Search Results - "Williams, Charles C"

Small cell lung cancer by Kalemkerian, Gregory P, Akerley, Wallace, Bogner, Paul, Borghaei, Hossein, Chow, Laura Qm, Downey, Robert J, Gandhi, Leena, Ganti, Apar Kishor P, Govindan, Ramaswamy, Grecula, John C, Hayman, James, Heist, Rebecca Suk, Horn, Leora, Jahan, Thierry, Koczywas, Marianna, Loo, Jr, Billy W, Merritt, Robert E, Moran, Cesar A, Niell, Harvey B, O'Malley, Janis, Patel, Jyoti D, Ready, Neal, Rudin, Charles M, Williams, Jr, Charles C, Gregory, Kristina, Hughes, Miranda

“…Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in…”
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Clinical outcomes of patients with advanced gastrointestinal stromal tumors: Safety and efficacy in a worldwide treatment‐use trial of sunitinib by Reichardt, Peter, Kang, Yoon‐Koo, Rutkowski, Piotr, Schuette, Jochen, Rosen, Lee S., Seddon, Beatrice, Yalcin, Suayib, Gelderblom, Hans, Williams, Charles C., Fumagalli, Elena, Biasco, Guido, Hurwitz, Herbert I., Kaiser, Pamela E., Fly, Kolette, Matczak, Ewa, Chen, Liang, Lechuga, Maria José, Demetri, George D.

“…BACKGROUND The objectives of this study were to provide sunitinib to patients with gastrointestinal stromal tumor (GIST) who were otherwise unable to obtain it…”
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Effects of self-directed stress management training and home-based exercise on quality of life in cancer patients receiving chemotherapy: a randomized controlled trial by Jacobsen, Paul B., Phillips, Kristin M., Jim, Heather S. L., Small, Brent J., Faul, Leigh Anne, Meade, Cathy D., Thompson, Lora, Williams Jr, Charles C., Loftus, Loretta S., Fishman, Mayer, Wilson, Rick W.

“…Background Research has shown that self‐directed stress management training improves mental well‐being in patients undergoing chemotherapy. The present study…”
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LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells by Marqués-Torrejón, María Ángeles, Williams, Charles A. C., Southgate, Benjamin, Alfazema, Neza, Clements, Melanie P., Garcia-Diaz, Claudia, Blin, Carla, Arranz-Emparan, Nerea, Fraser, Jane, Gammoh, Noor, Parrinello, Simona, Pollard, Steven M.

“…Adult neural stem cells (NSCs) must tightly regulate quiescence and proliferation. Single-cell analysis has suggested a continuum of cell states as NSCs exit…”
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Neurophysiology of Drosophila Models of Parkinson's Disease by Elliott, Christopher J. H., Williams, Charles A. C., Furmston, Rebecca, West, Ryan J. H.

“…We provide an insight into the role Drosophila has played in elucidating neurophysiological perturbations associated with Parkinson’s disease- (PD-) related…”
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Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer by Chiappori, Alberto A., Williams, Charles C., Gray, Jhanelle E., Tanvetyanon, Tawee, Haura, Eric B., Creelan, Ben C., Thapa, Ram, Chen, Dung-Tsa, Simon, George R., Bepler, Gerold, Gabrilovich, Dmitry I., Antonia, Scott J.

“…Small cell lung cancer TP53 mutations lead to expression of tumor antigens that elicits specific cytotoxic T-cell immune responses. In this phase II study,…”
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Effects of Jaw Clenching and Jaw Alignment Mouthpiece Use on Force Production During Vertical Jump and Isometric Clean Pull by Allen, Charles R, Fu, Yang-Chieh, Cazas-Moreno, Vanessa, Valliant, Melinda W, Gdovin, Jacob R, Williams, Charles C, Garner, John C

“…ABSTRACTAllen, CR, Fu, Y-C, Cazas-Moreno, V, Valliant, MW, Gdovin, JR, Williams, CC, and Garner, JC. Effects of jaw clenching and jaw alignment mouthpiece use…”
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A Phase I, Pharmacokinetic, and Pharmacodynamic Study of Panobinostat, an HDAC Inhibitor, Combined with Erlotinib in Patients with Advanced Aerodigestive Tract Tumors by GRAY, Jhanelle E, HAURA, Eric, TETTEH, Leticia, AKAR, Angela, XIUHUA ZHAO, SCHELL, Michael J, BEPLER, Gerold, ALTIOK, Soner, CHIAPPORI, Alberto, TANVETYANON, Tawee, WILLIAMS, Charles C, PINDER-SCHENCK, Mary, KISH, Julie A, KREAHLING, Jenny, LUSH, Richard, NEUGER, Anthony

“…Panobinostat, a histone deacetylase (HDAC) inhibitor, enhances antiproliferative activity in non-small cell lung cancer (NSCLC) cell lines when combined with…”
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Impact of shoe and cleat type on youth baseball pitching biomechanics by Gdovin, Jacob R., Wade, Chip, Williams, Charles C., Luginsland, Lauren A., Wilson, Samuel J., Garner, John C.

“…Shoulder and elbow injuries among baseball pitchers of various ages and abilities continue to rise despite exhaustive efforts analysing pitch type and count;…”
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The Effects of Various Weighted Implements on Baseball Swing Kinematics in Collegiate Baseball Players by Williams, Charles C, Gdovin, Jacob R, Wilson, Samuel J, Cazas-Moreno, Vanessa L, Eason, John D, Hoke, Elizabeth L, Allen, Charles R, Wade, Chip, Garner, John C

“…ABSTRACTWilliams, CC, Gdovin, JR, Wilson, SJ, Cazas-Moreno, VL, Eason, JD, Hoke, EL, Allen, CR, Wade, C, and Garner, JC. The effects of various weighted…”
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Small cell lung cancer clinical practice guidelines in oncology by Johnson, Bruce E, Crawford, Jeffrey, Downey, Robert J, Ettinger, David S, Fossella, Frank, Grecula, John C, Jahan, Thierry, Kalemkerian, Gregory P, Kessinger, Anne, Koczywas, Marianna, Langer, Corey J, Martins, Renato, Marymont, Maryanne Hoffman, Niell, Harvey B, Ramnath, Nithya, Robert, Francisco, Williams, Jr, Charles C

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Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors by Creelan, Ben C, Gabrilovich, Dmitry I, Gray, Jhanelle E, Williams, Charles C, Tanvetyanon, Tawee, Haura, Eric B, Weber, Jeffrey S, Gibney, Geoffrey T, Markowitz, Joseph, Proksch, Joel W, Reisman, Scott A, McKee, Mark D, Chin, Melanie P, Meyer, Colin J, Antonia, Scott J

“…Omaveloxolone is a semisynthetic oleanane triterpenoid that potently activates Nrf2 with subsequent antioxidant function. We conducted a first-in-human Phase I…”
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Post-translational modification of SOX family proteins: Key biochemical targets in cancer? by Williams, Charles A.C., Soufi, Abdenour, Pollard, Steven M.

“…Sox proteins are a family of lineage-associated transcription factors. They regulate expression of genes involved in control of self-renewal and multipotency…”
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Phase I Study of a Novel Taxane BMS-188797 in Adult Patients with Solid Malignancies by GARRETT, Christopher R, FISHMAN, Mayer N, SULLIVAN, Daniel M, RAGO, Randall R, WILLIAMS, Charles C, DELLAPORTAS, Anne M, MAHANY, J. Joseph, LUSH, Richard M, DALTON, William S, GOLLERKERI, Ashwin, COHEN, Marvin B

“…Purpose: Preclinical studies show that BMS-188797 has a broad spectrum of antitumor activity in in vitro cytotoxicity assays and tumor xenograft models. We did…”
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The Influence of an Acute Bout of Whole Body Vibration on Human Postural Control Responses by Wilson, Samuel J., Williams, Charles C., Gdovin, Jacob R., Eason, John D., Luginsland, Lauren A., Hill, Christopher M., Chander, Harish, Wade, Chip, Garner, John C.

“…The use of vibrating platforms has become increasingly available, and popular at sports and rehabilitation institutes. Given the discrepancies in the…”
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Patient, caregiver and physician perspectives on participating in a thoracic rapid tissue donation program by Quinn, Gwendolyn P., Pentz, Rebecca D., Muñoz-Antonia, Teresita, Boyle, Theresa A., Schabath, Matthew B., Pratt, Christie L., Shaffer, Andrea, Duarte, Luisa F., Bowman-Curci, Meghan, Antonia, Scott J., Chiappori, Alberto A., Creelan, Benjamin C., Gray, Jhanelle E., Williams, Charles C., Haura, Eric B.

“…•Rapid Tissue Donation (RTD) recruitment poses several ethical challenges.•Exploring patient and family perspectives is critical for successful…”
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Comparison of Countermovement and Squat Jumps Performance In Recreationally Trained Males by Donahue, Paul T, Wilson, Samuel J, Williams, Charles C, Hill, Christopher M, Garner, John C

“…The vertical jump has been shown to be an effective tool in assessing neuromuscular fatigue. The two most common iterations of the vertical jump are the…”
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Phase II trial of a GM-CSF-producing and CD40L-expressing bystander cell line combined with an allogeneic tumor cell-based vaccine for refractory lung adenocarcinoma by Creelan, Ben C, Antonia, Scott, Noyes, David, Hunter, Terri B, Simon, George R, Bepler, Gerold, Williams, Charles C, Tanvetyanon, Tawee, Haura, Eric B, Schell, Michael J, Chiappori, Alberto

“…We created a vaccine in which irradiated allogeneic lung adenocarcinoma cells are combined with a bystander K562 cell line transfected with hCD40L and hGM-CSF…”
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A phase 2 cooperative group adjuvant trial using a biomarker‐based decision algorithm in patients with stage I non‐small cell lung cancer (SWOG‐0720, NCT00792701) by Bepler, Gerold, Zinner, Ralph G., Moon, James, Calhoun, Royce, Kernstine, Kemp, Williams, Charles C., Mack, Philip C., Oliveira, Vasco, Zheng, Zhong, Stella, Philip J., Redman, Mary W., Gandara, David R.

“…BACKGROUND This cooperative group adjuvant phase 2 trial in patients with completely resected stage I non‐small cell lung cancer with tumor diameters measuring…”
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Increased Bioavailability of Intravenous Versus Oral CI-1033, a Pan erbB Tyrosine Kinase Inhibitor: Results of a Phase I Pharmacokinetic Study by Simon, George R, Garrett, Christopher R, Olson, Stephen C, Langevin, Michael, Eiseman, Irene A, Mahany, John J, Williams, Charles C, Lush, Richard, Daud, Adil, Munster, Pamela, Chiappori, Alberto, Fishman, Mayer, Bepler, Gerold, Lenehan, Peter F, Sullivan, Daniel M

“…Purpose: In phase I studies with oral CI-1033, dose-limiting toxicities were primarily gastrointestinal, supporting the exploration of i.v. dosing to achieve…”
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