Search Results - "Williams, Cecilia"

Development and implementation of assays to monitor human adenovirus F40/41 in wastewater: Trends preceding, during, and following the non-A-to-E hepatitis outbreak in Stockholm by Perez-Zabaleta, Mariel, Williams, Cecilia, Cetecioglu, Zeynep

“…[Display omitted] •The hexon-based assay can be used for monitoring HAdV-F41 from lineage 2.•We present a fiber-based assay that detects a wider coverage of…”
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Sink or Swim? A survival analysis of sport dropout in Australian youth swimmers by Moulds, Kylie, Abbott, Shaun, Pion, Johan, Brophy‐Williams, Cecilia, Heathcote, Mark, Cobley, Stephen

“…Objectives To examine long‐term participation and dropout rates in Australian youth swimming using survival analyses and to determine whether multiple…”
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Colitis‐induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity by Ibrahim, Ahmed, Hugerth, Luisa W., Hases, Linnea, Saxena, Ashish, Seifert, Maike, Thomas, Quentin, Gustafsson, Jan‐Åke, Engstrand, Lars, Williams, Cecilia

“…Chronic inflammation of the colon (colitis) is a risk factor for colorectal cancer (CRC). Hormone‐replacement therapy reduces CRC incidences, and the estrogen…”
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Insufficient antibody validation challenges oestrogen receptor beta research by Andersson, Sandra, Sundberg, Mårten, Pristovsek, Nusa, Ibrahim, Ahmed, Jonsson, Philip, Katona, Borbala, Clausson, Carl-Magnus, Zieba, Agata, Ramström, Margareta, Söderberg, Ola, Williams, Cecilia, Asplund, Anna

“…The discovery of oestrogen receptor β (ERβ/ ESR2 ) was a landmark discovery. Its reported expression and homology with breast cancer pharmacological target ERα…”
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Editorial: Role of Sex Steroids and Their Receptor in Cancers by Giovannelli, Pia, Ramaraj, Pandurangan, Williams, Cecilia

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Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant by Simon, Marisa, Mesmar, Fahmi, Helguero, Luisa, Williams, Cecilia

“…Triple-negative breast cancer (TNBC) is an aggressive, highly recurrent breast cancer subtype, affecting approximately one-fifth of all breast cancer patients…”
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Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice by Hases, Linnea, Birgersson, Madeleine, Indukuri, Rajitha, Archer, Amena, Williams, Cecilia

“…There are significant sex differences in colorectal cancer (CRC), including in incidence, onset, and molecular characteristics. Further, while inflammatory…”
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Estrogen Receptors β1 and β2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3 by Dey, Prasenjit, Jonsson, Philip, Hartman, Johan, Williams, Cecilia, Ström, Anders, Gustafsson, Jan-Åke

“…The estrogen receptor (ER)β1 is successively lost during cancer progression, whereas its splice variant, ERβ2, is expressed in advanced prostate cancer. The…”
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The Importance of Sex in the Discovery of Colorectal Cancer Prognostic Biomarkers by Hases, Linnea, Ibrahim, Ahmed, Chen, Xinsong, Liu, Yanghong, Hartman, Johan, Williams, Cecilia

“…Colorectal cancer (CRC) is the third leading cause of cancer deaths. Advances within bioinformatics, such as machine learning, can improve biomarker discovery…”
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Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1 by Birgersson, Madeleine, Indukuri, Rajitha, Lindquist, Linnéa, Stepanauskaite, Lina, Luo, Qing, Deng, Qiaolin, Archer, Amena, Williams, Cecilia

“…Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of action is mainly uncharacterized. We here…”
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Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis by Sommerauer, Christian, Gallardo-Dodd, Carlos J, Savva, Christina, Hases, Linnea, Birgersson, Madeleine, Indukuri, Rajitha, Shen, Joanne X, Carravilla, Pablo, Geng, Keyi, Nørskov Søndergaard, Jonas, Ferrer-Aumatell, Clàudia, Mercier, Grégoire, Sezgin, Erdinc, Korach-André, Marion, Petersson, Carl, Hagström, Hannes, Lauschke, Volker M, Archer, Amena, Williams, Cecilia, Kutter, Claudia

“…Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen…”
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Sexual dimorphism in the incidence of human cancers by Zheng, Daoshan, Trynda, Justyna, Williams, Cecilia, Vold, Jeremy A, Nguyen, Justin H, Harnois, Denise M, Bagaria, Sanjay P, McLaughlin, Sarah A, Li, Zhaoyu

“…Sex differences in the incidences of cancers become a critical issue in both cancer research and the development of precision medicine. However, details in…”
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miR-206 inhibits cell migration through direct targeting of the actin-binding protein Coronin 1C in triple-negative breast cancer by Wang, Jun, Tsouko, Efrosini, Jonsson, Philip, Bergh, Jonas, Hartman, Johan, Aydogdu, Eylem, Williams, Cecilia

“…Patients with triple-negative breast cancer (TNBC) have an overall poor prognosis, which is primarily due to a high metastatic capacity of these tumors. Novel…”
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Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells by Indukuri, Rajitha, Hases, Linnea, Archer, Amena, Williams, Cecilia

“…Inflammation is a primary component of both initiation and promotion of colorectal cancer (CRC). Cytokines secreted by macrophages, including tumor necrosis…”
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ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions by Song, Dandan, He, Huan, Indukuri, Rajitha, Huang, Zhiqiang, Stepanauskaite, Lina, Sinha, Indranil, Haldosén, Lars-Arne, Zhao, Chunyan, Williams, Cecilia

“…The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and function as ligand-inducible transcription factors. They are…”
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High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice by Hases, Linnea, Stepanauskaite, Lina, Birgersson, Madeleine, Brusselaers, Nele, Schuppe-Koistinen, Ina, Archer, Amena, Engstrand, Lars, Williams, Cecilia

“…A high-fat diet can lead to gut microbiota dysbiosis, chronic intestinal inflammation, and metabolic syndrome. Notably, resulting phenotypes, such as glucose…”
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The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells by Monteiro, Fátima Liliana, Vitorino, Rui, Wang, Jun, Cardoso, Hugo, Laranjeira, Hugo, Simões, Joana, Caldas, Margarida, Henrique, Rui, Amado, Francisco, Williams, Cecilia, Jerónimo, Carmen, Helguero, Luisa A

“…Abstract Proliferation and differentiation are controlled through chromatin remodelling. Therefore, there is an enormous biological significance and clinical…”
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Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival by Dória, M. Luisa, Ribeiro, Ana S., Wang, Jun, Cotrim, Cândida Z., Domingues, Pedro, Williams, Cecilia, Domingues, M. Rosário, Helguero, Luisa A.

“…This work combined gene and protein expression, gas chromatography‐flame ionization detector, and hydrophilic interaction liquid chromatography‐tandem mass…”
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Comparison of serum exosome isolation methods on co-precipitated free microRNAs by Cheng, Yirui, Qu, Xiangyun, Dong, Zhaonan, Zeng, Qingyu, Ma, Xueqing, Jia, Yunli, Li, Ruochen, Jiang, Xiaoxu, Williams, Cecilia, Wang, Tao, Xia, Weiliang

“…Exosomes are nano-sized extracellular vesicles containing different biomolecules such as proteins and microRNAs (miRNAs) that mediate intercellular…”
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Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer by Dey, Prasenjit, Velazquez-Villegas, Laura A, Faria, Michelle, Turner, Anthony, Jonsson, Philp, Webb, Paul, Williams, Cecilia, Gustafsson, Jan-Åke, Ström, Anders M

“…The estrogen receptor (ER) β variant ERβ2 is expressed in aggressive castration-resistant prostate cancer and has been shown to correlate with decreased…”
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