Search Results - "Willette, A A"
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Using machine learning to predict COVID-19 infection and severity risk among 4510 aged adults: a UK Biobank cohort study
Published in Scientific reports (11-05-2022)“…Many risk factors have emerged for novel 2019 coronavirus disease (COVID-19). It is relatively unknown how these factors collectively predict COVID-19…”
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Neuronal Pentraxin 2 Predicts Medial Temporal Atrophy and Memory Decline Across the Alzheimer’s Disease Spectrum
Published in Brain, behavior, and immunity (01-11-2016)“…Abstract Chronic neuroinflammation is thought to potentiate medial temporal lobe (MTL) atrophy and memory decline in Alzheimer’s disease (AD). It has become…”
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Does metabolic syndrome impact cognition and emotion in Alzheimer's disease?
Published in European journal of neurology (01-02-2016)“…Click here to view the accompanying paper in this issue…”
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Insulin resistance predicts medial temporal hypermetabolism in mild cognitive impairment conversion to Alzheimer disease
Published in Diabetes (New York, N.Y.) (01-06-2015)“…Alzheimer disease (AD) is characterized by progressive hypometabolism on [(18)F]-fluorodeoxyglucose positron emission tomography (FDG-PET) scans. Peripheral…”
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Serology and Alzheimer’s disease: Is infectious disease in the driver’s seat?
Published in Brain, behavior, and immunity (01-01-2025)Get full text
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Impact of COVID‐19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research
Published in Alzheimer's & dementia (01-05-2022)“…COVID‐19 causes lasting neurological symptoms in some survivors. Like other infections, COVID‐19 may increase risk of cognitive impairment. This perspective…”
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Posteromedial cortex glutamate and GABA predict intrinsic functional connectivity of the default mode network
Published in NeuroImage (Orlando, Fla.) (01-01-2013)“…The balance between excitatory glutamatergic projection neurons and inhibitory GABAergic interneurons determines the function of cortical microcircuits. How…”
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Inflammation, negative affect, and amyloid burden in Alzheimer’s disease: Insights from the kynurenine pathway
Published in Brain, behavior, and immunity (01-07-2021)“…•Higher Kyn/Trytophan and Kyn/5-HT were linked to poorer memory, executive function, and global cognition.•A higher Kyn/5-HT ratio was linked to less gray…”
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Vitamin B6, B12, and Folate's Influence on Neural Networks in the UK Biobank Cohort
Published in Nutrients (01-07-2024)“…One-carbon metabolism coenzymes may influence brain aging in cognitively unimpaired adults. Baseline data were used from the UK Biobank cohort. Estimated…”
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Insulin resistance predicts brain amyloid deposition in late middle-aged adults
Published in Alzheimer's & dementia (01-05-2015)“…Abstract Background Insulin resistance (IR) increases Alzheimer's disease (AD) risk. IR is related to greater amyloid burden post-mortem and increased…”
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A machine learning approach for potential Super‐Agers identification using neuronal functional connectivity networks
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-04-2024)“…INTRODUCTION Aging is often associated with cognitive decline. Understanding neural factors that distinguish adults in midlife with superior cognitive…”
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Insulin Resistance, Brain Atrophy, and Cognitive Performance in Late Middle―Aged Adults
Published in Diabetes care (01-02-2013)“…Insulin resistance dysregulates glucose uptake and other functions in brain areas affected by Alzheimer disease. Insulin resistance may play a role in…”
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Autotaxin is Related to Metabolic Dysfunction and Predicts Alzheimer's Disease Outcomes
Published in Journal of Alzheimer's disease (01-01-2017)“…Obesity and insulin resistance are associated with neuropathology and cognitive decline in Alzheimer's disease (AD). Ecto-nucleotide…”
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A Systematic Review and Meta-Analysis of Diagnostic Screening Criteria for Blunt Cerebrovascular Injuries
Published in Journal of the American College of Surgeons (01-03-2012)“…Background Despite progress in diagnosing and managing blunt cerebrovascular injury (BCVI), controversy remains regarding the appropriate population to screen…”
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Alzheimer's Disease Genetic Influences Impact the Associations between Diet and Resting-State Functional Connectivity: A Study from the UK Biobank
Published in Nutrients (30-07-2023)“…Red wine and dairy products have been staples in human diets for a long period. However, the impact of red wine and dairy intake on brain network activity…”
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Aging Modifies the Effect of GCH1 RS11158026 on DAT Uptake and Parkinson's Disease Clinical Severity
Published in Neurobiology of aging (01-02-2017)“…Abstract Novel single nucleotide polymorphisms within Parkinson’s disease (PD) can predict disease risk, but their influence on clinical, cognitive and…”
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Detection of pathogens in blood or feces of adult horses with enteric disease and association with outcome of colitis
Published in Journal of veterinary internal medicine (01-09-2021)“…Background Rates of detecting ≥1 potential enteric pathogens (PEP) or toxins (PEP‐T) in feces, blood, or both of horses ≥6 months of age with enteric disease…”
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Abstract # 1783 Metabolic dysfunction, inflammation, and task-induced emotional stress reactivity: Neural and cognitive correlates in 331 middle-aged adults
Published in Brain, behavior, and immunity (01-10-2016)“…Pre-diabetes and type 2 diabetes (T2D) etiology is characterized by insulin resistance (IR) and systemic inflammation. These factors can cause deficits in…”
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Abstract # 1784 Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer’s disease spectrum
Published in Brain, behavior, and immunity (01-10-2016)“…Neuroinflammation is thought to potentiate medial temporal lobe (MTL) atrophy and memory decline in Alzheimer’s disease (AD). It has become increasingly…”
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The Tropical Seagrass Halophila stipulacea: Reviewing What We Know From Its Native and Invasive Habitats, Alongside Identifying Knowledge Gaps
Published in Frontiers in Marine Science (26-05-2020)“…Halophila stipulacea is a small tropical seagrass, native to the Red Sea, Persian Gulf, and the Indian Ocean. It invaded the Mediterranean Sea 150 years ago as…”
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