Search Results - "Wilks, Logan R"
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Standardizing the skin tape stripping method for sensitization and using it to create a mouse model of peanut allergy
Published in International journal of pharmaceutics (05-09-2024)“…[Display omitted] Animal models for food allergies serve as crucial tools in understanding allergy mechanisms and assessing the efficacy of potential…”
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Generation of Broad Protection against Influenza with Di-Tyrosine-Cross-Linked M2e Nanoclusters
Published in ACS infectious diseases (10-05-2024)“…Tyrosine cross-linking has recently been used to produce nanoclusters (NCs) from peptides to enhance their immunogenicity. In this study, NCs were generated…”
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Protein–Protein Interactions of Highly Concentrated Monoclonal Antibody Solutions via Static Light Scattering and Influence on the Viscosity
Published in The journal of physical chemistry. B (31-01-2019)“…The ability to design and formulate mAbs to minimize attractive interactions at high concentrations is important for protein processing, stability, and…”
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Relating Collective Diffusion, Protein–Protein Interactions, and Viscosity of Highly Concentrated Monoclonal Antibodies through Dynamic Light Scattering
Published in Industrial & engineering chemistry research (18-12-2019)“…To understand and predict the viscosities of highly concentrated monoclonal antibody (mAb) solutions, it is important to characterize the protein–protein…”
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X‑ray Scattering and Coarse-Grained Simulations for Clustering and Interactions of Monoclonal Antibodies at High Concentrations
Published in The journal of physical chemistry. B (27-06-2019)“…Attractive protein–protein interactions (PPI) in concentrated monoclonal antibody (mAb) solutions may lead to reversible oligomers (clusters) that impact…”
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Tyrosine-Based Cross-Linking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A
Published in ACS infectious diseases (10-09-2021)“…A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine cross-linking reaction…”
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Peptide Cross-Linking Using Tyrosine Residues Facilitated by an Exogenous Nickel–Histidine Complex: A Facile Approach for Enhancing Vaccine-Specific Immunogenicity
Published in ACS infectious diseases (09-12-2022)“…An improved method for the generation of peptide vaccines using di-tyrosine cross-linking is described. The conserved ion channel peptide, M2e, of influenza A…”
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Tyrosine-based Crosslinking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A
Published in ACS infectious diseases (25-08-2021)“…A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine crosslinking reaction. A…”
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