Search Results - "William N. Green"

Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction by Govind, Anitha P., Vezina, Paul, Green, William N.

“…Potential mechanisms underlying nicotine-induced upregulation of nAChRs. A major hurdle in defining the molecular biology of nicotine addiction has been…”
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Editorial: Role of protein palmitoylation in synaptic plasticity and neuronal differentiation, volume II by Koster, Kevin P, Green, William N

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Palmitoylation regulates glutamate receptor distributions in postsynaptic densities through control of PSD95 conformation and orientation by Jeyifous, Okunola, Lin, Eric I., Chen, Xiaobing, Antinone, Sarah E., Mastro, Ryan, Drisdel, Renaldo, Reese, Thomas S., Green, William N.

“…Postsynaptic density protein 95 (PSD95) and synapse-associated protein 97 (SAP97) are homologous scaffold proteins with different N-terminal domains,…”
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RNA-based translation activators for targeted gene upregulation by Cao, Yang, Liu, Huachun, Lu, Shannon S., Jones, Krysten A., Govind, Anitha P., Jeyifous, Okunola, Simmons, Christine Q., Tabatabaei, Negar, Green, William N., Holder, Jimmy. L., Tahmasebi, Soroush, George, Alfred L., Dickinson, Bryan C.

“…Technologies capable of programmable translation activation offer strategies to develop therapeutics for diseases caused by insufficient gene expression. Here,…”
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Global Analysis of Protein Palmitoylation in Yeast by Roth, Amy F., Wan, Junmei, Bailey, Aaron O., Sun, Beimeng, Kuchar, Jason A., Green, William N., Phinney, Brett S., Yates, John R., Davis, Nicholas G.

“…Protein palmitoylation is a reversible lipid modification that regulates membrane tethering for key proteins in cell signaling, cancer, neuronal transmission,…”
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SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway by Lin, Eric I, Green, William N, Specht, Christian G, Jeyifous, Okunola, Waites, Clarissa L, Marshall, John, Garner, Craig C, Schubert, Manja, de Silva, Tharani, Aoki, Chiye, Montgomery, Johanna M, Fujisawa, Sho

“…This study shows that, although AMPA-type glutamate receptors are trafficked to dendrites through the normal Golgi secretory pathway, NMDA receptors bypass the…”
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Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice by Zammit, Matthew, Kao, Chien-Min, Zhang, Hannah J, Tsai, Hsiu-Ming, Holderman, Nathanial, Mitchell, Samuel, Tanios, Eve, Bhuiyan, Mohammed, Freifelder, Richard, Kucharski, Anna, Green, William N, Mukherjee, Jogeshwar, Chen, Chin-Tu

“…Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the…”
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Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes by Lee, Sang Hak, Jin, Chaoyi, Cai, En, Ge, Pinghua, Ishitsuka, Yuji, Teng, Kai Wen, de Thomaz, Andre A, Nall, Duncan, Baday, Murat, Jeyifous, Okunola, Demonte, Daniel, Dundas, Christopher M, Park, Sheldon, Delgado, Jary Y, Green, William N, Selvin, Paul R

“…Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we…”
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Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome by Govind, Anitha P, Jeyifous, Okunola, Russell, Theron A, Yi, Zola, Weigel, Aubrey V, Ramaprasad, Abhijit, Newell, Luke, Ramos, William, Valbuena, Fernando M, Casler, Jason C, Yan, Jing-Zhi, Glick, Benjamin S, Swanson, Geoffrey T, Lippincott-Schwartz, Jennifer, Green, William N

“…Activity-driven changes in the neuronal surface glycoproteome are known to occur with synapse formation, plasticity, and related diseases, but their…”
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Labeling and quantifying sites of protein palmitoylation by Drisdel, Renaldo C, Green, William N

“…As a reversible posttranslational modification, protein palmitoylation has the potential to regulate the trafficking and function of a variety of proteins…”
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Synaptic activity regulates AMPA receptor trafficking through different recycling pathways by Zheng, Ning, Jeyifous, Okunola, Munro, Charlotte, Montgomery, Johanna M, Green, William N

“…Changes in glutamatergic synaptic strength in brain are dependent on AMPA-type glutamate receptor (AMPAR) recycling, which is assumed to occur through a single…”
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Stable Small Quantum Dots for Synaptic Receptor Tracking on Live Neurons by Cai, En, Ge, Pinghua, Lee, Sang Hak, Jeyifous, Okunola, Wang, Yong, Liu, Yanxin, Wilson, Katie M., Lim, Sung Jun, Baird, Michelle A., Stone, John E., Lee, Kwan Young, Davidson, Michael W., Chung, Hee Jung, Schulten, Klaus, Smith, Andrew M., Green, William N., Selvin, Paul R.

“…We developed a coating method to produce functionalized small quantum dots (sQDs), about 9 nm in diameter, that were stable for over a month. We made sQDs in…”
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Palmitoylation of huntingtin by HIP14is essential for its trafficking and function by Yanai, Anat, Huang, Kun, Kang, Rujun, Singaraja, Roshni R, Arstikaitis, Pamela, Gan, Lu, Orban, Paul C, Mullard, Asher, Cowan, Catherine M, Raymond, Lynn A, Drisdel, Renaldo C, Green, William N, Ravikumar, Brinda, Rubinsztein, David C, El-Husseini, Alaa, Hayden, Michael R

“…Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Here we show that huntingtin (htt)…”
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Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation by Govind, Anitha P, Vallejo, Yolanda F, Stolz, Jacob R, Yan, Jing-Zhi, Swanson, Geoffrey T, Green, William N

“…To better understand smoking cessation, we examined the actions of varenicline (Chantix) during long-term nicotine exposure. Varenicline reduced nicotine…”
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Up-regulation of Nicotinic Receptors by Nicotine Varies with Receptor Subtype by Walsh, Heather, Govind, Anitha P., Mastro, Ryan, Hoda, J.C., Bertrand, Daniel, Vallejo, Yolanda, Green, William N.

“…Recent evidence suggests that in addition to α4β2 and α3-containing nicotinic receptors, α6-containing receptors are present in midbrain dopaminergic neurons…”
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Synaptic SAP97 Isoforms Regulate AMPA Receptor Dynamics and Access to Presynaptic Glutamate by Waites, Clarissa L, Specht, Christian G, Hartel, Kai, Leal-Ortiz, Sergio, Genoux, David, Li, Dong, Drisdel, Renaldo C, Jeyifous, Okun, Cheyne, Juliette E, Green, William N, Montgomery, Johanna M, Garner, Craig C

“…The synaptic insertion of GluR1-containing AMPA-type glutamate receptors (AMPARs) is critical for synaptic plasticity. However, mechanisms responsible for…”
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Regulation of nicotinic receptor expression by the ubiquitin-proteasome system by Christianson, John C, Green, William N

“…Control of ligand‐gated ion channel (LGIC) expression is essential for the formation, maintenance and plasticity of synapses. Treatment of mouse myotubes with…”
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Endoplasmic Reticulum Chaperones Stabilize Nicotinic Receptor Subunits and Regulate Receptor Assembly by Wanamaker, Christian P., Green, William N.

“…We examined interactions between the endoplasmic reticulum (ER) chaperones calnexin (CN), ERp57, and immunological heavy chain-binding protein (BiP) and…”
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Palmitoylation of ATP-Binding Cassette Transporter A1 Is Essential for Its Trafficking and Function by Singaraja, Roshni R, Kang, Martin H, Vaid, Kuljeet, Sanders, Shaun S, Vilas, Gonzalo L, Arstikaitis, Pamela, Coutinho, Jonathan, Drisdel, Renaldo C, El Din El-Husseini, Alaa, Green, William N, Berthiaume, Luc, Hayden, Michael R

“…ATP-binding cassette transporter (ABC)A1 lipidates apolipoprotein A-I both directly at the plasma membrane and also uses lipids from the late endosomal or…”
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Regulation of Nicotinic Acetylcholine Receptor Assembly by WANAMAKER, CHRISTIAN P., CHRISTIANSON, JOHN C., GREEN, WILLIAM N.

“…: The four muscle‐type nicotinic acetylcholine receptor (AChR) subunits, α, β, γ, and δ, assemble into functional α2βγδ pentamers in the endoplasmic reticulum…”
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