Search Results - "William, Stenson"

Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells by Riehl, Terrence E, Alvarado, David, Ee, Xueping, Zuckerman, Aaron, Foster, Lynn, Kapoor, Vaishali, Thotala, Dinesh, Ciorba, Matthew A, Stenson, William F

“…GG (LGG), a probiotic, given by gavage is radioprotective of the mouse intestine. LGG-induced radioprotection is toll-like receptor 2 (TLR2) and…”
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The universe of arachidonic acid metabolites in inflammatory bowel disease: can we tell the good from the bad? by Stenson, William F

“…PURPOSE OF REVIEWThis review summarizes recent developments in the role of soluble mediators of inflammation, particularly arachidonic acid metabolites, in…”
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Nonmicrobial Activation of TLRs Controls Intestinal Growth, Wound Repair, and Radioprotection by Stenson, William F, Ciorba, Matthew A

“…TLRs, key components of the innate immune system, recognize microbial molecules. However, TLRs also recognize some nonmicrobial molecules. In particular, TLR2…”
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Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner by Ciorba, Matthew A, Riehl, Terrence E, Rao, M Suprada, Moon, Clara, Ee, Xueping, Nava, Gerardo M, Walker, Monica R, Marinshaw, Jeffrey M, Stappenbeck, Thaddeus S, Stenson, William F

“…The small intestinal epithelium is highly sensitive to radiation and is a major site of injury during radiation therapy and environmental overexposure. To…”
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TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells by Luo, Jialie, Qian, Aihua, Oetjen, Landon K., Yu, Weihua, Yang, Pu, Feng, Jing, Xie, Zili, Liu, Shenbin, Yin, Shijin, Dryn, Dari, Cheng, Jizhong, Riehl, Terrence E., Zholos, Alexander V., Stenson, William F., Kim, Brian S., Hu, Hongzhen

“…Intestinal macrophages are critical for gastrointestinal (GI) homeostasis, but our understanding of their role in regulating intestinal motility is incomplete…”
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Hyaluronic Acid Binding to TLR4 Promotes Proliferation and Blocks Apoptosis in Colon Cancer by Makkar, Sarbjeet, Riehl, Terrence E, Chen, Baosheng, Yan, Yan, Alvarado, David M, Ciorba, Matthew A, Stenson, William F

“…Hyaluronic acid (HA), a constituent of the extracellular matrix, promotes colorectal cancer growth. CD44 is a relevant HA receptor in this context. However, HA…”
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Preventing necrotising enterocolitis with amniotic fluid stem cells by Stenson, William F

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Regulation of Colonic Epithelial Repair in Mice by Toll-Like Receptors and Hyaluronic Acid by Zheng, Ling, Riehl, Terrence E, Stenson, William F

“…Background & Aims The protective component of the host response to dextran sodium sulfate (DSS)-induced colitis in the mouse is mediated through the activation…”
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IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice by Thaker, Ameet I, Rao, M. Suprada, Bishnupuri, Kumar S, Kerr, Thomas A, Foster, Lynne, Marinshaw, Jeffrey M, Newberry, Rodney D, Stenson, William F, Ciorba, Matthew A

“…Background & Aims Indoleamine 2,3 dioxygenase-1 (IDO1) catabolizes tryptophan along the kynurenine pathway. Although IDO1 is expressed in inflamed and…”
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CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice by Riehl, Terrence E, Santhanam, Srikanth, Foster, Lynne, Ciorba, Matthew, Stenson, William F

“…Hyaluronic acid, a glycosaminoglycan in the extracellular matrix, binds to CD44 and Toll-like receptor 4 (TLR4). We previously addressed the role of hyaluronic…”
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The Hyaluronic Acid Receptor CD44 Coordinates Normal and Metaplastic Gastric Epithelial Progenitor Cell Proliferation by Khurana, Shradha S., Riehl, Terrence E., Moore, Benjamin D., Fassan, Matteo, Rugge, Massimo, Romero-Gallo, Judith, Noto, Jennifer, Peek, Richard M., Stenson, William F., Mills, Jason C.

“…The stem cell in the isthmus of gastric units continually replenishes the epithelium. Atrophy of acid-secreting parietal cells (PCs) frequently occurs during…”
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CD36‐dependent signaling mediates fatty acid‐induced gut release of secretin and cholecystokinin by Sundaresan, Sinju, Shahid, Rafiq, Riehl, Terrence E., Chandra, Rashmi, Nassir, Fatiha, Stenson, William F., Liddle, Rodger A., Abumrad, Nada A.

“…Genetic variants in the fatty acid (FA) translocase FAT/CD36 associate with abnormal postprandial lipids and influence risk for the metabolic syndrome. CD36 is…”
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Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse by Schill, Ellen Merrick, Lake, Jonathan I., Tusheva, Olga A., Nagy, Nandor, Bery, Saya K., Foster, Lynne, Avetisyan, Marina, Johnson, Stephen L., Stenson, William F., Goldstein, Allan M., Heuckeroth, Robert O.

“…Hirschsprung Disease (HSCR) is a potentially deadly birth defect characterized by the absence of the enteric nervous system (ENS) in distal bowel. Although…”
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Hyaluronic acid promotes Lgr5 + stem cell proliferation and crypt fission through TLR4 and PGE 2 transactivation of EGFR by Riehl, Terrence E, Alvarado, David, Ee, Xueping, Ciorba, Matthew A, Stenson, William F

“…Hyaluronic acid (HA), a glycosaminoglycan in the extracellular matrix, binds to CD44 and Toll-like receptor 4 (TLR4). We previously demonstrated that both CD44…”
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Hyaluronic acid regulates normal intestinal and colonic growth in mice by Riehl, Terrence E, Ee, Xueping, Stenson, William F

“…Hyaluronic acid (HA), a component of the extracellular matrix, affects gastrointestinal epithelial proliferation in injury models, but its role in normal…”
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Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism by Riehl, Terrence E, Foster, Lynne, Stenson, William F

“…The intestinal epithelium is sensitive to radiation injury. Damage to the intestinal epithelium is dose limiting in radiation therapy of abdominal cancers…”
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Variation in Treatment of Patients With Inflammatory Bowel Diseases at Major Referral Centers in the United States by Ananthakrishnan, Ashwin N, Kwon, Jennifer, Raffals, Laura, Sands, Bruce, Stenson, William F, McGovern, Dermot, Kwon, John H, Rheaume, Robert L, Sandler, Robert S

“…We performed a prospective study of patients with inflammatory bowel diseases to examine variations in treatment among medical centers. In a prospective cohort…”
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Serum analysis of tryptophan catabolism pathway: Correlation with Crohn's disease activity by Gupta, Nitin K., Thaker, Ameet I., Kanuri, Navya, Riehl, Terrence E., Rowley, Christopher W., Stenson, William F., Ciorba, Matthew A.

“…Background: Indoleamine 2,3 dioxygenase‐1 (IDO1) is a tryptophan catabolizing enzyme with immunotolerance‐promoting functions. We sought to determine if…”
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Prostaglandins and epithelial response to injury by Stenson, William F

“…PURPOSE OF REVIEWThis review will highlight recent studies in the role of prostaglandins in regulating the epithelial response to injury in the…”
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Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice by Shen, Yi, Ma, Jun, Yan, Ruilan, Ling, Hongyan, Li, Xiaoning, Yang, Wancai, Gao, John, Huang, Chenfei, Bu, Yiwen, Cao, Yu, He, Yingchun, Wan, Laxiang, Zu, Xuyu, Liu, Jianghua, Huang, Mei Chris, Stenson, William F, Liao, Duan-Fang, Cao, Deliang

“…Ulcerative colitis and colitis-associated colorectal cancer (CAC) is a serious health issue, but etiopathological factors remain unclear. Aldo-keto reductase…”
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