Search Results - "Willerth, Stephanie Michelle"
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Mechanically stable fibrin scaffolds promote viability and induce neurite outgrowth in neural aggregates derived from human induced pluripotent stem cells
Published in Scientific reports (24-07-2017)“…Recent work demonstrated that 3D fibrin scaffolds function as an effective substrate for engineering tissues from pluripotent stem cells. However, the rapid…”
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Extrusion and Microfluidic‐Based Bioprinting to Fabricate Biomimetic Tissues and Organs
Published in Advanced materials technologies (01-08-2020)“…Next generation engineered tissue constructs with complex and ordered architectures aim to better mimic the native tissue structures, largely due to advances…”
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3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based Bioink
Published in Biomolecules (Basel, Switzerland) (21-08-2021)“…Current treatments for neurodegenerative diseases aim to alleviate the symptoms experienced by patients; however, these treatments do not cure the disease nor…”
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Localized Tacrolimus Delivery Repairs the Damaged Central Nervous System
Published in EBioMedicine (01-12-2017)Get full text
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Characterizing the Mechanical Performance of a Bare-Metal Stent with an Auxetic Cell Geometry
Published in Applied sciences (01-01-2022)“…This study develops and characterizes the distinctive mechanical features of a stainless-steel metal stent with a tailored structure. A high-precision…”
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Editorial: Stem Cell Systems Bioengineering
Published in Frontiers in bioengineering and biotechnology (07-05-2021)Get full text
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How can microsphere-mediated delivery of small molecules serve as a novel tool for engineering tissues from stem cells?
Published in Therapeutic delivery (01-11-2019)Get full text
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CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury
Published in Molecular neurobiology (01-04-2020)“…Spinal cord injury (SCI) causes temporary disabilities or permanent effects including neuropathic pain and spastiscity. The damage often results from…”
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Functionalizing Ascl1 with Novel Intracellular Protein Delivery Technology for Promoting Neuronal Differentiation of Human Induced Pluripotent Stem Cells
Published in Stem cell reviews (01-08-2016)“…Pluripotent stem cells can become any cell type found in the body. Accordingly, one of the major challenges when working with pluripotent stem cells is…”
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Controlled release of glial cell line-derived neurotrophic factor from poly(ε-caprolactone) microspheres
Published in Drug delivery and translational research (01-04-2014)“…Glial cell line-derived neurotrophic factor (GDNF), a growth factor expressed in the central nervous system, promotes the survival of both dopaminergic and…”
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Engineering Neural Tissue from Human Pluripotent Stem Cells Using Novel Small Molecule Releasing Microspheres
Published in Advanced biosystems (01-12-2018)“…Here a novel technique for engineering neural tissue consisting of motor neurons by combining human‐induced pluripotent stem cells (hiPSCs) with small…”
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The effect of controlled delivery of growth factors on embryonic stem cell differentiation inside of fibrin scaffolds
Published 01-01-2008“…The goal of this thesis was to develop novel biomaterial scaffolds for the treatment of spinal cord injury. Fibrin was chosen as the scaffold material due to…”
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Dissertation -
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The effect of controlled delivery of growth factors on embryonic stem cell differentiation inside of fibrin scaffolds
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Dissertation