Search Results - "Willems, Andreas"

Artemisinin-Based Drugs Target the Plasmodium falciparum Heme Detoxification Pathway by Ribbiso, Kaleab A, Heller, Laura E, Taye, Abigail, Julian, Erin, Willems, Andreas V, Roepe, Paul D

“…Artemisinin (ART)-based antimalarial drugs are believed to exert lethal effects on malarial parasites by alkylating a variety of intracellular molecular…”
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β-Strand inspired bifacial π-conjugated polymers by Chaudhuri, Saikat, Mohanan, Manikandan, Willems, Andreas V, Bertke, Jeffery A, Gavvalapalli, Nagarjuna

“…Access to diverse, relatively high molecular weight soluble linear polymers without pendant solubilizing chains is the key to solution state synthesis of…”
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A practical diastereoselective synthesis of (−)‐bestatin by Shang, Suisheng, Willems, Andreas V., Chauhan, Satendra S.

“…Diastereoselective addition of nitromethane to Boc‐D‐Phe‐H in the presence of sodium hydride in diethyl ether/hexane containing 15‐crown‐5 and subsequent…”
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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology by Hagenah, Laura M, Dhingra, Satish K, Small-Saunders, Jennifer L, Qahash, Tarrick, Willems, Andreas, Schindler, Kyra A, Rangel, Gabriel W, Gil-Iturbe, Eva, Kim, Jonathan, Akhundova, Emiliya, Yeo, Tomas, Okombo, John, Mancia, Filippo, Quick, Matthias, Roepe, Paul D, Llinás, Manuel, Fidock, David A

“…Our study leverages gene editing techniques in asexual blood stage parasites to profile novel mutations in mutant PfCRT, an important mediator of piperaquine…”
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Das ABC des Nagoya-Protokolls in Deutschland – Zugang zu genetischen Ressourcen und Vorteilsausgleich by Kai Metge, Lothar Frese, Andreas Willems

“…Seit dem 12.10.2014 ist für die Mitgliedstaaten der Europäischen Union die „Verordnung (EU) Nr. 511/2014 des Europäischen Parlaments und des Rates vom 16…”
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Structures of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) Isoforms and Their Interactions with Chloroquine by Willems, Andreas, Kalaw, Adrian, Ecer, Ayse, Kotwal, Amitesh, Roepe, Luke D., Roepe, Paul D.

“…Using a recently elucidated atomic-resolution cryogenic electron microscopy (cryo-EM) structure for the Plasmodium falciparum chloroquine resistance…”
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The Role of the Digestive Vacuole Redox Homeostasis on Drug Resistance in Plasmodium falciparum by Willems, Andreas Vedsø

“…The recent emergence of artemisinin (ART) resistance in Plasmodium falciparum malarial parasites is of major concern and has focused attention on the mechanism…”
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β-Strand inspired bifacial π-conjugated polymers† †Electronic supplementary information (ESI) available: Synthesis and characterization of small molecules and polymers. CCDC 1885228–1885230. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc01724k by Chaudhuri, Saikat, Mohanan, Manikandan, Willems, Andreas V., Bertke, Jeffery A., Gavvalapalli, Nagarjuna

“…β-Strand inspired bifacial π-conjugated polymers that are soluble despite the absence of pendant solubilizing chains are reported. Precise tunability of the…”
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Towards the Use of Gamification Frameworks in Learning Environments by Rauschenberger, Maria, Willems, Andreas, Ternieden, Menno, Thomaschewski, Jörg

“…Gamification is an established concept to apply game elements in different contexts to engage and motivate users. Gamification has been successfully used in…”
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Modified primers for rapid and direct electrochemical analysis of coeliac disease associated HLA alleles by Joda, Hamdi, Beni, Valerio, Willems, Andreas, Frank, Rainer, Höth, Julian, Lind, Kristina, Strömbom, Linda, Katakis, Ioanis, O´Sullivan, Ciara K.

“…Direct detection of PCR product via hybridisation assay, would facilitate the development of rapid tools for genetic analysis. Here, a PCR primer designed to…”
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