Search Results - "Willbanks, Amber"

EMT and tumor metastasis by Heerboth, Sarah, Housman, Genevieve, Leary, Meghan, Longacre, Mckenna, Byler, Shannon, Lapinska, Karolina, Willbanks, Amber, Sarkar, Sibaji

“…EMT and MET comprise the processes by which cells transit between epithelial and mesenchymal states, and they play integral roles in both normal development…”
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RNA Epigenetics: Fine-Tuning Chromatin Plasticity and Transcriptional Regulation, and the Implications in Human Diseases by Willbanks, Amber, Wood, Shaun, Cheng, Jason X

“…Chromatin structure plays an essential role in eukaryotic gene expression and cell identity. Traditionally, DNA and histone modifications have been the focus…”
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Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women by Duggan, Catherine, Yu, Ming, Willbanks, Amber R., Tapsoba, Jean de Dieu, Wang, Ching-Yun, Grady, William M., McTiernan, Anne

“…Physical activity reduces risk of colon cancer by 20-30%. Aberrant methylation patterns are common epigenetic alterations in colorectal adenomas, and cancers…”
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A Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian Cancer Related to Tumorigenesis by Longacre, Mckenna, Snyder, Nicole A, Housman, Genevieve, Leary, Meghan, Lapinska, Karolina, Heerboth, Sarah, Willbanks, Amber, Sarkar, Sibaji

“…Breast cancer persists as the most common cause of cancer death in women worldwide. Ovarian cancer is also a significant source of morbidity and mortality, as…”
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Dysfunctional epigenetic aging of the normal colon and colorectal cancer risk by Wang, Ting, Maden, Sean K, Luebeck, Georg E, Li, Christopher I, Newcomb, Polly A, Ulrich, Cornelia M, Joo, Ji-Hoon E, Buchanan, Daniel D, Milne, Roger L, Southey, Melissa C, Carter, Kelly T, Willbanks, Amber R, Luo, Yanxin, Yu, Ming, Grady, William M

“…Chronological age is a prominent risk factor for many types of cancers including colorectal cancer (CRC). Yet, the risk of CRC varies substantially between…”
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The Evolution of Epigenetics: From Prokaryotes to Humans and Its Biological Consequences by Willbanks, Amber, Leary, Meghan, Greenshields, Molly, Tyminski, Camila, Heerboth, Sarah, Lapinska, Karolina, Haskins, Kathryn, Sarkar, Sibaji

“…The evolution process includes genetic alterations that started with prokaryotes and now continues in humans. A distinct difference between prokaryotic…”
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Rapid Analysis and Prediction of Drug Resistance in Leukemia By Novel Nascent RNA-Driven Flow Imaging Technologies and Biomarkers by Wood, Shaun, Willbanks, Amber, Cheng, Jason Xiaojun

“…Background: Drug selectivity and resistance is a major obstacle to successful cancer therapy, including traditional chemotherapies (Vasan, N. et al. Nature…”
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RNA Cytosine Methyltransferases NSUN1 and NSUN2 Mediate the Lineage-Associated Resistance to Venetoclax in Leukemia by Wood, Shaun, Willbanks, Amber, Cheng, Jason Xiaojun

“…Background: Combinations of venetoclax/ABT-199, a small molecule that selectively inhibits anti-apoptotic protein BCL2, with hypomethylating agents (HMAs),…”
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Harnessing the Systemic Biology of Functional Decline and Cachexia to Inform more Holistic Therapies for Incurable Cancers by Willbanks, Amber, Seals, Mina, Karmali, Reem, Roy, Ishan

“…Options for treatment of incurable cancer remain scarce and are largely focused on limited therapeutic mechanisms. A new approach specific to advanced cancers…”
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Novel RNA epigenetics-driven technologies for rapid prediction of cancer drug resistance by Wood, Shaun, Willbanks, Amber, Tang, Derrick, Arber, Daniel A, Oakes, Scott, Shammo, Jamile M., Odenike, Olatoyosi, Stock, Wendy, Larson, Richard, Cheng, Jason X

“…e19001 Background: The human genome comprises ~99% non-coding DNA sequences (ncDNAs), most of which are actively transcribed into various forms of non-coding…”
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Low-dose orthotopic cancer implantation permits measurement of longitudinal functional changes associated with cachexia by Roy, Ishan, Binder-Markey, Benjamin, Willbanks, Amber, Sychowski, Danielle, Phipps, Tenisha, Barber, Addison, McAllister, Donna, D'Andrea, Dominic, Franz, Colin K, Pichika, Rajeswari, Dwinell, Michael B, Lieber, Richard L

“…Progressive functional decline is a key element of cancer-associated cachexia. Major barriers to translating preclinical therapies into the clinic include lack…”
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The Effects of Histone Deacetylase Inhibitor and Calpain Inhibitor Combination Therapies on Ovarian Cancer Cells by Lapinska, Karolina, Housman, Genevieve, Byler, Shannon, Heerboth, Sarah, Willbanks, Amber, Oza, Anuja, Sarkar, Sibaji

“…Ovarian cancer is difficult to treat due to absence of selective drugs and tendency of platinum drugs to promote resistance. Combination therapy using…”
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Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis by Yu, Ming, Maden, Sean K, Stachler, Matthew, Kaz, Andrew M, Ayers, Jessica, Guo, Yuna, Carter, Kelly T, Willbanks, Amber, Heinzerling, Tai J, O'Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K, Chak, Amitabh, Elliott, Robin, Willis, Joseph E, Markowitz, Sanford D, Grady, William M

“…To identify and characterise DNA methylation subtypes in oesophageal adenocarcinoma (EAC) and its precursor Barrett's oesophagus (BE). We performed genome-wide…”
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Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia by Yu, Ming, Moinova, Helen R, Willbanks, Amber, Cannon, Victoria K, Wang, Ting, Carter, Kelly, Kaz, Andrew, Reddi, Deepti, Inadomi, John, Luebeck, Georg, Iyer, Prasad G, Canto, Marcia I, Wang, Jean S, Shaheen, Nicholas J, Thota, Prashanti N, Willis, Joseph E, LaFramboise, Thomas, Chak, Amitabh, Markowitz, Sanford D, Grady, William M

“…Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an…”
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