Search Results - "Willers, Jörg"

A vaccine against nicotine for smoking cessation: a randomized controlled trial by Cornuz, Jacques, Zwahlen, Susanne, Jungi, Walter Felix, Osterwalder, Joseph, Klingler, Karl, van Melle, Guy, Bangala, Yolande, Guessous, Idris, Müller, Philipp, Willers, Jörg, Maurer, Patrik, Bachmann, Martin F, Cerny, Thomas

“…Tobacco dependence is the leading cause of preventable death and disabilities worldwide and nicotine is the main substance responsible for the addiction to…”
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Proteomic Scan for Tyrosinase Peptide Antigenic Pattern in Vitiligo and Melanoma: Role of Sequence Similarity and HLA-DR1 Affinity by Lucchese, Alberta, Willers, Jorg, Mittelman, Abraham, Kanduc, Darja, Dummer, Reinhard

“…Immune responses contribute to the pathogenesis of vitiligo and target melanoma sometimes associated with vitiligo-like depigmentation in some melanoma…”
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Expression of melanoma-associated antigens in melanoma cell cultures by Urosevic, Mirjana, Braun, Bettina, Willers, Jörg, Burg, Günter, Dummer, Reinhard

“…:  The efficiency of melanoma immunotherapy appears to depend on both melanoma‐ and immune system‐specific factors. Melanoma‐specific factors include…”
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Molecular mimicry of phage displayed peptides mimicking GD3 ganglioside by Willers, Jörg, Lucchese, Alberta, Kanduc, Darja, Ferrone, Soldano

“…We have analyzed sequence homologies between nonimmunogenic phage displayed peptides mimicking GD3 ganglioside and human/mouse self-proteins. The GD3…”
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Interferon resistance of cutaneous T-cell lymphoma–derived clonal T-helper 2 cells allows selective viral replication by Dummer, Reinhard, Döbbeling, Udo, Geertsen, Ralf, Willers, Jörg, Burg, Günter, Pavlovic, Jovan

“…Cutaneous T-cell lymphomas (CTCL) comprise a heterogeneous group of lymphoproliferative disorders that are characterized by an accumulation of T-lymphocytes in…”
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Proliferation of CD30+ T-Helper 2 Lymphoma Cells Can Be Inhibited by CD30 Receptor Cross-Linking with Recombinant CD30 Ligand by WILLERS, Jörg, DUMMER, Reinhard, KEMPF, Werner, KÜNDIG, Thomas, BURG, Günter, KADIN, Marshall E

“…Purpose: Cutaneous anaplastic large cell lymphomas (ALCLs) are characterized by the expression of CD30, spontaneous regression of skin lesions, and increased…”
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Decreased Intraindividual HLA Class I Expression is due to Reduced Transcription in Advanced Melanoma and Does Not Correlate with HLA-G Expression by Willers, Jörg, Urosevic, Mirjana, Laine, Elisabeth, Kündig, Thomas, Burg, Günter, Dummer, Reinhard, Geertsen, Ralf

“…The presentation of endogenously synthesized peptides in association with HLA class I molecules allows the activation of CD8+ lymphocytes. Tumor cells often…”
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A therapeutic vaccine for nicotine dependence: preclinical efficacy, and phase I safety and immunogenicity by Maurer, Patrik, Jennings, Gary T., Willers, Jörg, Rohner, Franziska, Lindman, Ylva, Roubicek, Kirsten, Renner, Wolfgang A., Müller, Philipp, Bachmann, Martin F.

“…Nicotine is the principal addictive component in tobacco, and following uptake acts in the central nervous system. The smoking‐cessation efforts of most…”
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Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients by SPEISER, Daniel E, SCHWARZ, Katrin, VOELTER, Verena, CEROTTINI, Jean-Philippe, GUGGISBERG, David, WILLERS, Jörg, GELDHOF, Christine, ROMERO, Pedro, KÜNDIG, Thomas, KNUTH, Alexander, DUMMER, Reinhard, TREFZER, Uwe, BAUMGAERTNER, Petra, BACHMANN, Martin F, MANOLOVA, Vania, DEVEVRE, Estelle, STERRY, Wolfram, WALDEN, Peter, ZIPPELIUS, Alfred, BAUMANN CONZETT, Katrin, SENTI, Gabriela

“…Induction of cytotoxic CD8 T-cell responses is enhanced by the exclusive presentation of antigen through dendritic cells, and by innate stimuli, such as…”
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Non‐self‐discrimination as a driving concept in the identification of an immunodominant HMW‐MAA epitopic peptide sequence by autoantibodies from melanoma cancer patients by Dummer, Reinhard, Mittelman, Abraham, Fanizzi, Francesco P., Lucchese, Guglielmo, Willers, Jörg, Kanduc, Darja

“…We analyzed the sera of patients with melanoma to define the human humoral autoantibody profile towards HMW‐MAA. Computational proteome scanning using the…”
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Definition of anti-tyrosinase MAb T311 linear determinant by proteome-based similarity analysis by Willers, Jörg, Lucchese, Alberta, Mittelman, Abraham, Dummer, Reinhard, Kanduc, Darja

“…:  Using non‐self discrimination as a driving force in generating peptide immunogenicity, we have developed a computer‐assisted proteomic analysis in order to…”
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Identification of Monoclonal Anti-HMW-MAA Antibody Linear Peptide Epitope by Proteomic Database Mining by Mittelman, Abraham, Tiwari, Raj, Lucchese, Guglielmo, Willers, Jörg, Dummer, Reinhard, Kanduc, Darja

“…An efficient strategy is presented for the identification of antigenic sequences in the context of given MHC molecules of interest. The proteomic analysis of…”
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Bcl-2 and bcl-xL Antisense Oligonucleotides Induce Apoptosis in Melanoma Cells of Different Clinical Stages by Olie, Robert A., Hafner, Christoph, Küttel, Renzo, Sigrist, Brigitte, Stahel, Rolf A., Zangemeister-Wittke, Uwe, Willers, Jörg, Dummer, Reinhard, Hall, Jonathan

“…Recent clinical studies have shown the promise of bcl-2 antisense therapy in patients with melanoma. To further demonstrate the importance of bcl-2 and…”
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The use of anti‐T‐cell receptor‐Vβ antibodies for the estimation of treatment success and phenotypic characterization of clonal T‐cell populations in cutaneous T‐cell lymphomas by Schwab, Cornelia, Willers, Jörg, Niederer, Eva, Ludwig, Elisabeth, Kündig, Thomas, Grob, Peter, Burg, Günter, Dummer, Reinhard

“…Sézary syndrome and Mycosis fungoides are the most common forms of cutaneous T‐cell lymphomas. To assess the response to different therapies especially in…”
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Expression of Melan-A/MART-1 in primary melanoma cell cultures has prognostic implication in metastatic melanoma patients by Murer, Karin, Urosevic, Mirjana, Willers, Jörg, Selvam, Philomina, Laine, Elisabeth, Burg, Günter, Dummer, Reinhard

“…The lack of melanoma-associated antigen (MAA) expression has been associated with the reduced overall survival in melanoma patients. In order to investigate…”
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The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas by Schwab, Cornelia, Willers, Jörg, Niederer, Eva, Ludwig, Elisabeth, Kündig, Thomas, Grob, Peter, Burg, Günter, Dummer, Reinhard

“…Sézary syndrome and Mycosis fungoides are the most common forms of cutaneous T-cell lymphomas. To assess the response to different therapies especially in…”
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Loss of single HLA Class I allospecificities in melanoma cells due to selective genomic abbreviations by Geertsen, Ralf, Böni, Roland, Blasczyk, Rainer, Romero, Pedro, Betts, David, Rimoldi, Donata, Hong, Xin, Laine, Elisabeth, Willers, Jörg, Dummer, Reinhard

“…Expression of human leucocyte antigen (HLA) Class I molecules is essential for the recognition of malignant melanoma (MM) cells by CD8+ T lymphocytes. A…”
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The Interferon Inhibiting Cytokine IK is Overexpressed in Cutaneous T Cell Lymphoma Derived Tumor Cells That Fail to Upregulate Major Histocompatibility Complex Class II Upon Interferon-γ Stimulation by Willers, Jörg, Häffner, Andreas, Zepter, Karoline, Storz, Monique, Urosevic, Mirjana, Burg, Günter, Dummer, Reinhard

“…Cutaneous T cell lymphomas are characterized by an accumulation of malignant clonal lymphocytes in the skin and occasionally in the blood. We compared gene…”
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The Interferon Inhibiting Cytokine IK is Overexpressed in Cutaneous T Cell Lymphoma Derived Tumor Cells That Fail to Upregulate Major Histocompatibility Complex Class II Upon Interferon- Stimulation by Willers, Jörg, Häffner, Andreas, Zepter, Karoline, Storz, Monique, Urosevic, Mirjana, Burg, Günter, Dummer, Reinhard

“…Cutaneous T cell lymphomas are characterized by an accumulation of malignant clonal lymphocytes in the skin and occasionally in the blood. We compared gene…”
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Apparent trans-chromosomal antibody class switch in mice bearing an igha μ-chain transgene on an ighb genetic background by Willers, Jörg, Kolb, Cornelia, Weiler, Eberhardt

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