Search Results - "Williams, Alfred"

MEKK2 mediates aberrant ERK activation in neurofibromatosis type I by Bok, Seoyeon, Shin, Dong Yeon, Yallowitz, Alisha R., Eiseman, Mark, Cung, Michelle, Xu, Ren, Li, Na, Sun, Jun, Williams, Alfred L., Scott, John E., Su, Bing, Shim, Jae-Hyuck, Greenblatt, Matthew B.

“…Neurofibromatosis type I (NF1) is characterized by prominent skeletal manifestations caused by NF1 loss. While inhibitors of the ERK activating kinases MEK1/2…”
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Neuroprotective effects of an in vitro BBB permeable phenoxythiophene sulfonamide small molecule in glutamate‑induced oxidative injury by Pokharel, Smritee, Gliyazova, Nailya S, Dandepally, Srinivasa R, Williams, Alfred L, Ibeanu, Gordon C

“…Reactive oxygen species (ROS) play a central role in oxidative stress-associated neuronal cell death during ischemia. Further investigation into the inhibition…”
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Old Drug New Use―Amoxapine and Its Metabolites as Potent Bacterial β-Glucuronidase Inhibitors for Alleviating Cancer Drug Toxicity by REN KONG, LIU, Timothy, XIAOPING ZHU, AHMAD, Syed, WILLIAMS, Alfred L, PHAN, Alexandria T, HONG ZHAO, SCOTT, John E, YEH, Li-An, WONG, Stephen T. C

“…Irinotecan (CPT-11) induced diarrhea occurs frequently in patients with cancer and limits its usage. Bacteria β-glucuronidase (GUS) enzymes in intestines…”
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The RANKL/RANK/OPG Signaling Pathway Mediates Medial Arterial Calcification in Diabetic Charcot Neuroarthropathy by NDIP, Agbor, WILLIAMS, Alfred, JUDE, Edward B, SERRACINO-INGLOTT, Ferdinand, RICHARDSON, Steve, SMYTH, J. V, BOULTON, Andrew J. M, ALEXANDER, M. Yvonne

“…The receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) signaling pathway (RANKL/RANK/OPG signaling) is implicated…”
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Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2) by Ahmad, Syed, St. Hilaire, Valentine R., Dandepally, Srinivasa R., Johnson, Gary L., Williams, Alfred L., Scott, John E.

“…The kinase MEKK2 (MAP3K2) activates the MEK5/ERK5 cell signaling pathway and may play an important role in tumor growth and metastasis. Thus, MEKK2 may…”
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Liebeskind–Srogl cross coupling mediated synthesis of verbenachalcone by Dandepally, Srinivasa Reddy, Williams, Alfred L.

“…A flexible and scalable total synthesis of verbenachalcone is achieved in eight linear steps from commercially cheap available starting material,…”
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Regioselective Reduction of 3-Substituted N-Acylpyrazinium Salts toward the Synthesis of 1,2-Dihydropyrazines by Williams, Alfred L, St. Hilaire, Valentine R, Lee, Tina

“…The regioselective reduction of 3-substituted N-acylpyrazinium salts with n-Bu3SnH has been developed for the synthesis of 3-substituted 1,2-dihydropyrazines…”
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Paraphenylene dimers with diphenylamine donor groups: synthesis and photophysics by Le, Khoa, Chand, Lokendra B., Griffin, Colette, Williams, Alfred L., Taylor, Darlene K.

“…A novel paraphenylene dimer (D696) with electron donating diphenylamine side chain groups has been prepared. Optical absorption measurements were theoretically…”
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Microwave-assisted synthesis of 4-chloro- N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide (B-355252): a new potentiator of nerve growth factor (NGF)-induced neurite outgrowth by Williams, Alfred L., Dandepally, Srinivasa R., Gilyazova, Nailya, Witherspoon, Sam M., Ibeanu, Gordon

“…The synthesis of 4-chloro- N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide (B-355252) using an MW-assisted nucleophilic aromatic…”
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Identification of a Mg-protoporphyrin IX monomethyl ester cyclase homologue, EaZIP, differentially expressed in variegated Epipremnum aureum 'Golden Pothos' is achieved through a unique method of comparative study using tissue regenerated plants by Hung, Chiu-Yueh, Sun, Ying-Hsuan, Chen, Jianjun, Darlington, Diane E, Williams, Alfred L, Burkey, Kent O, Xie, Jiahua

“…Variegated plants provide a valuable tool for studying chloroplast biogenesis by allowing direct comparison between green and white/yellow sectors within the…”
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Schwartz reagent mediated synthesis of thiazolones and imidazolones from thiazolidine-2,4-diones and imidazolidine-2,4-diones by Dandepally, Srinivasa Reddy, Elgoummadi, Radouane, Williams, Alfred L.

“…A novel reduction/elimination method of thiazolidine-2,4-dione and imidazolidine-2,4-dione derivatives using Schwartz reagent to synthesize numerous…”
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A synthetic analog of verbenachalcone potentiates NGF-induced neurite outgrowth and enhances cell survival in neuronal cell models by Clement, Ceiléssia M., Dandepally, Srinivasa R., Williams, Alfred L., Ibeanu, Gordon C.

“…This study uses NeuroScreen-1 (NS-1) cells, a derivative of pheochromocytoma (PC12) cells, to examine neurite outgrowth induced by a novel synthetic…”
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Fire Services' Abilities to Fund Operations, Train Personnel, Respond to, and Mitigate a Terrorist Attack: A Qualitative Multiple-Case Study by Williams, Alfred Henry, V

“…The United States fire service has been at the apex of providing protective services to U.S. citizens since its inception in the mid-1700s. On September 11,…”
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Regioselective addition of Grignard reagents to N-acylpyrazinium salts: synthesis of substituted 1,2-dihydropyrazines and Δ5-2-oxopiperazines by St. Hilaire Valentine R, Hopkins, William E, Miller, Yenteeo S, Dandepally, Srinivasa R, Williams, Alfred L

“…The regioselective addition of Grignard reagents to mono- and disubstituted N-acylpyrazinium salts affording substituted 1,2-dihydropyrazines in modest to…”
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p-methoxybenzyl (PMB) protection/deprotection approach toward the synthesis of 5-phenoxy-4-chloro-N-(aryl/alkyl) thiophene-2-sulfonamides by Williams, Alfred L, Dandepally, Srinivasa R, Kotturi, Sharadsrikar V

“…The synthesis of 17 phenoxy substituted 4-chloro-N-(aryl/alkyl)thiophene-2-sulfonamides using a PMB protection/deprotection strategy is described. Nucleophilic…”
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Erythropoietin has a restorative effect on the contractility of arteries following experimental hypoxia by Withers, Sarah B., Passi, Neha, Williams, Alfred S., de Freitas, Declan, Heagerty, Anthony M.

“…The aim of this study was to investigate the effect of erythropoietin on vascular contractility using an in vitro model of hypoxia replicating the hypoxic…”
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Imperial, Neo-Liberal Africa? by Zack-Williams, Alfred B., Mohan, Giles

“…Discusses the millennium goals on poverty reduction within Third World countries, and outlines economic conditions in Africa. Adapted from the source document…”
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Sierra Leone: The political economy of civil war, 1991-98 by Zack-Williams, Alfred B

“…This article looks at the causal factors for the May 1997 military intervention in Sierra Leone which unleashed complex political emergencies engulfing the…”
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Tributes to Tajudeen Abdul-Raheem (1961-2009) by Zack-Williams, Alfred B., Abdullah, Ibrahim, Olonisakin, 'Funmi

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Information Systems and Business Communication by Beswick, Raymond W., Ed, Williams, Alfred B., Ed

“…Intended to provide orientation about the integration of business communication, business systems, and the researching and teaching of business communication,…”
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