Search Results - "Willekens, M"
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Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
Published in Nature communications (10-04-2023)“…Viral tropism within the brain and the role(s) of vertebrate immune response to neurotropic flaviviruses infection is largely understudied. We combine…”
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2
A Quantitative Evaluation of Joint Activity and Attenuation Reconstruction in TOF PET/MR Brain Imaging
Published in Journal of Nuclear Medicine (01-11-2019)“…Time-of-flight (TOF) PET data provide an effective means for attenuation correction (AC) when no (or incomplete or inaccurate) attenuation information is…”
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3
Editorial: Epidemiology, diagnosis, prognosis and treatment of rare immune-mediated diseases of the central nervous system
Published in Frontiers in neurology (13-12-2023)Get full text
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4
Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks
Published in European journal of nuclear medicine and molecular imaging (01-03-2017)“…During the past decades, extensive efforts have been made to expand the knowledge of amyotrophic lateral sclerosis (ALS). However, clinical translation of this…”
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5
Mesoscopic Optical Imaging of the Pancreas-Revisiting Pancreatic Anatomy and Pathophysiology
Published in Frontiers in endocrinology (Lausanne) (04-03-2021)“…The exocrine-endocrine multipart organization of the pancreas makes it an exceedingly challenging organ to analyze, quantitatively and spatially. Both in…”
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6
Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin
Published in Molecular imaging and biology (01-10-2016)“…Purpose Noninvasive beta cell mass (BCM) quantification is a crucial tool to understand diabetes development and progression. [ 111 In]exendin is a promising…”
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An MR-based brain template and atlas for optical projection tomography and light sheet fluorescence microscopy in neuroscience
Published in Frontiers in neuroscience (2024)“…Optical Projection Tomography (OPT) and light sheet fluorescence microscopy (LSFM) are high resolution optical imaging techniques, ideally suited for ex vivo…”
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8
Real‐time online monitoring of insect cell proliferation and baculovirus infection using digital differential holographic microscopy and machine learning
Published in Biotechnology progress (01-03-2023)“…Real‐time, detailed online information on cell cultures is essential for understanding modern biopharmaceutical production processes. The determination of key…”
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9
Non-invasive in vivo determination of viable islet graft volume by 111In-exendin-3
Published in Scientific reports (03-08-2017)“…Pancreatic islet transplantation is a promising therapy for patients with type 1 diabetes. However, the duration of long-term graft survival is limited due to…”
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10
SPECT of Transplanted Islets of Langerhans by Dopamine 2 Receptor Targeting in a Rat Model
Published in Molecular pharmaceutics (04-01-2016)“…Pancreatic islet transplantation can be a more permanent treatment for type 1 diabetes compared to daily insulin administration. Quantitative and longitudinal…”
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Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [ 123I]IBZM
Published in Diabetes, obesity & metabolism (01-04-2017)“…A non‐invasive imaging method to monitor islet grafts could provide novel and improved insight into the fate of transplanted islets and, potentially, monitor…”
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12
Quality of after-hours primary care in The Netherlands: adherence to national guidelines
Published in BMJ quality & safety (01-03-2011)“…To assess the quality of after-hours clinical care as delivered by general practitioner (GP) cooperatives in The Netherlands. A cross-sectional analysis was…”
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13
From Mice to Humans: The Exocrine Pancreas Does Not Matter in Human GLP-1 Receptor Imaging
Published in Journal of Nuclear Medicine (10-05-2021)Get full text
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14
Out-of-hours primary care: development of indicators for prescribing and referring
Published in International journal for quality in health care (01-10-2007)“…AbstractBackground Dutch general practitioners have reorganized their out-of-hours primary health care to general practice cooperatives. Good insight into the…”
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15
Characterization of 111In-labeled Glucose-Dependent Insulinotropic Polypeptide as a Radiotracer for Neuroendocrine Tumors
Published in Scientific reports (13-02-2018)“…Somatostatin receptor targeting is considered the standard nuclear medicine technique for visualization of neuroendocrine tumors (NET). Since not all NETs…”
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16
Is there a glucose metabolic signature of spreading TDP-43 pathology in amyotrophic lateral sclerosis?
Published in The quarterly journal of nuclear medicine and molecular imaging (01-03-2020)“…Recently, four neuropathological stages of amyotrophic lateral sclerosis (ALS) with spreading of transactive response DNA-binding protein-43 pathology were…”
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17
Non-invasive in vivo determination of viable islet graft volume by 111 In-exendin-3
Published in Scientific reports (03-08-2017)“…Pancreatic islet transplantation is a promising therapy for patients with type 1 diabetes. However, the duration of long-term graft survival is limited due to…”
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18
Regional Accuracy of ZTE-Based Attenuation Correction in Static [18F]FDG and Dynamic [18F]PE2I Brain PET/MR
Published in Frontiers in physics (06-12-2019)“…Accurate MR-based attenuation correction (MRAC) is essential for quantitative PET/MR imaging of the brain. In this study, we analyze the regional bias caused…”
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19
Spallation yields of neutrons produced in thick lead/bismuth targets by protons at incident energies of 420 and 590 MeV
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (2004)“…Spallation-neutron yields for protons at E p=420 and 590 MeV incident on thick Pb/Bi targets have been measured via activation analysis of Au and Mn foils at…”
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SCK·CEN contribution to the IAEA Round Robin exercise on WWER-440 RPV weld material: irradiation, annealing and re-embrittlement
Published in The International journal of pressure vessels and piping (01-08-2002)“…In the frame of an IAEA Round-Robin exercise, SCK·CEN has extensively characterized the mechanical properties of the WWER-440 weld material in the following…”
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