Search Results - "Willers, Maike"

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants by Willers, Maike, Ulas, Thomas, Völlger, Lena, Vogl, Thomas, Heinemann, Anna S., Pirr, Sabine, Pagel, Julia, Fehlhaber, Beate, Halle, Olga, Schöning, Jennifer, Schreek, Sabine, Löber, Ulrike, Essex, Morgan, Hombach, Peter, Graspeuntner, Simon, Basic, Marijana, Bleich, Andre, Cloppenborg-Schmidt, Katja, Künzel, Sven, Jonigk, Danny, Rupp, Jan, Hansen, Gesine, Förster, Reinhold, Baines, John F., Härtel, Christoph, Schultze, Joachim L., Forslund, Sofia K., Roth, Johannes, Viemann, Dorothee

“…After birth, the immune system matures via interactions with microbes in the gut. The S100 calcium binding proteins S100A8 and S100A9, and their extracellular…”
Get full text

Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice by Perruzza, Lisa, Heckmann, Julia, Rezzonico Jost, Tanja, Raneri, Matteo, Guglielmetti, Simone, Gargari, Giorgio, Palatella, Martina, Willers, Maike, Fehlhaber, Beate, Werlein, Christopher, Vogl, Thomas, Roth, Johannes, Grassi, Fabio, Viemann, Dorothee

“…Malnutrition is linked to 45% of global childhood mortality, however, the impact of maternal malnutrition on the child’s health remains elusive. Previous…”
Get full text

A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI) by Hartmann, Carina R, Khan, Robin, Schöning, Jennifer, Richter, Maximilian, Willers, Maike, Pirr, Sabine, Heckmann, Julia, Dirks, Johannes, Morbach, Henner, Konrad, Monika, Fries, Elena, Winkler, Magdalene, Büchel, Johanna, Seidenspinner, Silvia, Fischer, Jonas, Vollmuth, Claudia, Meinhardt, Martin, Marissen, Janina, Schmolke, Mirco, Haid, Sibylle, Pietschmann, Thomas, Backes, Simone, Dölken, Lars, Löber, Ulrike, Keil, Thomas, Heuschmann, Peter U, Wöckel, Achim, Sagar, Ulas, Thomas, Forslund-Startceva, Sofia K, Härtel, Christoph, Viemann, Dorothee

“…Respiratory viral infections (RVIs) are a major global contributor to morbidity and mortality. The susceptibility and outcome of RVIs are strongly…”
Get full text

Silent neonatal influenza A virus infection primes systemic antimicrobial immunity by Heinemann, Anna Sophie, Stalp, Jan Lennart, Bonifacio, João Pedro Pereira, Silva, Filo, Willers, Maike, Heckmann, Julia, Fehlhaber, Beate, Völlger, Lena, Raafat, Dina, Normann, Nicole, Klos, Andreas, Hansen, Gesine, Schmolke, Mirco, Viemann, Dorothee

“…Infections with influenza A viruses (IAV) cause seasonal epidemics and global pandemics. The majority of these infections remain asymptomatic, especially among…”
Get full text

A sensitive scoring system for the longitudinal clinical evaluation and prediction of lethal disease outcomes in newborn mice by Fehlhaber, Beate, Heinemann, Anna S., Rübensam, Kathrin, Willers, Maike, Völlger, Lena, Pfeifer, Sandra, von Köckritz-Blickwede, Maren, Viemann, Dorothee

“…Neonatal animal models are increasingly employed in order to unravel age-specific disease mechanisms. Appropriate tools objectifying the clinical condition of…”
Get full text

Visual record of intertidal disturbance caused by drift ice in the spring on the Atlantic coast of Nova Scotia by Petzold, Willy, Willers, Maike T, Scrosati, Ricardo A

“…In the early spring of 2014, an unusually large amount of sea ice drifted from the Gulf of St. Lawrence, where it had been produced, towards the open Atlantic…”
Get full text

Role of the gut microbiota in airway immunity and host defense against respiratory infections by Willers, Maike, Viemann, Dorothee

“…Colonization of the intestine with commensal bacteria is known to play a major role in the maintenance of human health. An altered gut microbiome is associated…”
Get more information

Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth by Ravens, Sarina, Fichtner, Alina S., Willers, Maike, Torkornoo, Dennis, Pirr, Sabine, Schöning, Jennifer, Deseke, Malte, Sandrock, Inga, Bubke, Anja, Wilharm, Anneke, Dodoo, Daniel, Egyir, Beverly, Flanagan, Katie L., Steinbrück, Lars, Dickinson, Paul, Ghazal, Peter, Adu, Bright, Viemann, Dorothee, Prinz, Immo

“…Starting at birth, the immune system of newborns and children encounters and is influenced by environmental challenges. It is still not completely understood…”
Get full text

γδ T cell profiling in a cohort of preterm infants reveals elevated frequencies of CD83+ γδ T cells in sepsis by León-Lara, Ximena, Fichtner, Alina S, Willers, Maike, Yang, Tao, Schaper, Katharina, Riemann, Lennart, Schöning, Jennifer, Harms, Anna, Almeida, Vicente, Schimrock, Anja, Janssen, Anika, Ospina-Quintero, Laura, von Kaisenberg, Constantin, Förster, Reinhold, Eberl, Matthias, Richter, Manuela F, Pirr, Sabine, Viemann, Dorothee, Ravens, Sarina

“…Preterm infants are at high risk of developing neonatal sepsis. γδ T cells are thought to be an important set of effector cells in neonates. Here, γδ T cells…”
Get more information

Constitutive TNF‐α signaling in neonates is essential for the development of tissue‐resident leukocyte profiles at barrier sites by Bickes, Marie Sophie, Pirr, Sabine, Heinemann, Anna Sophie, Fehlhaber, Beate, Halle, Stephan, Völlger, Lena, Willers, Maike, Richter, Manuela, Böhne, Carolin, Albrecht, Melanie, Langer, Melissa, Pfeifer, Sandra, Jonigk, Danny, Vieten, Gertrud, Ure, Benno, Kaisenberg, Constantin, Förster, Reinhold, Köckritz-Blickwede, Maren, Hansen, Gesine, Viemann, Dorothee

“…ABSTRACT Newborn infants have a high disposition to develop systemic inflammatory response syndromes (SIRSs) upon inflammatory or infectious challenges…”
Get full text

Longitudinal development of the airway metagenome of preterm very low birth weight infants during the first two years of life by Rosenboom, Ilona, Pust, Marie-Madlen, Pirr, Sabine, Bakker, Alina, Willers, Maike, Davenport, Colin F, Wiehlmann, Lutz, Viemann, Dorothee, Tümmler, Burkhard

“…Preterm birth is accompanied with many complications and requires severe therapeutic regimens at the neonatal intensive care unit. The influence of the…”
Get full text

A mutation within the SH2 domain of slp‐76 regulates the tissue distribution and cytokine production of iNKT cells in mice by Danzer, Claudia, Koller, Anna, Baier, Julia, Arnold, Harald, Giessler, Claudia, Opoka, Robert, Schmidt, Stephanie, Willers, Maike, Mihai, Sidonia, Parsch, Hans, Wirtz, Stefan, Daniel, Christoph, Reinhold, Annegret, Engelmann, Swen, Kliche, Stefanie, Bogdan, Christian, Hoebe, Kasper, Mattner, Jochen

“…TCR ligation is critical for the selection, activation, and integrin expression of T lymphocytes. Here, we explored the role of the TCR adaptor protein slp‐76…”
Get full text