Search Results - "Willekens, A."

Type I interferon shapes brain distribution and tropism of tick-borne flavivirus by Chotiwan, Nunya, Rosendal, Ebba, Willekens, Stefanie M. A., Schexnaydre, Erin, Nilsson, Emma, Lindqvist, Richard, Hahn, Max, Mihai, Ionut Sebastian, Morini, Federico, Zhang, Jianguo, Ebel, Gregory D., Carlson, Lars-Anders, Henriksson, Johan, Ahlgren, Ulf, Marcellino, Daniel, Överby, Anna K.

“…Viral tropism within the brain and the role(s) of vertebrate immune response to neurotropic flaviviruses infection is largely understudied. We combine…”
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Erythrocyte vesiculation: a self‐protective mechanism? by Willekens, Frans L. A., Werre, Jan M., Groenen‐Döpp, Yvonne A. M., Roerdinkholder‐Stoelwinder, Bregt, De Pauw, Ben, Bosman, Giel J. C. G. M.

“…Summary Previous studies demonstrated that 20% of haemoglobin is lost from circulating erythrocytes during their total lifespan by vesiculation. To study…”
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Mesoscopic Optical Imaging of the Pancreas-Revisiting Pancreatic Anatomy and Pathophysiology by Alanentalo, Tomas, Hahn, Max, Willekens, Stefanie M A, Ahlgren, Ulf

“…The exocrine-endocrine multipart organization of the pancreas makes it an exceedingly challenging organ to analyze, quantitatively and spatially. Both in…”
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Use of defibrotide to treat transplant-associated thrombotic microangiopathy: a retrospective study of the Paediatric Diseases and Inborn Errors Working Parties of the European Society of Blood and Marrow Transplantation by Yeates, L, Slatter, M A, Bonanomi, S, Lim, F L W I, Ong, S Y, Dalissier, A, Barberi, W, Shulz, A, Duval, M, Heilmann, C, Willekens, A, Hwang, W H Y, Uderzo, C, Bader, P, Gennery, A R

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Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks by Willekens, Stefanie M. A., Van Weehaeghe, Donatienne, Van Damme, Philip, Van Laere, Koen

“…During the past decades, extensive efforts have been made to expand the knowledge of amyotrophic lateral sclerosis (ALS). However, clinical translation of this…”
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An MR-based brain template and atlas for optical projection tomography and light sheet fluorescence microscopy in neuroscience by Willekens, Stefanie M A, Morini, Federico, Mediavilla, Tomas, Nilsson, Emma, Orädd, Greger, Hahn, Max, Chotiwan, Nunya, Visa, Montse, Berggren, Per-Olof, Ilegems, Erwin, Överby, Anna K, Ahlgren, Ulf, Marcellino, Daniel

“…Optical Projection Tomography (OPT) and light sheet fluorescence microscopy (LSFM) are high resolution optical imaging techniques, ideally suited for ex vivo…”
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Liver Kupffer cells rapidly remove red blood cell–derived vesicles from the circulation by scavenger receptors by Willekens, Frans L.A., Werre, Jan M., Kruijt, J.Kar, Roerdinkholder-Stoelwinder, Bregt, Groenen-Döpp, Yvonne A.M., van den Bos, Annegeet G., Bosman, Giel J.C.G.M., van Berkel, Theo J.C.

“…Previous studies have shown that during the lifespan of red blood cells (RBCs) 20% of hemoglobin is lost by shedding of hemoglobin-containing vesicles…”
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Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin by Willekens, Stefanie M. A., Joosten, Lieke, Boerman, Otto C., Balhuizen, Alexander, Eizirik, Decio L., Gotthardt, Martin, Brom, Maarten

“…Purpose Noninvasive beta cell mass (BCM) quantification is a crucial tool to understand diabetes development and progression. [ 111 In]exendin is a promising…”
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Non-invasive in vivo determination of viable islet graft volume by 111In-exendin-3 by Eter, Wael A., Van der Kroon, Inge, Andralojc, Karolina, Buitinga, Mijke, Willekens, Stefanie M. A., Frielink, Cathelijne, Bos, Desiree, Joosten, Lieke, Boerman, Otto C., Brom, Maarten, Gotthardt, Martin

“…Pancreatic islet transplantation is a promising therapy for patients with type 1 diabetes. However, the duration of long-term graft survival is limited due to…”
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A Quantitative Evaluation of Joint Activity and Attenuation Reconstruction in TOF PET/MR Brain Imaging by Rezaei, Ahmadreza, Schramm, Georg, Willekens, Stefanie M A, Delso, Gaspar, Van Laere, Koen, Nuyts, Johan

“…Time-of-flight (TOF) PET data provide an effective means for attenuation correction (AC) when no (or incomplete or inaccurate) attenuation information is…”
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Hemoglobin loss from erythrocytes in vivo results from spleen-facilitated vesiculation by Willekens, Frans L.A., Roerdinkholder-Stoelwinder, Bregt, Groenen-Döpp, Yvonne A.M., Bos, Harry J., Bosman, Giel J.C.G.M., van den Bos, Annegeet G., Verkleij, Arie J., Werre, Jan M.

“…Previous studies have shown that approximately 20% of hemoglobin is lost from circulating red blood cells (RBCs), mainly during the second half of the cells'…”
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Regional Accuracy of ZTE-Based Attenuation Correction in Static [18F]FDG and Dynamic [18F]PE2I Brain PET/MR by Schramm, Georg, Koole, Michel, Willekens, Stefanie M. A., Rezaei, Ahmadreza, Van Weehaeghe, Donatienne, Delso, Gaspar, Peeters, Ronald, Mertens, Nathalie, Nuyts, Johan, Van Laere, Koen

“…Accurate MR-based attenuation correction (MRAC) is essential for quantitative PET/MR imaging of the brain. In this study, we analyze the regional bias caused…”
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The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation by Bosman, Giel J.C.G.M., Lasonder, Edwin, Groenen-Döpp, Yvonne A.M., Willekens, Frans L.A., Werre, Jan M.

“…Vesicle formation is an integral part of the physiological erythrocyte aging process. Recent biophysical and immunochemical data have suggested that vesicles…”
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Susceptibility to hyperosmotic stress-induced phosphatidylserine exposure increases during red blood cell storage by Bosman, Giel J.C.G.M., Cluitmans, Judith C.A., Groenen, Yvonne A.M., Werre, Jan M., Willekens, Frans L.A., Novotný, Vĕra M.J.

“…BACKGROUND: During storage of red blood cell (RBCs) before transfusion, RBCs undergo a series of structural and functional changes that include the exposure of…”
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SPECT of Transplanted Islets of Langerhans by Dopamine 2 Receptor Targeting in a Rat Model by Willekens, Stefanie M. A, van der Kroon, Inge, Joosten, Lieke, Frielink, Cathelijne, Boerman, Otto C, van den Broek, Sebastiaan A. M. W, Brom, Maarten, Gotthardt, Martin

“…Pancreatic islet transplantation can be a more permanent treatment for type 1 diabetes compared to daily insulin administration. Quantitative and longitudinal…”
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Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [ 123I]IBZM by Willekens, Stefanie M. A., van der Kroon, Inge, Bos, Desirée, Joosten, Lieke, Frielink, Cathelijne, Boerman, Otto C., Brom, Maarten, Gotthardt, Martin

“…A non‐invasive imaging method to monitor islet grafts could provide novel and improved insight into the fate of transplanted islets and, potentially, monitor…”
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From Mice to Humans: The Exocrine Pancreas Does Not Matter in Human GLP-1 Receptor Imaging by Gotthardt, Martin, Joosten, Lieke, Jansen, Theodorus J P, Brom, Maarten, Boss, Marti, Willekens, Stefanie M A

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Characterization of 111In-labeled Glucose-Dependent Insulinotropic Polypeptide as a Radiotracer for Neuroendocrine Tumors by Willekens, Stefanie M. A., Joosten, Lieke, Boerman, Otto C., Brom, Maarten, Gotthardt, Martin

“…Somatostatin receptor targeting is considered the standard nuclear medicine technique for visualization of neuroendocrine tumors (NET). Since not all NETs…”
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Heterozygous alpha-i antitrypsin deficiency as a co-factor in the development of chronic liver disease: a review by KOK, K. F, WAHAB, P. J, HOUWEN, R. H. J, DRENTH, J. P. H, DE MAN, R. A, VAN HOEK, B, MEIJER, J. W. R, WILLEKENS, F. L. A, DE VRIES, R. A

“…Alpha-I antitrypsin (AIAT) is an acute-phase protein that is produced in liver cells. AIAT deficiency is a hereditary disease which is defined by the hepatic…”
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Non-invasive in vivo determination of viable islet graft volume by 111 In-exendin-3 by Eter, Wael A, Van der Kroon, Inge, Andralojc, Karolina, Buitinga, Mijke, Willekens, Stefanie M A, Frielink, Cathelijne, Bos, Desiree, Joosten, Lieke, Boerman, Otto C, Brom, Maarten, Gotthardt, Martin

“…Pancreatic islet transplantation is a promising therapy for patients with type 1 diabetes. However, the duration of long-term graft survival is limited due to…”
Get full text