Search Results - "Williams, Beatrice A."

An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells by Buckler, Keith J., Williams, Beatrice A., Honore, Eric

“…The biophysical and pharmacological properties of an oxygen-sensitive background K + current in rat carotid body type-I cells were investigated and compared…”
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Calcium sparks activate calcium-dependent Cl- current in rat corpus cavernosum smooth muscle cells by Williams, Beatrice A, Sims, Stephen M

“…Spontaneous transient currents, due to activation of Ca(2+)-dependent K(+) and Cl(-) channels, occur in corpus cavernosum smooth muscle cells (CCSMC) of the…”
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Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells by Williams, Beatrice A, Buckler, Keith J

“…The single channel properties of TASK-like oxygen-sensitive potassium channels were studied in rat carotid body type 1 cells. We observed channels with rapid…”
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Estimating the Sensitivity of Mechanosensitive Ion Channels to Membrane Strain and Tension by Charras, Guillaume T., Williams, Beatrice A., Sims, Stephen M., Horton, Mike A.

“…Bone adapts to its environment by a process in which osteoblasts and osteocytes sense applied mechanical strain. One possible pathway for the detection of…”
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Z/I and A-band lattice spacings in frog skeletal muscle: effects of contraction and osmolarity by Irving, T C, Li, Q, Williams, B A, Millman, B M

“…A-band and Z-line/I-band lattice spacings were measured by small-angle X-ray diffraction from relaxed and isometrically-contracting whole frog sartorius…”
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Rate-Dependent Effects of Sematilide on Ventricular Monophasic Action Potential Duration and Delayed Rectifier K+ Current in Rabbits by Beatch, Gregory N, Davis, Darryl R, Laganière, Sylvie, Williams, Beatrice A

“…SUMMARYOur objective was to define the actions of sematilide in rabbits and to assess the contribution of the delayed rectifier (IK) to rate dependence of…”
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The role of TASK-like K+ channels in oxygen sensing in the carotid body by Buckler, Keith J, Williams, Beatrice A, Orozco, Rodrigo Varas, Wyatt, Christopher N

“…The carotid body plays an important role in initiating protective responses to hypoxemia. The primary oxygen sensing cells are the glomus or type 1 cells…”
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Kinetics of rate‐dependent shortening of action potential duration in guinea‐pig ventricle; effects of I K1 and I Kr blockade by Williams, Beatrice A, Dickenson, David R, Beatch, Gregory N

“…The kinetics of shortening of action potential duration (APD) following an increase in pacing rate, from 2 to 3.3 Hz, was characterized in guinea‐pig…”
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Regulation of intracellular Ca2+ release in corpus cavernosum smooth muscle: synergism between nitric oxide and cGMP by Williams, Beatrice A, Liu, Caiqiong, Deyoung, Ling, Brock, Gerald B, Sims, Stephen M

“…Tonic contraction of corpus cavernosum smooth muscle cells (SMCs) maintains the flaccid state of the penis, and relaxation is initiated by nitric oxide (NO),…”
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Magnesium shifts voltage dependence of activation of delayed rectifier I(K) in guinea pig ventricular myocytes by Williams, B A, Beatch, G N

“…The sensitivity of the delayed rectifier K+ current (I(K)) to intracellular Mg2+ was investigated in guinea pig ventricular myocytes using the whole cell…”
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Kinetics of rate‐dependent shortening of action potential duration in guinea‐pig ventricle; effects of IK1 and IKr blockade by Williams, Beatrice A, Dickenson, David R, Beatch, Gregory N

“…The kinetics of shortening of action potential duration (APD) following an increase in pacing rate, from 2 to 3.3 Hz, was characterized in guinea‐pig…”
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Block of ATP‐sensitive K+ channels in isolated mouse pancreatic β‐cells by 2,3‐butanedione monoxime by Smith, Paul A., Williams, Beatrice A., Ashcroft, Frances M.

“…1 The patch‐clamp technique has been used to examine the action of the chemical phosphatase 2,3‐butanedione monoxime (BDM) on ATP‐sensitive K+ channels…”
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Amantadine and sparteine inhibit ATP‐regulated K‐currents in the insulin‐secreting β‐cell line, HIT‐T15 by Ashcroft, Frances M., Kerr, Amanda J., Gibson, John S., Williams, Beatrice A.

“…1 The effects of pharmacological agents that potentiate insulin release were studied on ATP‐regulated K‐currents (K‐ATP currents) in the insulin‐secreting…”
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