Search Results - "Willem, J.M."

A Genotype-Guided Strategy for Oral P2Y12 Inhibitors in Primary PCI by Claassens, Daniel M.F, Vos, Gerrit J.A, Bergmeijer, Thomas O, Hermanides, Renicus S, van ’t Hof, Arnoud W.J, van der Harst, Pim, Barbato, Emanuele, Morisco, Carmine, Tjon Joe Gin, Richard M, Asselbergs, Folkert W, Mosterd, Arend, Herrman, Jean-Paul R, Dewilde, Willem J.M, Janssen, Paul W.A, Kelder, Johannes C, Postma, Maarten J, de Boer, Anthonius, Boersma, Cornelis, Deneer, Vera H.M, ten Berg, Jurriën M

“…Patients undergoing primary PCI were randomly assigned to either a genotype-guided strategy for selecting a P2Y 12 inhibitor or to standard treatment with…”
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Perspectives and opportunities for nanomedicine in the management of atherosclerosis by Mulder, Willem J. M, Lobatto, Mark E, Fuster, Valentin, Fayad, Zahi A

“…Key Points Nanomedicine — the use of nanotechnology for medical purposes — is a fast-growing field that has had numerous applications in cancer and is now…”
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Same, different, or closely related: What is the relationship between language production and comprehension? by Meyer, Antje S., Huettig, Falk, Levelt, Willem J.M.

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Atherosclerotic Plaque Targeting Mechanism of Long-Circulating Nanoparticles Established by Multimodal Imaging by Lobatto, Mark E, Calcagno, Claudia, Millon, Antoine, Senders, Max L, Fay, Francois, Robson, Philip M, Ramachandran, Sarayu, Binderup, Tina, Paridaans, Maarten P.M, Sensarn, Steven, Rogalla, Stephan, Gordon, Ronald E, Cardoso, Luis, Storm, Gert, Metselaar, Josbert M, Contag, Christopher H, Stroes, Erik S. G, Fayad, Zahi A, Mulder, Willem J.M

“…Atherosclerosis is a major cause of global morbidity and mortality that could benefit from novel targeted therapeutics. Recent studies have shown efficient and…”
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Nanotechnology in Medical Imaging: Probe Design and Applications by Cormode, David P, Skajaa, Torjus, Fayad, Zahi A, Mulder, Willem J.M

“…Nanoparticles have become more and more prevalent in reports of novel contrast agents, especially for molecular imaging, the detection of cellular processes…”
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The Effect of Nanoparticle Polyethylene Glycol Surface Density on Ligand-Directed Tumor Targeting Studied in Vivo by Dual Modality Imaging by Hak, Sjoerd, Helgesen, Emily, Hektoen, Helga H, Huuse, Else Marie, Jarzyna, Peter A, Mulder, Willem J.M, Haraldseth, Olav, Davies, Catharina de Lange

“…The development and application of nanoparticles as in vivo delivery vehicles for therapeutic and/or diagnostic agents has seen a drastic growth over the last…”
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Nonpharmacological Lipoprotein Apheresis Reduces Arterial Inflammation in Familial Hypercholesterolemia by van Wijk, Diederik F., MD, Sjouke, Barbara, MD, Figueroa, Amparo, MD, Emami, Hamed, MD, van der Valk, Fleur M., MD, MacNabb, Megan H., BA, Hemphill, Linda C., MD, Schulte, Dominik M., MD, PhD, Koopman, Marion G., MD, PhD, Lobatto, Mark E., MD, Verberne, Hein J., MD, PhD, Fayad, Zahi A., MD, PhD, Kastelein, John J.P., MD, PhD, Mulder, Willem J.M., PhD, Hovingh, G. Kees, MD, PhD, Tawakol, Ahmed, MD, Stroes, Erik S.G., MD, PhD

“…Abstract Background Patients with familial hypercholesterolemia (FH) are characterized by elevated atherogenic lipoprotein particles, predominantly low-density…”
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Whole-Body Atherosclerosis Imaging by Positron Emission Tomography/Magnetic Resonance Imaging: From Mice to Nonhuman Primates by Calcagno, Claudia, Pérez-Medina, Carlos, Mulder, Willem J.M., Fayad, Zahi A.

“…Cardiovascular disease due to atherosclerosis is still the main cause of morbidity and mortality worldwide. This disease is a complex systemic disorder arising…”
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A systematic comparison of clinically viable nanomedicines targeting HMG-CoA reductase in inflammatory atherosclerosis by Alaarg, Amr, Senders, Max L., Varela-Moreira, Aida, Pérez-Medina, Carlos, Zhao, Yiming, Tang, Jun, Fay, Francois, Reiner, Thomas, Fayad, Zahi A., Hennink, Wim E., Metselaar, Josbert M., Mulder, Willem J.M., Storm, Gert

“…Atherosclerosis is a leading cause of worldwide morbidity and mortality whose management could benefit from novel targeted therapeutics. Nanoparticles are…”
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Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration by van der Valk, Fleur M., M.D, van Wijk, Diederik F, Lobatto, Mark E, Verberne, Hein J, Storm, Gert, Willems, Martine C.M, Legemate, Dink A, Nederveen, Aart J, Calcagno, Claudia, Mani, Venkatesh, Ramachandran, Sarayu, Paridaans, Maarten P.M, Otten, Maarten J, Dallinga-Thie, Geesje M, Fayad, Zahi A, Nieuwdorp, Max, Schulte, Dominik M, Metselaar, Josbert M, Mulder, Willem J.M, Stroes, Erik S., M.D., Ph.D

“…Abstract Drug delivery to atherosclerotic plaques via liposomal nanoparticles may improve therapeutic agents’ risk–benefit ratios. Our paper details the first…”
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Efficacy and Safety of the Use of Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation and Concomitant Aspirin Therapy: A Meta-Analysis of Randomized Trials by Bennaghmouch, Naoual, de Veer, Anne J.W.M, Bode, Kerstin, Mahmoodi, Bakhtawar K, Dewilde, Willem J.M, Lip, Gregory Y.H, Brueckmann, Martina, Kleine, Eva, ten Berg, Jurriën M

“…BACKGROUND:Current guidelines recommend non–vitamin K antagonist oral anticoagulants (NOACs) as the first-choice therapy in patients with nonvalvular atrial…”
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RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions by Hogstad, Brandon, Berres, Marie-Luise, Chakraborty, Rikhia, Tang, Jun, Bigenwald, Camille, Serasinghe, Madhavika, Lim, Karen Phaik Har, Lin, Howard, Man, Tsz-Kwong, Remark, Romain, Baxter, Samantha, Kana, Veronika, Jordan, Stefan, Karoulia, Zoi, Kwan, Wing-Hong, Leboeuf, Marylene, Brandt, Elisa, Salmon, Helene, McClain, Kenneth, Poulikakos, Poulikos, Chipuk, Jerry, Mulder, Willem J M, Allen, Carl E, Merad, Miriam

“…Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by granulomatous lesions containing pathological CD207 dendritic cells…”
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Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis by Ye, Yu-Xiang, Calcagno, Claudia, Binderup, Tina, Courties, Gabriel, Keliher, Edmund J, Wojtkiewicz, Gregory R, Iwamoto, Yoshiko, Tang, Jun, Pérez-Medina, Carlos, Mani, Venkatesh, Ishino, Seigo, Johnbeck, Camilla Bardram, Knigge, Ulrich, Fayad, Zahi A, Libby, Peter, Weissleder, Ralph, Tawakol, Ahmed, Dubey, Shipra, Belanger, Anthony P, Di Carli, Marcelo F, Swirski, Filip K, Kjaer, Andreas, Mulder, Willem J.M, Nahrendorf, Matthias

“…RATIONALE:Local plaque macrophage proliferation and monocyte production in hematopoietic organs promote progression of atherosclerosis. Therefore, noninvasive…”
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On Becoming a Physicist of Mind by Levelt, Willem J.M

“…In 1976, the German Max Planck Society established a new research enterprise in psycholinguistics, which became the Max Planck Institute for Psycholinguistics…”
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Imaging Systemic Inflammatory Networks in Ischemic Heart Disease by Nahrendorf, Matthias, MD, Frantz, Stefan, MD, Swirski, Filip K., PhD, Mulder, Willem J.M., PhD, Randolph, Gwendalyn, PhD, Ertl, Georg, MD, Ntziachristos, Vasilis, PhD, Piek, Jan J., MD, Stroes, Erik S., MD, Schwaiger, Markus, MD, Mann, Douglas L., MD, Fayad, Zahi A., PhD

“…Abstract While acute myocardial infarction mortality declines, patients continue to face reinfarction and/or heart failure. The immune system, which intimately…”
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Real‐Time Monitoring of Nanoparticle Formation by FRET Imaging by Sanchez‐Gaytan, Brenda L., Fay, François, Hak, Sjoerd, Alaarg, Amr, Fayad, Zahi A., Pérez‐Medina, Carlos, Mulder, Willem J. M., Zhao, Yiming

“…Understanding the formation process of nanoparticles is of the utmost importance to improve their design and production. This especially holds true for…”
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High-Density Lipoprotein–Based Contrast Agents for Multimodal Imaging of Atherosclerosis by Skajaa, Torjus, Cormode, David P, Falk, Erling, Mulder, Willem J.M, Fisher, Edward A, Fayad, Zahi A

“…Lipoproteins, natural nanoparticles, have a well-recognized biological role and are highly suitable as a platform for delivering imaging agents. The ease with…”
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The biological properties of iron oxide core high-density lipoprotein in experimental atherosclerosis by Skajaa, Torjus, Cormode, David P, Jarzyna, Peter A, Delshad, Amanda, Blachford, Courtney, Barazza, Alessandra, Fisher, Edward A, Gordon, Ronald E, Fayad, Zahi A, Mulder, Willem J.M

“…Abstract Lipoproteins are a family of plasma nanoparticles responsible for the transportation of lipids throughout the body. High-density lipoprotein (HDL),…”
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In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models by Pérez-Medina, Carlos, PhD, Binderup, Tina, PhD, Lobatto, Mark E., MD, PhD, Tang, Jun, PhD, Calcagno, Claudia, MD, PhD, Giesen, Luuk, BSc, Wessel, Chang Ho, MD, Witjes, Julia, MD, Ishino, Seigo, PhD, Baxter, Samantha, MHS, Zhao, Yiming, PhD, Ramachandran, Sarayu, PhD, Eldib, Mootaz, MSc, Sánchez-Gaytán, Brenda L., PhD, Robson, Philip M., PhD, Bini, Jason, PhD, Granada, Juan F., MD, Fish, Kenneth M., PhD, Stroes, Erik S.G., MD, PhD, Duivenvoorden, Raphaël, MD, PhD, Tsimikas, Sotirios, MD, Lewis, Jason S., PhD, Reiner, Thomas, PhD, Fuster, Valentín, MD, PhD, Kjær, Andreas, MD, PhD, Fisher, Edward A., MD, PhD, Fayad, Zahi A., PhD, Mulder, Willem J.M., PhD

“…Abstract Objectives The goal of this study was to develop and validate a noninvasive imaging tool to visualize the in vivo behavior of high-density lipoprotein…”
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Systems Biology and Noninvasive Imaging of Atherosclerosis by Calcagno, Claudia, Mulder, Willem J.M, Nahrendorf, Matthias, Fayad, Zahi A

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