Search Results - "William Chapman, G"

Neuronal representation of environmental boundaries in egocentric coordinates by Hinman, James R., Chapman, G. William, Hasselmo, Michael E.

“…Movement through space is a fundamental behavior for all animals. Cognitive maps of environments are encoded in the hippocampal formation in an allocentric…”
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Egocentric boundary vector tuning of the retrosplenial cortex by Alexander, Andrew S, Carstensen, Lucas C, Hinman, James R, Raudies, Florian, Chapman, G William, Hasselmo, Michael E

“…The retrosplenial cortex is reciprocally connected with multiple structures implicated in spatial cognition, and damage to the region itself produces numerous…”
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Head direction is coded more strongly than movement direction in a population of entorhinal neurons by Raudies, Florian, Brandon, Mark P, Chapman, G. William, Hasselmo, Michael E

“…Abstract The spatial firing pattern of entorhinal grid cells may be important for navigation. Many different computational models of grid cell firing use path…”
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Post-Inhibitory Rebound Spikes in Rat Medial Entorhinal Layer II/III Principal Cells: In Vivo, In Vitro, and Computational Modeling Characterization by Ferrante, Michele, Shay, Christopher F, Tsuno, Yusuke, William Chapman, G, Hasselmo, Michael E

“…Medial entorhinal cortex Layer-II stellate cells (mEC-LII-SCs) primarily interact via inhibitory interneurons. This suggests the presence of alternative…”
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Adaptive integration of self-motion and goals in posterior parietal cortex by Alexander, Andrew S., Tung, Janet C., Chapman, G. William, Conner, Allison M., Shelley, Laura E., Hasselmo, Michael E., Nitz, Douglas A.

“…Rats readily switch between foraging and more complex navigational behaviors such as pursuit of other rats or prey. These tasks require vastly different…”
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Systemic administration of two different anxiolytic drugs decreases local field potential theta frequency in the medial entorhinal cortex without affecting grid cell firing fields by Monaghan, Caitlin K., Chapman, G. William, Hasselmo, Michael E.

“…•Anxiolytic drugs reduce local field potential theta frequency in the medial entorhinal cortex.•The intercept, and not the slope, of the linear fit to theta…”
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Rebound spiking in layer II medial entorhinal cortex stellate cells: Possible mechanism of grid cell function by Shay, Christopher F., Ferrante, Michele, Chapman, G. William, Hasselmo, Michael E.

“…•We tested rebound spiking properties in medial entorhinal cortex stellate cells.•Hyperpolarizing inputs eliciting rebound spikes occur in a specific phase…”
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Neural responses in retrosplenial cortex associated with environmental alterations by Carstensen, Lucas C., Alexander, Andrew S., Chapman, G. William, Lee, Aubrey J., Hasselmo, Michael E.

“…The retrosplenial cortex (RSC) is an area interconnected with regions of the brain that display spatial correlates. Neurons in connected regions may encode an…”
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Gray & white matter tissue contrast differentiates Mild Cognitive Impairment converters from non-converters by Jefferson, Angela L., Gifford, Katherine A., Damon, Stephen, Chapman, G. William, Liu, Dandan, Sparling, Jamie, Dobromyslin, Vitaly, Salat, David

“…The clinical relevance of gray/white matter contrast ratio (GWR) in mild cognitive impairment (MCI) remains unknown. This study examined baseline GWR and…”
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Subjective memory complaint only relates to verbal episodic memory performance in mild cognitive impairment by Gifford, Katherine A, Liu, Dandan, Damon, Stephen M, Chapman, 4th, William G, Romano Iii, Raymond R, Samuels, Lauren R, Lu, Zengqi, Jefferson, Angela L

“…A cognitive concern from the patient, informant, or clinician is required for the diagnosis of mild cognitive impairment (MCI); however, the cognitive and…”
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Predictive learning by a burst-dependent learning rule by Chapman, G. William, Hasselmo, Michael E.

“…Humans and other animals are able to quickly generalize latent dynamics of spatiotemporal sequences, often from a minimal number of previous experiences…”
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Neurophysiological coding of space and time in the hippocampus, entorhinal cortex, and retrosplenial cortex by Alexander, Andrew S., Robinson, Jennifer C., Dannenberg, Holger, Kinsky, Nathaniel R., Levy, Samuel J., Mau, William, Chapman, G. William, Sullivan, David W., Hasselmo, Michael E.

“…Neurophysiological recordings in behaving rodents demonstrate neuronal response properties that may code space and time for episodic memory and goal-directed…”
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The Unexplored Territory of Neural Models: Potential Guides for Exploring the Function of Metabotropic Neuromodulation by Hasselmo, Michael E., Alexander, Andrew S., Hoyland, Alec, Robinson, Jennifer C., Bezaire, Marianne J., Chapman, G. William, Saudargiene, Ausra, Carstensen, Lucas C., Dannenberg, Holger

“…•Neural network models fail to incorporate many dimensions of physiological function regulated by metabotropic receptors.•Enumeration of the dimensions of…”
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Multiple Running Speed Signals in Medial Entorhinal Cortex by Hinman, James R., Brandon, Mark P., Climer, Jason R., Chapman, G. William, Hasselmo, Michael E.

“…Grid cells in medial entorhinal cortex (MEC) can be modeled using oscillatory interference or attractor dynamic mechanisms that perform path integration, a…”
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Military Mental Health: The Role of Daily Hassles While Deployed by Heron, Elizabeth A, Bryan, Craig J, Dougherty, Craig A, Chapman, William G

“…ABSTRACTThis study sought to identify factors contributing to symptoms of depression and posttraumatic stress disorder (PTSD) in recently deployed combat…”
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Oxaliplatin-induced damage of cellular DNA by Woynarowski, J M, Faivre, S, Herzig, M C, Arnett, B, Chapman, W G, Trevino, A V, Raymond, E, Chaney, S G, Vaisman, A, Varchenko, M, Juniewicz, P E

“…Damage to cellular DNA is believed to determine the antiproliferative properties of platinum (Pt) drugs. This study characterized DNA damage by oxaliplatin, a…”
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Sequence- and region-specificity of oxaliplatin adducts in naked and cellular DNA by Woynarowski, J M, Chapman, W G, Napier, C, Herzig, M C, Juniewicz, P

“…Oxaliplatin is a clinical anticancer drug with a pharmacological profile distinct from that of cisplatin. Our studies compared site- and region-specificity of…”
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Biological Dynamics Enabling Training of Binary Recurrent Networks by Chapman, G. William, Teeter, Corinne, Agarwal, Sapan, Xiao, T. Patrick, Hays, Park, Musuvathy, Srideep S.

“…Neuromorphic computing systems have been used for the processing of spatiotemporal video-like data, requiring the use of recurrent networks, while attempting…”
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A Model of Relational Reasoning Through Selective Attention by Chapman, G William

“…Understanding the relationship between sets of objects is a fundamental requirement of cognitive skills, such as learning from example or generalization. For…”
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Towards Biologically Plausible Mechanisms of Predictive Learning by Chapman, G. William

“…Animals perform a myriad of behaviors such as object tracking and spatial navigation, primarily in the absence of explicit target signals. In the absence of…”
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