Search Results - "Williams, Darren Reece"

Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion by Cho, Haaglim, Seo, Youngha, Loke, Kin Man, Kim, Seon-Wook, Oh, Seong-Min, Kim, Jun-Hyeong, Soh, Jihee, Kim, Hyoen Sik, Lee, Hyunju, Kim, Jin, Min, Jung-Joon, Jung, Da-Woon, Williams, Darren Reece

“…Abstract Purpose: M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into…”
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Integrated drug response prediction models pinpoint repurposed drugs with effectiveness against rhabdomyosarcoma by Baek, Bin, Jang, Eunmi, Park, Sejin, Park, Sung-Hye, Williams, Darren Reece, Jung, Da-Woon, Lee, Hyunju

“…Targeted therapies for inhibiting the growth of cancer cells or inducing apoptosis are urgently needed for effective rhabdomyosarcoma (RMS) treatment. However,…”
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SR proteins regulate V 6 exon splicing of CD44 pre-mRNA by Loh, Tiing Jen, Moon, Heegyum, Jang, Ha Na, Liu, Yongchao, Choi, Namjeong, Shen, Shengfu, Williams, Darren Reece, Jung, Da-Woon, Zheng, Xuexiu, Shen, Haihong

“…CD44 pre-mRNA includes 20 exons, of which exons 1-5 ($C_1-C_5$) and exons 16-20 ($C_6-C_{10}$) are constant exons, whereas exons 6-15 ($V_1-V_{10}$) are…”
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Reprogram or Reboot: Small Molecule Approaches for the Production of Induced Pluripotent Stem Cells and Direct Cell Reprogramming by Jung, Da-Woon, Kim, Woong-Hee, Williams, Darren Reece

“…Stem cell transplantation is a potential therapy for regenerative medicine, which aims to restore tissues damaged by trauma, aging, and diseases. Since its…”
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Age Is Just a Number: Progress and Obstacles in the Discovery of New Candidate Drugs for Sarcopenia by Kim, Hyun-Jun, Jung, Da-Woon, Williams, Darren Reece

“…Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and function that occurs with aging. The progression of sarcopenia is…”
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Making cardiomyocytes with your chemistry set:Small molecule-induced cardiogenesis in somatic cells by Kim, Woong-Hee, Jung, Da-Woon, Williams, Darren Reece

“…Cell transplantation is an attractive potential therapy for heart diseases. For example, myocardial infarction(MI) is a leading cause of mortality in many…”
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Chemical Targeting of GAPDH Moonlighting Function in Cancer Cells Reveals Its Role in Tubulin Regulation by Jung, Da-Woon, Kim, Woong-Hee, Seo, Shinae, Oh, Eunsang, Yim, Soon-Ho, Ha, Hyung-Ho, Chang, Young-Tae, Williams, Darren Reece

“…Glycolytic enzymes are attractive anticancer targets. They also carry out numerous, nonglycolytic “moonlighting” functions in cells. In this study, we…”
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Integrated drug response prediction models pinpoint repurposed drugs with effectiveness against rhabdomyosarcoma by Bin Baek, Eunmi Jang, Sejin Park, Sung-Hye Park, Darren Reece Williams, Da-Woon Jung, Hyunju Lee

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Cancer-stimulated CAFs enhance monocyte differentiation and pro-tumoral TAM activation via IL-6 and GM-CSF secretion by Cho, Haaglim, Seo, Youngha, Loke, Kin Man, Kim, Seon-Wook, Oh, Seong-Min, Kim, Jun-Hyeong, Soh, Jihee, Kim, Hyeon-Sik, Lee, Hyunju, Kim, Jin, Min, Jung-Joon, Jung, Da-Woon, Williams, Darren Reece

“…M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into M2 TAMs via a…”
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SR proteins regulate V 6 exon splicing of CD44 pre-mRNA by Loh, Tiing Jen, Moon, Heegyum, Jang, Ha Na, Liu, Yongchao, Choi, Namjeong, Shen, Shengfu, Williams, Darren Reece, Jung, Da-Woon, Zheng, Xuexiu, Shen, Haihong

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hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron by Loh, Tiing Jen, Cho, Sunghee, Moon, Heegyum, Jang, Ha Na, Williams, Darren Reece, Jung, Da-Woon, Kim, Il-Chul, Ghigna, Claudia, Biamonti, Giuseppe, Zheng, Xuexiu, Shen, Haihong

“…CD44 is a complex cell adhesion molecule that mediates communication and adhesion between adjacent cells as well as between cells and the extracellular matrix…”
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SR proteins regulate V6 exon splicing of CD44 pre-mRNA by Loh, Tiing Jen, Moon, Heegyum, Jang, Ha Na, Liu, Yongchao, Choi, Namjeong, Shen, Shengfu, Williams, Darren Reece, Jung, Da-Woon, Zheng, Xuexiu, Shen, Haihong

“…CD44 pre-mRNA includes 20 exons, of which exons 1-5 (C -C ) and exons 16-20 (C -C ) are constant exons, whereas exons 6-15 (V -V ) are variant exons. V…”
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Lessons from the swamp: developing small molecules that confer salamander muscle cellularization in mammals by Um, JungIn, Jung, Da-Woon, Williams, Darren Reece

“…The ability of salamanders, such as newts, to regenerate damaged tissues has been studied for centuries. A prominent example of this regenerative power is the…”
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