Search Results - "Willerford, Dennis M."

Analysis of ku80-Mutant Mice and Cells with Deficient Levels of p53 by Lim, Dae-Sik, Vogel, Hannes, Willerford, Dennis M., Sands, Arthur T., Platt, Kenneth A., Hasty, Paul

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene by Bories, Jean-Christophe, Willerford, Dennis M, Grévin, Delphine, Davidson, Laurie, Camus, Anne, Martin, Patrick, Stéhelin, Dominique, Alt, Frederick W

“…The Ets-1 proto-oncogene is a member of a transcription factor family characterized by homology to the v-ets oncogene. In adult mice, Ets-1 is expressed…”
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Regulation of T-cell receptor Dβ1 promoter by KLF5 through reiterated GC-rich motifs by Yang, Xuexian O., Doty, Raymond T., Hicks, Justin S., Willerford, Dennis M.

“…Rearrangement of T-cell receptor (TCR) and immunoglobulin genes by a common V(D)J recombination machinery is regulated by developmentally specific chromatin…”
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T Cell Growth Cytokines Cause the Superinduction of Molecules Mediating Antigen-Induced T Lymphocyte Death by Zheng, Lixin, Trageser, Carol L, Willerford, Dennis M, Lenardo, Michael J

“…TCR stimulation of T lymphocytes that are activated and cycling in the presence of IL-2 leads to programmed cell death. We now show that this effect is at…”
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Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase by Vanasse, G J, Halbrook, J, Thomas, S, Burgess, A, Hoekstra, M F, Disteche, C M, Willerford, D M

“…Chromosome translocations involving antigen receptor loci are a genetic hallmark of non-Hodgkin's lymphomas in humans. Most commonly, these translocations…”
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Mutations and molecular variants of the NBS1 gene in non-Hodgkin lymphoma by Cerosaletti, Karen M., Morrison, V. Anne, Sabath, Daniel E., Willerford, Dennis M., Concannon, Patrick

“…Non‐Hodgkin lymphomas (NHLs) are characterized by chromosomal translocations that juxtapose loci encoding lymphoid antigen receptors with cellular…”
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Regulation of Lymphoid Homeostasis by IL-2 Receptor Signals In Vivo by Leung, Danny T. M, Morefield, Samantha, Willerford, Dennis M

“…High-affinity IL-2R signals are required for peripheral lymphoid homeostasis in vivo. We found that CD25 was required for regulation of peripheral T cells in…”
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Detection of HIV DNA in Cervical and Vaginal Secretions: Prevalence and Correlates Among Women in Nairobi, Kenya by Clemetson, David B. A, Moss, Gregory B, Willerford, Dennis M, Hensel, Michelle, Emonyi, Wilfred, Holmes, King K, Plummer, Francis, Ndinya-Achola, Jackoniah, Roberts, Pacita L, Hillier, Sharon, Kreiss, Joan K

“…Objective.—Factors that influence heterosexual transmission of the human immunodeficiency virus (HIV), including sexually transmitted diseases, contraceptive…”
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JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells by Zhao, Shengming, Zoller, Karen, Masuko, Masayoshi, Rojnuckarin, Ponlapat, Yang, Xuexian O., Parganas, Evan, Kaushansky, Kenneth, Ihle, James N., Papayannopoulou, Thalia, Willerford, Dennis M., Clackson, Tim, Blau, C.Anthony

“…Defining signals that can support the self‐renewal of multipotential hemopoietic progenitor cells (MHPCs) is pertinent to understanding leukemogenesis and may…”
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Developmental regulation of V(D)J recombination and lymphocyte differentiation by Willerford, Dennis M, Swat, Wojciech, Alt, Frederick W

“…Recent insights into the mechanism of V(D)J recombination have clarified the direct role of the products of the recombination-activating genes Rag-1 and Rag-2…”
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Perturbation of B-cell development in mice overexpressing the Bcl-2 homolog A1 by Chuang, Peter I., Morefield, Samantha, Liu, Chien-Ying, Chen, Stephen, Harlan, John M., Willerford, Dennis M.

“…Decisions about cell survival or death are central components of adaptive immunity and occur at several levels in immune system development and function. The…”
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V(D)J rearrangement in Nijmegen breakage syndrome by Yeo, Tiong Chia, Xia, Dong, Hassouneh, Samar, Yang, Xuexian O, Sabath, Daniel E, Sperling, Karl, Gatti, Richard A, Concannon, Patrick, Willerford, Dennis M

“…Repair of DNA double-strand breaks is essential for maintenance of genomic stability, and is specifically required for rearrangement of immunoglobulin (Ig) and…”
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The Leukemia-Associated Gene Mllt1/ENL: Characterization of a Murine Homolog and Demonstration of an Essential Role in Embryonic Development by Doty, Raymond T., Vanasse, Gary J., Disteche, Christine M., Willerford, Dennis M.

“…ABSTRACT MLLT1 (ENL/LTG19) is one of a number of fusion gene partners with the MLL oncogene involved in 11q23 translocations in human leukemia and encodes a…”
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Biology of the interleukin-2 receptor by Nelson, B H, Willerford, D M

“…Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current…”
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Chimeric del20q in a case of chronic neutrophilic leukemia by FRANK, M. B, NORWOOD, T. H, WILLERFORD, D. M

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Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment by Willerford, D M, Chen, J, Ferry, J A, Davidson, L, Ma, A, Alt, F W

“…Interleukin-2 receptor alpha chain (IL-2R alpha) expression occurs at specific stages of early T and B lymphocyte development and is induced upon activation of…”
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Regulated Genomic Instability and Neoplasia in the Lymphoid Lineage by Vanasse, Gary J., Concannon, Patrick, Willerford, Dennis M.

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Regulation of T-cell receptor D beta 1 promoter by KLF5 through reiterated GC-rich motifs by Yang, Xuexian O, Doty, Raymond T, Hicks, Justin S, Willerford, Dennis M

“…Rearrangement of T-cell receptor (TCR) and immunoglobulin genes by a common V(D)J recombination machinery is regulated by developmentally specific chromatin…”
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Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor by Van Parijs, L, Biuckians, A, Ibragimov, A, Alt, FW, Willerford, DM, Abbas, AK

“…IL-2 was initially defined as a T lymphocyte growth factor, but recent studies have provided evidence that it may also play a role in regulating T cell…”
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Promoter Element for Transcription of Unrearranged T-Cell Receptor β-Chain Gene in Pro-T Cells by Doty, Raymond T., Xia, Dong, Nguyen, Suzanne P., Hathaway, Tanya R., Willerford, Dennis M.

“…The hallmark of T- and B-lymphocyte development is the rearrangement of variable (V), diversity (D), and joining (J) segments of T-cell receptor (TCR) and…”
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