Search Results - "William S. Hayward"

Avian bic, a Gene Isolated from a Common Retroviral Site in Avian Leukosis Virus-Induced Lymphomas That Encodes a Noncoding RNA, Cooperates with c-myc in Lymphomagenesis and Erythroleukemogenesis by Tam, Wayne, Hughes, Stephen H, Hayward, William S, Besmer, Peter

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bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA by Tam, Wayne, Ben-Yehuda, Dina, Hayward, William S.

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Activation of a cellular onc gene by promoter insertion in ALV -induced lymphoid leukosis by Hayward, W.S, Neel, B.G, Astrin, S.M

“…Analyses of DNA and RNA from avian leukosis virus (ALV)-induced lymphomas have provided strong evidence that, in most tumours, ALV induces neoplastic disease…”
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Activation of a translocated human c- myc gene by an enhancer in the immunoglobulin heavy-chain locus by Hayday, Adrian C, Gillies, Stephen D, Saito, Haruo, Wood, Charles, Wiman, Klas, Hayward, William S, Tonegawa, Susumu

“…A tissue-specific transcriptional enhancer element that is associated with the human immunoglobulin heavy-chain locus is defined. In a non-Hodgkin's lymphoma…”
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Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion by Neel, B G, Hayward, W S, Robinson, H L, Fang, J, Astrin, S M

“…Unlike other RNA tumor viruses, avian leukosis viruses (which cause lymphomas and occasionally other neoplasms) lack discrete "transforming genes". We have…”
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Size and Genetic Content of Viral RNAs in Avian Oncovirus-Infected Cells by Hayward, W S

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Endogenous viral genes are non-essential in the chicken by Astrin, Susan M, Buss, Edward G, Hayward, William S

“…DNA sequences homologous to the genomes of type C retroviruses are widespread among vertebrates. Ten genetic loci containing endogenous viral DNA sequences…”
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Genetic Variation in the RNA Transcripts of Endogenous Virus Genes in Uninfected Chicken Cells by Wang, S Y, Hayward, W S, Hanafusa, H

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Detection of Avian Tumor Virus RNA in Uninfected Chicken Embryo Cells by Hayward, W S, Hanafusa, H

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Effect of the Lambda Repressor on the Binding of RNA Polymerase to DNA by Hayward, William S., Green, Melvin H.

“…Experiments were designed with the aim of understanding the mechanism whereby the lambda repressor inhibits messenger RNA synthesis. Complexes containing…”
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Minimal truncation of the c-myb gene product in rapid-onset B-cell lymphoma by Jiang, W, Kanter, M R, Dunkel, I, Ramsay, R G, Beemon, K L, Hayward, W S

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Genetic determinant of rapid-onset B-cell lymphoma by avian leukosis virus by Smith, M.R. (Fox Chase Cancer Center, Philadelphia, PA.), Smith, R.E, Dunkel, I, Hou, V, Beemon, K.L, Hayward, W.S

“…Infection of 10 day-old chicken embryos with the recombinant avian leukosis virus (ALV) EU-8 induces a high incidence of rapid-onset B-cell lymphoma by…”
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The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles by SPENCER, C. A, LESTRANGE, R. C, NOVAK, U, HAYWARD, W. S, GROUDINE, M

“…Aberrant c-myc expression patterns occur in human Burkitt's lymphoma cells, which consistently exhibit c-myc chromosomal translocations, mutations within and…”
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Activation of the C-myc Gene by Translocation: A Model for Translational Control by Saito, Haruo, Hayday, Adrian C., Wiman, Klas, Hayward, William S., Tonegawa, Susumu

“…We have shown that the human cellular oncogene c-myc is composed of three exons and is transcribed from two initiation sites separated by 175-base-pair DNA in…”
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Two Human c-onc Genes are Located on the Long Arm of Chromosome 8 by Neel, Benjamin G., Jhanwar, Suresh C., Chaganti, R. S. K., Hayward, William S.

“…We have used in situ chromosome hybridization techniques to map the human cellular counterparts (c-onc genes) of the transforming genes of two RNA tumor…”
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Absence of Missense Mutations in Activated c-myc Genes in Avian Leukosis Virus-Induced B-Cell Lymphomas by Hahn, Mounou, Hayward, William S.

“…We have determined the nucleotide sequences of two independent DNA clones which contained the activated c-myc genes from avian leukosis virus-induced B-cell…”
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Localization of c-ras Oncogene Family on Human Germ-Line Chromosomes by Jhanwar, Suresh C., Neel, Benjamin G., Hayward, William S., Chaganti, R. S. K.

“…The c-ras family is a set of c-onc genes that are highly conserved in vertebrates. The genes in this family are homologous to the transforming genes of Harvey…”
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Activation of a Translocated c-myc Gene: Role of Structural Alterations in the Upstream Region by Wiman, Klas G., Clarkson, Bayard, Hayday, Adrian C., Saito, Haruo, Tonegawa, Susumu, Hayward, William S.

“…The translocated c-myc gene in AW-Ramos, a Burkitt lymphoma cell line carrying the 8;14 translocation, is expressed at 2- to 5-fold higher levels than c-myc in…”
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Nucleotide Sequence 5′of the Chicken c-myc Coding Region: Localization of a Noncoding Exon That is Absent from myc Transcripts in Most Avian Leukosis Virus-Induced Lymphomas by Shih, Cheng-Kon, Linial, Maxine, Goodenow, Maureen M., Hayward, William S.

“…We have determined the nucleotide sequence of the 2.2-kilobase-pair region upstream of the chicken c-myc coding exons. Using RNA blot analysis, we have…”
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Multiple Proto-Oncogene Activations in Avian Leukosis Virus- Induced Lymphomas: Evidence for Stage-Specific Events by Clurman, Bruce E., Hayward, William S.

“…We have examined avian leukosis virus-induced B-cell lymphomas for multiple, stage-specific oncogene activations. Three targets for viral integration were…”
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