Search Results - "Williams, BS"

Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes by Felix, John P, Williams, Brande S, Priest, Birgit T, Brochu, Richard M, Dick, Ivy E, Warren, Vivien A, Yan, Lizhen, Slaughter, Robert S, Kaczorowski, Gregory J, Smith, McHardy M, Garcia, Maria L

“…The discovery of novel therapeutic agents that act on voltage-gated sodium channels requires the establishment of high-capacity screening assays that can…”
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Synthesis and SAR of 1,2- trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockers by Ok, Dong, Li, Chunshi, Abbadie, Catherine, Felix, John P., Fisher, Michael H., Garcia, Maria L., Kaczorowski, Gregory J., Lyons, Kathryn A., Martin, William J., Priest, Birgit T., Smith, McHardy M., Williams, Brande S., Wyvratt, Matthew J., Parsons, William H.

“…Novel cyclopentane-based 3-phenyl-1-hydroxypropyl compounds were evaluated for inhibitory activity against the peripheral nerve and sodium channel Na V1.7 and…”
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Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain by Liang, Jun, Brochu, Richard M., Cohen, Charles J., Dick, Ivy E., Felix, John P., Fisher, Michael H., Garcia, Maria L., Kaczorowski, Gregory J., Lyons, Kathryn A., Meinke, Peter T., Priest, Birgit T., Schmalhofer, William A., Smith, McHardy M., Tarpley, Jason W., Williams, Brande S., Martin, William J., Parsons, William H.

“…The discovery and structure–activity relationship (SAR) studies of a novel class of sodium channel blockers are disclosed. A new series of voltage-gated sodium…”
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Operation of terahertz quantum-cascade lasers at 164 K in pulsed mode and at 117 K in continuous-wave mode by Williams, Benjamin, Kumar, Sushil, Hu, Qing, Reno, John

“…We report the demonstration of a terahertz quantum-cascade laser that operates up to 164 K in pulsed mode and 117 K in continuous-wave mode at approximately…”
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Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis by Tielbeek, Jorim J., Uffelmann, Emil, Williams, Benjamin S., Colodro-Conde, Lucía, Gagnon, Éloi, Mallard, Travis T., Levitt, Brandt E., Jansen, Philip R., Johansson, Ada, Sallis, Hannah M., Pistis, Giorgio, Saunders, Gretchen R. B., Allegrini, Andrea G., Rimfeld, Kaili, Konte, Bettina, Klein, Marieke, Hartmann, Annette M., Salvatore, Jessica E., Nolte, Ilja M., Demontis, Ditte, Malmberg, Anni L. K., Burt, S. Alexandra, Savage, Jeanne E., Sugden, Karen, Poulton, Richie, Harris, Kathleen Mullan, Vrieze, Scott, McGue, Matt, Iacono, William G., Mota, Nina Roth, Mill, Jonathan, Viana, Joana F., Mitchell, Brittany L., Morosoli, Jose J., Andlauer, Till F. M., Ouellet-Morin, Isabelle, Tremblay, Richard E., Côté, Sylvana M., Gouin, Jean-Philippe, Brendgen, Mara R., Dionne, Ginette, Vitaro, Frank, Lupton, Michelle K., Martin, Nicholas G., Castelao, Enrique, Räikkönen, Katri, Eriksson, Johan G., Lahti, Jari, Hartman, Catharina A., Oldehinkel, Albertine J., Snieder, Harold, Liu, Hexuan, Preisig, Martin, Whipp, Alyce, Vuoksimaa, Eero, Lu, Yi, Jern, Patrick, Rujescu, Dan, Giegling, Ina, Palviainen, Teemu, Kaprio, Jaakko, Harden, Kathryn Paige, Munafò, Marcus R., Morneau-Vaillancourt, Geneviève, Plomin, Robert, Viding, Essi, Boutwell, Brian B., Aliev, Fazil, Dick, Danielle M., Popma, Arne, Faraone, Stephen V., Børglum, Anders D., Medland, Sarah E., Franke, Barbara, Boivin, Michel, Pingault, Jean-Baptiste, Glennon, Jeffrey C., Barnes, J. C., Fisher, Simon E., Moffitt, Terrie E., Caspi, Avshalom, Polderman, Tinca J. C., Posthuma, Danielle

“…Despite the substantial heritability of antisocial behavior (ASB), specific genetic variants robustly associated with the trait have not been identified. The…”
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Immuno-PET Imaging of the Programmed Cell Death-1 Ligand (PD-L1) Using a Zirconium-89 Labeled Therapeutic Antibody, Avelumab by Jagoda, Elaine M., Vasalatiy, Olga, Basuli, Falguni, Opina, Ana Christina L., Williams, Mark R., Wong, Karen, Lane, Kelly C., Adler, Steve, Ton, Anita Thein, Szajek, Lawrence P., Xu, Biying, Butcher, Donna, Edmondson, Elijah F., Swenson, Rolf E., Greiner, John, Gulley, James, Eary, Janet, Choyke, Peter L.

“…Objective: The goal is to evaluate avelumab, an anti-PD-L1 monoclonal immunoglobulin G antibody labeled with zirconium-89 in human PD-L1-expressing cancer…”
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3.4-THz quantum cascade laser based on longitudinal-optical-phonon scattering for depopulation by Williams, Benjamin S., Callebaut, Hans, Kumar, Sushil, Hu, Qing, Reno, John L.

“…We report the development of a quantum cascade laser, at λ=87.2 μm, corresponding to 3.44 THz or 14.2 meV photon energy. The GaAs/Al0.15Ga0.85As laser…”
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1.9 THz Quantum-cascade Lasers with One-well Injector by Kumar, Sushil, Williams, Benjamin S., Hu, Qing, Reno, John L.

“…We report terahertz quantum-cascade lasers operating predominantly at 1.90 THz with side modes as low as 1.86 THz (lambda approx. equal to 161 micrometers,…”
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Arthroscopic Decompression of Calcific Tendinitis of the Shoulder and Repair of Residual Rotator Cuff Defect by Brusalis, Christopher M., Streepy, John T., Williams, Tyler, Garelick, Sydney, Garrigues, Grant E.

“…Background: Calcific tendinitis is a common source of shoulder pain and represents pathologic deposition of calcium hydroxyapatite within rotator cuff tendon…”
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Continuous-wave operation of terahertz quantum-cascade lasers above liquid-nitrogen temperature by Kumar, Sushil, Williams, Benjamin S., Kohen, Stephen, Hu, Qing, Reno, John L.

“…We report cw operation of a quantum-cascade laser at 3.2 THz (λ≈94 μm) up to a heat-sink temperature of 93 K. Resonant longitudinal-optical phonon scattering…”
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Giant isolated profunda femoris artery aneurysm treated with aneurysmal ligation without profunda femoris artery revascularization by Rahman, Naveed A., Williams, Zachary E., Choudhry, Asad, Surowiec, Scott

“…Isolated nonruptured profunda femoris artery (PFA) aneurysms are exceedingly rare. We present the case of an 80-year-old man who initially presented with a…”
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A Geographic Needs Assessment for Approved Cleft Care in the United States by Parham, Matthew, Williams, Austin, Layon, Sarah, Burns, Heather, Abu-Ghname, Amjed, Hollier, Larry

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Endovascular salvage of occluded renal artery after >15 hours of ischemic time by Williams, Zachary E., DeNoble, Daniel, Rahman, Naveed A., Choudhry, Asad, Feghali, Anthony

“…In severe cases of acute traumatic injury to the kidney, immediate intervention is necessary to avoid irreversible ischemic damage. This case involves a…”
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5. Comparing Liposomal Bupivacaine (Exparel®), Bupivacaine-soaked Gelfoam®, and ON-Q Ropivacaine for Alleviating Donor Site Pain Following Alveolar Bone Grafting by Layon, Sarah A., Williams, Austin D., Burns, Heather R., Parham, Matthew J., Monson, Laura A., Buchanan, Edward P.

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Axillary nerve decompression: case report and arthroscopic surgical technique by Harkin, William E., Scanaliato, John P., Kerzner, Benjamin, Williams, Tyler, Garelick, Sydney, Nicholson, Gregory P., Garrigues, Grant E.

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Antimicrobial activity of extracts from macroalgae Ulva lactuca against clinically important Staphylococci is impacted by lunar phase of macroalgae harvest by Deveau, A.M., Miller‐Hope, Z., Lloyd, E., Williams, B.S., Bolduc, C., Meader, J.M., Weiss, F., Burkholder, K.M.

“…Staphylococcus aureus is a common human bacterial pathogen that causes skin and soft tissue infections. Methicillin‐resistant Staph. aureus (MRSA) are…”
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Reactions of Vinyl Acetate and Vinyl Trifluoroacetate with Cationic Diimine Pd(II) and Ni(II) Alkyl Complexes:  Identification of Problems Connected with Copolymerizations of These Monomers with Ethylene by Williams, B. Scott, Leatherman, Mark D, White, Peter S, Brookhart, Maurice

“…Vinyl acetate (VA) and vinyl trifluoroacetate (VAf) react with [(N∧N)Pd(Me)(L)][X] (M = Pd, Ni, (N∧N) = N,N‘-1,2-acenaphthylenediylidene bis(2,6-dimethyl…”
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Evaluation of Adult Reconstruction and Arthroplasty Fellowships in the United States Based on Academic Productivity by Williams, Nicholas R., Guzman, Alvarho J., Dela Rueda, Therese, Francisco, Raia, Shin, Caleb, Haratian, Ryan, McGahan, Patrick J., Chen, James L.

“…Institutional academic productivity varies on an individual level. This study aims to analyze the research output of adult reconstruction and arthroplasty…”
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Terahertz heterodyne receiver based on a quantum cascade laser and a superconducting bolometer by Gao, J. R., Hovenier, J. N., Yang, Z. Q., Baselmans, J. J. A., Baryshev, A., Hajenius, M., Klapwijk, T. M., Adam, A. J. L., Klaassen, T. O., Williams, B. S., Kumar, S., Hu, Q., Reno, J. L.

“…We report the first demonstration of an all solid-state heterodyne receiver that can be used for high-resolution spectroscopy above 2 THz suitable for…”
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Geospatial Demand for Approved Cleft Care in the United States by Parham, Matthew J, Williams, Austin D, Layon, Sarah A, Burns, Heather R, Abu-Ghname, Amjed, Hollier, Larry H

“…Geographic information systems are powerful tools for characterizing the geospatial factors influencing access to care. As patients with cleft lip and/or…”
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