Search Results - "Williams, Berea A. R."

Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds by Williams, Berea A. R, Diehnelt, Chris W, Belcher, Paul, Greving, Matthew, Woodbury, Neal W, Johnston, Stephen A, Chaput, John C

“…A full understanding of the proteome will require ligands to all of the proteins encoded by genomes. While antibodies represent the principle affinity reagents…”
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Evolution of a Histone H4-K16 Acetyl-Specific DNA Aptamer by Williams, Berea A. R, Lin, Liyun, Lindsay, Stuart M, Chaput, John C

“…We report the in vitro selection of DNA aptamers that bind to histone H4 proteins acetylated at lysine 16. The best aptamer identified in this selection binds…”
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Self-Assembled Peptide Nanoarrays: An Approach to Studying Protein-Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

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Recognition Imaging of Acetylated Chromatin Using a DNA Aptamer by Lin, Liyun, Fu, Qiang, Williams, Berea A.R., Azzaz, Abdelhamid M., Shogren-Knaak, Michael A., Chaput, John C., Lindsay, Stuart

“…Histone acetylation plays an important role in the regulation of gene expression. A DNA aptamer generated by in vitro selection to be highly specific for…”
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Creating protein biocatalysts as tools for future industrial applications by Chaput, John C, Woodbury, Neal W, Stearns, Linda A, Williams, Berea A R

“…Biocatalysts provide an economical and energy-efficient alternative to traditional chemical manufacturing processes. For processes where biocatalysts currently…”
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The evolvability of lead peptides from small library screens by Zhang, Jinglei, Williams, Berea A R, Nilsson, Mikael T, Chaput, John C

“…Very little is known about the evolvability of lead peptides that are isolated from small library screens. Here we begin to explore this question by comparing…”
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Random mutagenesis by error-prone PCR by McCullum, Elizabeth O, Williams, Berea A R, Zhang, Jinglei, Chaput, John C

“…In vitro selection coupled with directed evolution represents a powerful method for generating nucleic acids and proteins with desired functional properties…”
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Self-Assembled Peptide Nanoarrays: An Approach to Studying Protein-Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

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Synthesis of peptide-oligonucleotide conjugates using a heterobifunctional crosslinker by Williams, Berea A R, Chaput, John C

“…Peptide-oligonucleotide conjugates (POCs) are molecular chimeras composed of a nucleic acid moiety covalently attached to a polypeptide moiety. POCs have been…”
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Self‐Assembled Peptide Nanoarrays: An Approach to Studying Protein–Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

“…On show: High‐density peptide arrays capable of displaying many different amino acid sequences at well‐defined and addressable locations on the same DNA…”
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Self‐Assembled Peptide Nanoarrays: An Approach to Studying Protein–Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

“…Hochdichte Peptidanordnungen, die eine Vielzahl unterschiedlicher Aminosäuresequenzen an genau definierten und addressierbaren Stellen derselben…”
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Self‐Assembled Peptide Nanoarrays: An Approach to Studying Protein–Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

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