Search Results - "Willers, Clarissa"

Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors by Gouws, Chrisna, Smit, Tanya, Willers, Clarissa, Svitina, Hanna, Calitz, Carlemi, Wrzesinski, Krzysztof

“…Colorectal cancer remains to be one of the leading causes of death worldwide, with millions of patients diagnosed each year. Although chemotherapeutic drugs…”
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Investigation and Evaluation of the Transdermal Delivery of Ibuprofen in Various Characterized Nano-Drug Delivery Systems by Myburgh, Jeanri, Liebenberg, Wilna, Willers, Clarissa, Dube, Admire, Gerber, Minja

“…The aim was to assess the suitability of three nano-based transdermal drug delivery systems containing ibuprofen: a nano-emulsion, a nano-emulgel, and a…”
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Wound Healing Effects of Aloe muth-muth: In Vitro Investigations Using Immortalized Human Keratinocytes (HaCaT) by Fouche, Morne, Willers, Clarissa, Hamman, Sias, Malherbe, Christiaan, Steenekamp, Jan

“…The traditional use of Aloe spp. for the purpose of wound healing has a long history and is widespread internationally. Recently, a hybrid aloe plant (Aloe…”
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Intestinal Drug Absorption Enhancement by Aloe vera Gel and Whole Leaf Extract: In Vitro Investigations into the Mechanisms of Action by Haasbroek, Anja, Willers, Clarissa, Glyn, Matthew, du Plessis, Lissinda, Hamman, Josias

“…The co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the…”
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A novel NCI‐H69V small cell lung cancer functional mini‐tumor model for future treatment screening applications by Merwe, Liezaan, Svitina, Hanna, Willers, Clarissa, Wrzesinski, Krzysztof, Gouws, Chrisna

“…Small cell lung cancer (SCLC) is aggressive and despite multiple clinical trials, its standard of care is unchanged for the past three decades. In vitro cancer…”
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In vitro wound healing effects of combinations of Aloe vera gel with different extracts of Bulbine frutescens by Hattingh, Anri, Laux, Jean-Pierre, Willers, Clarissa, Hamman, Josias, Steyn, Dewald, Hamman, Hannlie

“…•vera gel, B. frutescens aqueous and gel extracts showed wound healing effects.•Combining A. vera gel and B. frutescens aqueous extract increased wound…”
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Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors by Willers, Clarissa, Wentzel, Johannes Frederik, du Plessis, Lissinda Hester, Gouws, Chrisna, Hamman, Josias Hendrik

“…Microbial resistance against antibiotics is a serious threat to the effective treatment of infectious diseases. Several mechanisms exist through which…”
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Can a metabolomics-based approach be used as alternative to analyse fatty acid methyl esters from soil microbial communities? by Willers, Clarissa, Jansen van Rensburg, Peet J., Claassens, Sarina

“…Modern high-throughput approaches such as metabolomics, holds promise for investigating microbial communities. This study evaluated the quantitative and…”
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Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening by Smit, Tanya, Calitz, Carlemi, Willers, Clarissa, Svitina, Hanna, Hamman, Josias, Fey, Stephen J, Gouws, Chrisna, Wrzesinski, Krzysztof

“…Colorectal cancer is one of the leading causes of cancer-related deaths. A main problem for its treatment is resistance to chemotherapy, requiring the…”
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Potential Herb-Drug Pharmacokinetic Interactions between African Wild Olive Leaf Extract and Selected Antihypertensive Drugs by Mmopele, Katlego, Combrinck, Sandra, Hamman, Josias, Willers, Clarissa, Chen, Weiyang, Viljoen, Alvaro

“…The African wild olive ( subsp. ) is traditionally used as a hypotensive agent. Herb-drug interactions may result from the concurrent use of herbal medicines…”
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In Vitro Anti-melanoma Efficacy and Selectivity of Withania somnifera by Chinembiri, Tawona N., du Plessis, Lissinda H., Willers, Clarissa, Davids, Lester M., Gerber, Minja, du Plessis, Jeanetta

“…Withania somnifera (L.) Dunal, Solanaceae, is a shrub known to have anti-cancer, anti-hypertensive, anti-inflammatory, and immunostimulatory properties. The…”
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Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension by Louw, Estelle-Vionè, Liebenberg, Wilna, Willers, Clarissa, Dube, Admire, Aucamp, Marique E., Gerber, Minja

“…Transdermal delivery of active pharmaceutical ingredients (APIs) can be challenging, since the skin possesses a rate-limiting barrier, which may be overcome…”
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Models used to screen for the treatment of multidrug resistant cancer facilitated by transporter-based efflux by Willers, Clarissa, Svitina, Hanna, Rossouw, Michael J., Swanepoel, Roan A., Hamman, Josias H., Gouws, Chrisna

“…Purpose Efflux transporters of the adenosine triphosphate-binding cassette (ABC)-superfamily play an important role in the development of multidrug resistance…”
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