick, Arul, Rakesh, Williams, David. E.

“…•Kinetics of formation of protective siderite scale during CO2 corrosion elucidated.•Observed current is sum of crystallisation and dissolution as carbonato…”
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Direct Writing and Characterization of Three-Dimensional Conducting Polymer PEDOT Arrays by Zhang, Peikai, Aydemir, Nihan, Alkaisi, Maan, Williams, David E, Travas-Sejdic, Jadranka

“…Direct writing is an effective and versatile technique for three-dimensional (3D) fabrication of conducting polymer (CP) structures. It is precisely localized…”
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Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles by Tivnan, Amanda, Orr, Wayne Shannon, Gubala, Vladimir, Nooney, Robert, Williams, David E, McDonagh, Colette, Prenter, Suzanne, Harvey, Harry, Domingo-Fernández, Raquel, Bray, Isabella M, Piskareva, Olga, Ng, Catherine Y, Lode, Holger N, Davidoff, Andrew M, Stallings, Raymond L

“…Neuroblastoma is one of the most challenging malignancies of childhood, being associated with the highest death rate in paediatric oncology, underlining the…”
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Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane by Kishimoto, Takuma, Mioka, Tetsuo, Itoh, Eriko, Williams, David E, Andersen, Raymond J, Tanaka, Kazuma

“…Sterols are important lipid components of the plasma membrane (PM) in eukaryotic cells, but it is unknown how the PM retains sterols at a high concentration…”
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Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism by Krueger, Sharon K, Williams, David E

“…Flavin-containing monooxygenase (FMO) oxygenates drugs and xenobiotics containing a "soft-nucleophile", usually nitrogen or sulfur. FMO, like cytochrome P450…”
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Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor by Andersen, Raymond J., Mawji, Nasrin R., Wang, Jun, Wang, Gang, Haile, Simon, Myung, Jae-Kyung, Watt, Kate, Tam, Teresa, Yang, Yu Chi, Bañuelos, Carmen A., Williams, David E., McEwan, Iain J., Wang, Yuzhou, Sadar, Marianne D.

“…Castration-recurrent prostate cancer (CRPC) is suspected to depend on androgen receptor (AR). The AF-1 region in the amino-terminal domain (NTD) of AR contains…”
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The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif by Williams, Leslie K, Zhang, Xiaohua, Caner, Sami, Tysoe, Christina, Nguyen, Nham T, Wicki, Jacqueline, Williams, David E, Coleman, John, McNeill, John H, Yuen, Violet, Andersen, Raymond J, Withers, Stephen G, Brayer, Gary D

“…Montbretin A is a potent inhibitor of amylase, an enzyme critical in starch digestion and thus of relevance for diabetes and obesity. Structural and…”
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Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors by Kim, Eunah, Bisson, William H, Löhr, Christiane V, Williams, David E, Ho, Emily, Dashwood, Roderick H, Rajendran, Praveen

“…Acetylation is an important, reversible post-translational modification affecting histone and non-histone proteins with critical roles in gene transcription,…”
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Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer by Bedard, Mary C., Chihanga, Tafadzwa, Carlile, Adrean, Jackson, Robert, Brusadelli, Marion G., Lee, Denis, VonHandorf, Andrew, Rochman, Mark, Dexheimer, Phillip J., Chalmers, Jeffrey, Nuovo, Gerard, Lehn, Maria, Williams, David E. J., Kulkarni, Aditi, Carey, Molly, Jackson, Amanda, Billingsley, Caroline, Tang, Alice, Zender, Chad, Patil, Yash, Wise-Draper, Trisha M., Herzog, Thomas J., Ferris, Robert L., Kendler, Ady, Aronow, Bruce J., Kofron, Matthew, Rothenberg, Marc E., Weirauch, Matthew T., Van Doorslaer, Koenraad, Wikenheiser-Brokamp, Kathryn A., Lambert, Paul F., Adam, Mike, Steven Potter, S., Wells, Susanne I.

“…Persistent HPV16 infection is a major cause of the global cancer burden. The viral life cycle is dependent on the differentiation program of stratified…”
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Total synthesis and isolation of citrinalin and cyclopiamine congeners by Mercado-Marin, Eduardo V., Garcia-Reynaga, Pablo, Romminger, Stelamar, Pimenta, Eli. F., Romney, David K., Lodewyk, Michael W., Williams, David E., Andersen, Raymond J., Miller, Scott J., Tantillo, Dean J., Berlinck, Roberto G. S., Sarpong, Richmond

“…Many natural products that contain basic nitrogen atoms—for example alkaloids like morphine and quinine—have the potential to treat a broad range of human…”
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A Novel Assay for Antibody-Dependent Cell-Mediated Cytotoxicity against HIV-1- or SIV-Infected Cells Reveals Incomplete Overlap with Antibodies Measured by Neutralization and Binding Assays by ALPERT, Michael D, HEYER, Lisa N, WILLIAMS, David E. J, HARVEY, Jackson D, GREENOUGH, Thomas, ALLHORN, Maria, EVANS, David T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework by Teeguarden, Justin G, Tan, Yu-Mei, Edwards, Stephen W, Leonard, Jeremy A, Anderson, Kim A, Corley, Richard A, Kile, Molly L, Simonich, Staci M, Stone, David, Tanguay, Robert L, Waters, Katrina M, Harper, Stacey L, Williams, David E

“…Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health,…”
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Reversible Electrochemical Switching of Polymer Brushes Grafted onto Conducting Polymer Films by Pei, Yiwen, Travas-Sejdic, Jadranka, Williams, David E

“…We demonstrate the electrochemical switching of conformation of surface-bound polymer brushes, by grafting environmentally sensitive polymer brushes from an…”
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Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [14C]-BaP by Vermillion Maier, Monica L., Siddens, Lisbeth K., Pennington, Jamie M., Uesugi, Sandra L., Anderson, Kim A., Tidwell, Lane G., Tilton, Susan C., Ognibene, Ted J., Turteltaub, Kenneth W., Smith, Jordan N., Williams, David E.

“…[Display omitted] •Human dose–response study of carcinogen BaP at environmental levels with UPLC-AMS.•UPLC-AMS of [14C]-BaP and metabolites over 4 doses in…”
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Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice by Clarke, John D., Hsu, Anna, Williams, David E., Dashwood, Roderick H., Stevens, Jan F., Yamamoto, Masayuki, Ho, Emily

“…ABSTRACT Purpose To determine the metabolism and tissue distribution of the dietary chemoprotective agent sulforaphane following oral administration to…”
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Sesterterpenoids Isolated from the Sponge Phorbas sp. Activate Latent HIV‑1 Provirus Expression by Wang, Meng, Tietjen, Ian, Chen, Min, Williams, David E, Daoust, Julie, Brockman, Mark A, Andersen, Raymond J

“…Eight new sesterterpenoids, alotaketals D (8) and E (9), ansellones D (10), E (11), F (12), and G (13), and anvilones A (14) and B (15), have been isolated…”
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Isolation, synthesis and bioactivity studies of phomactin terpenoids by Kuroda, Yusuke, Nicacio, Karen J., da Silva-Jr, Ildefonso Alves, Leger, Paul R., Chang, Stanley, Gubiani, Juliana R., Deflon, Victor M., Nagashima, Nozomu, Rode, Alexander, Blackford, Katherine, Ferreira, Antonio G., Sette, Lara D., Williams, David E., Andersen, Raymond J., Jancar, Sonia, Berlinck, Roberto G. S., Sarpong, Richmond

“…Studies of secondary metabolites (natural products) that cover their isolation, chemical synthesis and bioactivity investigation present myriad opportunities…”
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