Search Results - "Williams, C Andrew"

Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer's disease brains by Rose, Shannon E, Williams, C Andrew, Hailey, Dale W, Mishra, Swati, Kirkland, Amanda, Keene, C Dirk, Garden, Gwenn A, Jayadev, Suman, Young, Jessica E

“…Abnormal endo-lysosomal morphology is an early cytopathological feature of Alzheimer's disease (AD) and genome-wide association studies (GWAS) have implicated…”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM by Bashore, Frances M, Katis, Vittorio L, Du, Yuhong, Sikdar, Arunima, Wang, Dongxue, Bradshaw, William J, Rygiel, Karolina A, Leisner, Tina M, Chalk, Rod, Mishra, Swati, Williams, C Andrew, Gileadi, Opher, Brennan, Paul E, Wiley, Jesse C, Gockley, Jake, Cary, Gregory A, Carter, Gregory W, Young, Jessica E, Pearce, Kenneth H, Fu, Haian, Axtman, Alison D

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative…”
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Pharmacologic enhancement of retromer rescues endosomal pathology induced by defects in the Alzheimer’s gene SORL1 by Mishra, Swati, Knupp, Allison, Kinoshita, Chizuru, Williams, C. Andrew, Rose, Shannon E., Martinez, Refugio, Theofilas, Panos, Young, Jessica E.

“…The SORL1 gene (SORLA) is strongly associated with risk of developing Alzheimer’s disease (AD). SORLA is a regulator of endosomal trafficking in neurons and…”
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The role of glucose in supporting motility and capacitation in human spermatozoa by Williams, A. C, Ford, W. C

“…Glucose has been reported to be beneficial to human sperm for optimal capacitation and fertilization, although it is unclear whether glucose is required for…”
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The war on error by Evers, Johannes L.H., Sharpe, Richard M., Somigliana, Edgardo, Williams, Andrew C.

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Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors by Zwart, Ruud, Carbone, Anna L, Moroni, Mirko, Bermudez, Isabel, Mogg, Adrian J, Folly, Elizabeth A, Broad, Lisa M, Williams, Andrew C, Zhang, Deyi, Ding, Chunjin, Heinz, Beverly A, Sher, Emanuele

“…Sazetidine-A has been recently proposed to be a "silent desensitizer" of alpha4beta2 nicotinic acetylcholine receptors (nAChRs), implying that it desensitizes…”
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An alternative strategy to the Pictet–Spengler method for tetrahydroisoquinoline synthesis: a feasibility study by Henderson, Laura, Knight, David W., Williams, Andrew C.

“…Acid-catalysed cyclisations of the 2-aminoethyl styrene derivatives 9 give good to excellent yields of the corresponding tetrahydroisoquinolines 7 by an…”
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Optimised conditions for styrene syntheses using Suzuki–Miyaura couplings and catalyst-ligand-base pre-mixes by Henderson, Laura, Knight, David W., Rutkowski, Piotr, Williams, Andrew C.

“…Optimised conditions are reported for Suzuki–Miyaura couplings between N-tosyl-2-bromo-benzylamines and -phenethylamines with vinylboronic acids, using…”
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Selenocyclisations of homoallylic sulfonamides: stereoselective methods for the elaboration of substituted pyrrolidines, pyrrolines and derivatives by Jones, Andrew D., Redfern, Adele L., Knight, David W., Morgan, Ian R., Williams, Andrew C.

“…Selenocyclisations of the homoallylic sulfonamides [e.g., 26, 28 and 30] using phenylselanyl halides lead exclusively to β-selanyl-pyrrolidines [e.g., 27, 29…”
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Acylnitrilium ion-initiated heteroannulations in alkaloid synthesis. An efficient, stereocontrolled, total synthesis of the Orchidaceae alkaloid (.+-.)-dendrobine by Lee, Cheol Hae, Westling, Mark, Livinghouse, Tom, Williams, Andrew C

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An individual-based simulation of pneumonic plague transmission following an outbreak and the significance of intervention compliance by Williams, Andrew D.C, Hall, Ian M, Rubin, G. James, Amlôt, Richard, Leach, Steve

“…Abstract The existence of primary pneumonic plague outbreaks raises concerns over the use of the causative bacteria as an aerosol-based bioweapon. We employed…”
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Altmetrics, huh? by Evers, J.L.H. (Hans), Williams, Andrew C.

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative…”
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Parental Perceptions of Participation in the Special Education Process by Williams, Andrew C

“…This study examines parental perceptions of their participation in the special education process at a high school in southern Illinois. Eleven parents were…”
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Synthetic applications of Group V metallacyclopropenes. Part 1. Group V metallacyclopropenes in synthesis. An efficient route to polyfunctional ring systems via the cocyclization of diynes with substituted monoacetylenes by Williams, Andrew C, Sheffels, Pamela, Sheehan, Derek, Livinghouse, Tom

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First organophosphorus radical-mediated cyclisations to afford medium-sized rings: eight-membered lactones and seven- and eight-membered lactams by Lang, Stuart, Corr, Michael, Muir, Neil, Khan, Tanweer A., Schönebeck, Franziska, Murphy, John A., Payne, Andrew H., Williams, Andrew C.

“…[Display omitted] The phosphorus based radical precursors N-ethylpiperidine hypophosphite (EPHP) and diethylphosphine oxide (DEPO) are efficient reagents for…”
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A versatile protocol for the preparation of substituted 1- and 2-naphthyl piperazines from aminonaphthols by Bueno, Ana B., Flynn, Claire J., Gilmore, Jeremy, Marcos, Alicia, Montero, Carlos, Porter, Warren, Williams, Andrew C.

“…Aminonaphthols are easily transformed into a variety of 1- and 2-naphthyl piperazines using a sequence of diazotization reaction, iodide substitution and Pd(0)…”
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