Search Results - "Williams, A. S"
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Effects of Dilatant Hardening on Fault Stabilization and Structural Development
Published in Geophysical research letters (28-05-2024)“…Dilatant hardening is one proposed mechanism that causes slow earthquakes along faults. Previous experiments and models show that dilatant hardening can…”
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Comparative effectiveness and cardiovascular safety of abaloparatide and teriparatide in postmenopausal women new to anabolic therapy: A US administrative claims database study
Published in Osteoporosis international (01-08-2022)“…Mini abstract Real-world evidence on the comparative effectiveness and safety of abaloparatide versus teriparatide in women with osteoporosis may help inform…”
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3
Biomarkers and Surrogate End Points for Fit-for-Purpose Development and Regulatory Evaluation of New Drugs
Published in Clinical pharmacology and therapeutics (01-01-2007)“…A consistent framework for the acceptance and qualification of biomarkers for regulatory use is needed to facilitate innovative and efficient research and…”
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4
Osteoporotic fracture trends in a population of US managed care enrollees from 2007 to 2017
Published in Osteoporosis international (01-07-2020)“…Summary This study expands on previous findings that hip fracture rates may no longer be declining. We found that age- and sex-adjusted fracture rates in the…”
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Characterizing patients initiating abaloparatide, teriparatide, or denosumab in a real-world setting: a US linked claims and EMR database analysis
Published in Osteoporosis international (01-12-2020)“…Summary We characterized patients initiating abaloparatide (ABL), teriparatide (TPTD), or denosumab (DMAB) in a real-world clinical setting from a large…”
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Fixation in Form-Acetic allows hyaluronic acid detection in mouse ovaries
Published in Reproduction & fertility (30-12-2021)“…To visualise tissues to determine the presence of disease or simply to understand anatomy, it is important to preserve fresh tissue. Fixatives are chemical…”
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Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase‐9
Published in British journal of pharmacology (01-10-2012)“…BACKGROUND AND PURPOSE Excess morbidity/mortality in rheumatoid arthritis (RA) is associated with increased incidence of cardiovascular disease. In this…”
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Role of Rho kinase isoforms in murine allergic airway responses
Published in The European respiratory journal (01-10-2011)“…Inhibition of Rho-associated coiled-coil forming kinases (ROCKs) reduces allergic airway responses in mice. The purpose of this study was to determine the…”
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A Prototypical Process for Creating Evidentiary Standards for Biomarkers and Diagnostics
Published in Clinical pharmacology and therapeutics (01-02-2008)“…A framework for developing evidentiary standards for qualification of biomarkers is a key need identified in the Food and Drug Administration's Critical Path…”
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Dental therapy in the United Kingdom: part 2. A survey of reported working practices
Published in British dental journal (14-11-2009)“…Key Points Outlines the current working practices of dental therapists within the UK. Describes their geographic distribution, hours of work and work settings…”
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Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13
Published in The European respiratory journal (01-09-2008)“…The present study aimed to determine whether the T-helper cell type 2-derived cytokines, interleukin (IL)-4 and -13, can modulate the lung response to ozone…”
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Improved preservation of ovarian tissue morphology that is compatible with antigen detection using a fixative mixture of formalin and acetic acid
Published in Human reproduction (Oxford) (18-06-2021)“…Can ovarian tissue morphology be better preserved whilst enabling histological molecular analyses following fixation with a novel fixative, neutral buffered…”
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Dental therapy in the United Kingdom: part 4. Teamwork - is it working for dental therapists?
Published in British dental journal (12-12-2009)“…Key Points Investigates dental therapists' perspectives on teamwork within a range of clinical settings in the UK. Describes dental therapists' feelings of…”
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A TaqMan-based multiplex real-time PCR assay for the simultaneous detection of Wuchereria bancrofti and Brugia malayi
Published in Molecular and biochemical parasitology (01-05-2013)“…•We describe a multiplex real-time PCR assay to detect Wuchereria bancrofti and Brugia malayi.•The assay is comparably sensitive to the established singleplex…”
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Accuracy and precision of joint space width measurements in standard and macroradiographs of osteoarthritic knees
Published in Annals of the rheumatic diseases (01-11-1995)“…OBJECTIVES--To improve the reproducibility and accuracy of joint space width (JSW) measurement as an assessment of cartilage loss in patients with…”
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Abaloparatide for risk reduction of nonvertebral and vertebral fractures in postmenopausal women with osteoporosis: a network meta-analysis
Published in Osteoporosis international (01-07-2019)“…Summary This network meta-analysis assessed the efficacy of abaloparatide versus other treatment options to reduce the risk of fractures in women with…”
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Effect of nutritional supplementation on quantities of glucose transporters 1 and 4 in sheep granulosa and theca cells
Published in Reproduction (Cambridge, England) (01-12-2001)“…The stimulatory effect of nutritional supplementation on ovarian activity in sheep has been linked to an increase in glucose availability that, with insulin,…”
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Dental therapy in the United Kingdom: part 1. Developments in therapists' training and role
Published in British dental journal (24-10-2009)“…Key Points This paper outlines the history and development of dental therapy within the UK. It describes the recent expansion in the number of dental therapy…”
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Dental therapy in the United Kingdom: part 3. Financial aspects of current working practices
Published in British dental journal (28-11-2009)“…Key Points This paper presents the findings from a survey which looked at remuneration arrangements as reported by UK dental therapists. Many therapists were…”
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Post-operative recovery after inguinal herniotomy in ex-premature infants: comparison between sevoflurane and spinal anaesthesia
Published in British journal of anaesthesia : BJA (01-03-2001)“…We prospectively studied the post-operative recovery profile of 28 ex-premature infants undergoing inguinal herniotomy. All infants had a post-conceptual age…”
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