Search Results - "Willard, Nicholas"

Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas by Amani, Vladimir, Riemondy, Kent A, Fu, Rui, Griesinger, Andrea M, Grimaldo, Enrique, De Sousa, Graziella Ribeiro, Gilani, Ahmed, Hemenway, Molly, Foreman, Nicholas K, Donson, Andrew M, Willard, Nicholas

“…Plexiform neurofibroma (PN) is a leading cause of morbidity in children with the genetic condition Neurofibromatosis Type 1 (NF1), often disfiguring or…”
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Hypocomplementemic Atypical IgA Vasculitis: A Case Report by Chan, Melvin, Hanna, Melisha Gayle, Willard, Nicholas, Treece, Amy, Dixon, Bradley Patton

“…IgA vasculitis (IgAV, also known as Henoch-Schönlein purpura or HSP) is a vasculitis of small vessels involving multiple organs, particularly of the joints,…”
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Molecular and clinicopathologic characteristics of CNS embryonal tumors with BRD4::LEUTX fusion by Andreiuolo, Felipe, Ferrone, Christina K, Rajan, Sharika, Perry, Arie, Guney, Ekin, Cham, Elaine, Giannini, Caterina, Toland, Angus, Willard, Nicholas, de Souza, Andrea Silveira, Dazelle, Karen, Chung, Hye-Jung, Singh, Omkar, Conway, Kyle, Coley, Nicholas, Dampier, Christopher, Abdullaev, Zied, Pratt, Drew, Cimino, Patrick J, Quezado, Martha, Aldape, Kenneth

“…Central nervous system (CNS) embryonal tumors are a heterogeneous group of high-grade malignancies, and the increasing clinical use of methylation profiling…”
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Diverse clinical and histopathologic features of cutaneous post‐transplant lymphoproliferative disorders: A presentation of two cases by Roberts, Sammie J, McNally, Brandon, Rosser, Julie A, Willard, Nicholas, Golitz, Loren, Wisell, Joshua

“…Heterogeneous lymphoproliferative disorders occurring in the post‐transplant setting are considered together as post‐transplant lymphoproliferative disorders…”
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Concurrent ependymal and ganglionic differentiation in a subset of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement by Lee, Julieann C, Koo, Selene C, Furtado, Larissa V, Breuer, Alex, Eldomery, Mohammad K, Bag, Asim K, Stow, Pat, Rose, Gary, Larkin, Trisha, Sances, Rick, Kleinschmidt-DeMasters, Bette K, Bodmer, Jenna L, Willard, Nicholas, Gokden, Murat, Dahiya, Sonika, Roberts, Kaleigh, Bertrand, Kelsey C, Moreira, Daniel C, Robinson, Giles W, Mo, Jun Qin, Ellison, David W, Orr, Brent A

“…Neuroepithelial tumors with fusion of PLAGL1 or amplification of PLAGL1/PLAGL2 have recently been described often with ependymoma-like or embryonal histology…”
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High‐level gonosomal mosaicism for a pathogenic non‐coding CNV deletion of the lung‐specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV by Yıldız Bölükbaşı, Esra, Karolak, Justyna A., Szafranski, Przemyslaw, Gambin, Tomasz, Willard, Nicholas, Abman, Steven H., Galambos, Csaba, Kinsella, John P., Stankiewicz, Paweł

“…Background Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) results from haploinsufficiency of the mesenchymal transcription factor…”
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Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma by Griesinger, Andrea M., Riemondy, Kent, Eswaran, Nithyashri, Donson, Andrew M., Willard, Nicholas, Prince, Eric W., Paine, Simon M.L., Bowes, Georgia, Rheaume, John, Chapman, Rebecca J., Ramage, Judith, Jackson, Andrew, Grundy, Richard G., Foreman, Nicholas K., Ritzmann, Timothy A.

“…Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the cellular heterogeneity of EPN tumors, identifying multiple…”
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Proteomic Identification and Quantification of Snake Venom Biomarkers in Venom and Plasma Extracellular Vesicles by Willard, Nicholas Kevin, Salazar, Emelyn, Oyervides, Fabiola Alejandra, Wiebe, Cierra Siobhrie, Ocheltree, Jack Sutton, Cortez, Mario, Perez, Ricardo Pedro, Markowitz, Harry, Iliuk, Anton, Sanchez, Elda Eliza, Suntravat, Montamas, Galan, Jacob Anthony

“…The global exploration of snakebites requires the use of quantitative omics approaches to characterize snake venom as it enters into the systemic circulation…”
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ETMR-31. A UNIQUE CASE OF CNS DIFFUSE, NON-SYSTEMIC ALK+ HISTIOCYTOSIS IN A PEDIATRIC PATIENT by DeMarsh, Samantha J, Orr, Brent, Willard, Nicholas, Dahl, Nathan

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Panel Sequencing for Targeted Therapy Selection in Solid Tumors by Willard, Nicholas, Sholl, Lynette, Aisner, Dara

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Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement by Johnson, Mckinzie, Willard, Nicholas, Pan, Zenggang

“…Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma, with most cases harboring ALK gene rearrangement (ALK + ALCL); however, 20-50%…”
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Abdominal wall endometrioma in the setting of prior vaginostomy tube drainage of hematometrocolpos by Drake, Erin, Willard, Nicholas, Treece, Amy, Bischoff, Andrea, Alaniz, Veronica

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ETMR-22. IDENTIFICATION OF 5-FLUROURACIL AS A SELECTIVE THERAPY IN A NOVEL EP300::BCOR FUSION GLIOMA TUMOR MODEL by Donson, Andrew M, Amani, Vladimir, Griesinger, Andrea M, Calzadilla, Annaliese, Grimaldo, Enrique, Willard, Nicholas, Foreman, Nicholas K, Mulcahy-Levy, Jean

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HGG-17. Novel Fusion in Congenital Brainstem Diffuse High-Grade Glioma by Norris, Gregory, Donson, Andrew, Milgrom, Sarah, Gaskell, Alisa, Willard, Nicholas, Foreman, Nicholas, Gilani, Ahmed, Dahl, Nathan

“…BACKGROUND: Infant-type hemispheric glioma, previously termed infantile glioblastoma multiforme, is a rare infantile neoplasm with improved survival and…”
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MEDB-44. Transcriptomic resolution of subgroup-specific medulloblastoma architecture by Willard, Nicholas, Riemondy, Kent, Griesinger, Andrea, Kaufman, Michael, Venkataraman, Sujatha, Foreman, Nicholas, Vibhakar, Rajeev, Donson, Andrew

“…Despite a growing understanding and stratification of medulloblastoma, it remains an aggressive childhood brain tumor with high morbidity and mortality…”
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EPEN-08. THE TREM1 POSITIVE HYPOXIC MYELOID SUBPOPULATION IN POSTERIOR FOSSA EPENDYMOMA by Willard, Nicholas, Donson, Andrew, Ritzmann, Timothy, Grundy, Richard, Jackson, Andrew, Hankinson, Todd, Griesinger, Andrea, Foreman, Nicholas

“…We have previously shown the importance of immune factors in posterior fossa ependymoma (PF EPN). Recently, we found eight transcriptionally unique…”
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Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma by Riemondy, Kent A, Venkataraman, Sujatha, Willard, Nicholas, Nellan, Anandani, Sanford, Bridget, Griesinger, Andrea M, Amani, Vladimir, Mitra, Siddhartha, Hankinson, Todd C, Handler, Michael H, Sill, Martin, Ocasio, Jennifer, Weir, Seth J, Malawsky, Daniel S, Gershon, Timothy R, Garancher, Alexandra, Wechsler-Reya, Robert J, Hesselberth, Jay R, Foreman, Nicholas K, Donson, Andrew M, Vibhakar, Rajeev

“…Abstract Background Medulloblastoma (MB) is a heterogeneous disease in which neoplastic cells and associated immune cells contribute to disease progression. We…”
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A New Monoclonal Band in a Patient with Refractory Multiple Myeloma by Willard, Nicholas, Bocsi, Gregary T

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PRES: Review of Histological Features by Willard, Nicholas, Honce, Justin M, Kleinschmidt-DeMasters, B K

“…Abstract Posterior reversible encephalopathy syndrome was described in 1996 as a clinical-neuroimaging entity characterized by parieto-occipital…”
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IMMU-10. TUMOR ASSOCIATED MYELOID CELLS DRIVE THE IMMUNOBIOLOGY OF HIGH RISK PEDIATRIC EPENDYMOMA by Griesinger, Andrea, Riemondy, Kent, Eswaran, Nithyashri, Donson, Andrew, Willard, Nicholas, Paine, Simon, Bowes, Georgia, Rheaume, John, Chapman, Rebecca, Ramage, Judith, Jackson, Andrew, Grundy, Richard, Foreman, Nicholas, Ritzmann, Timothy

“…Molecular profiling of pediatric ependymoma (EPN) has previously identified discrete neoplastic subpopulations, of which Mesenchymal EPN Cells (MEC)…”
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