Search Results - "Wilks, Donna"

Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats by Reznick, Jane, Preston, Elaine, Wilks, Donna L, Beale, Susan M, Turner, Nigel, Cooney, Gregory J

“…Energy metabolism follows a diurnal pattern responding to the light/dark cycle and food availability. This study investigated the impact of restricting feeding…”
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Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle by Boden, Michael J, Brandon, Amanda E, Tid-Ang, Jennifer D, Preston, Elaine, Wilks, Donna, Stuart, Ella, Cleasby, Mark E, Turner, Nigel, Cooney, Gregory J, Kraegen, Edward W

“…Elevated mitochondrial reactive oxygen species have been suggested to play a causative role in some forms of muscle insulin resistance. However, the extent of…”
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Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling by Small, Lewin, Brandon, Amanda E., Parker, Benjamin L., Deshpande, Vinita, Samsudeen, Azrah F., Kowalski, Greg M., Reznick, Jane, Wilks, Donna L., Preston, Elaine, Bruce, Clinton R., James, David E., Turner, Nigel, Cooney, Gregory J.

“…Energy metabolism and insulin action follow a diurnal rhythm. It is therefore important that investigations into dysregulation of these pathways are relevant…”
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Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo by Parkes, Heidi A, Preston, Elaine, Wilks, Donna, Ballesteros, Mercedes, Carpenter, Lee, Wood, Leonie, Kraegen, Edward W, Furler, Stuart M, Cooney, Gregory J

“…Accumulation of intracellular lipid in obesity is associated with metabolic disease in many tissues including liver. Storage of fatty acid as triglyceride (TG)…”
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Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats by Kraegen, Edward W, Saha, Asish K, Preston, Elaine, Wilks, Donna, Hoy, Andrew J, Cooney, Gregory J, Ruderman, Neil B

“…Glucose infusion in rats for 1-4 days results in insulin resistance and increased triglyceride, whole tissue long-chain fatty acyl-CoA (LCA-CoA), and…”
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Chronic Central Melanocortin-4 Receptor Antagonism and Central Neuropeptide-Y Infusion in Rats Produce Increased Adiposity by Divergent Pathways by BARAN, Katherine, PRESTON, Elaine, WILKS, Donna, COONEY, Gregory J, KRAEGEN, Edward W, SAINSBURY, Amanda

“…Chronic Central Melanocortin-4 Receptor Antagonism and Central Neuropeptide-Y Infusion in Rats Produce Increased Adiposity by Divergent Pathways Katherine…”
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Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice by Holt, Lowenna J, Brandon, Amanda E, Small, Lewin, Suryana, Eurwin, Preston, Elaine, Wilks, Donna, Mokbel, Nancy, Coles, Chantal A, White, Jason D, Turner, Nigel, Daly, Roger J, Cooney, Gregory J

“…Grb10 is an adaptor-type signaling protein most highly expressed in tissues involved in insulin action and glucose metabolism, such as muscle, pancreas, and…”
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Acute or Chronic Upregulation of Mitochondrial Fatty Acid Oxidation Has No Net Effect on Whole-Body Energy Expenditure or Adiposity by Hoehn, Kyle L., Turner, Nigel, Swarbrick, Michael M., Wilks, Donna, Preston, Elaine, Phua, Yuwei, Joshi, Himani, Furler, Stuart M., Larance, Mark, Hegarty, Bronwyn D., Leslie, Simon J., Pickford, Russell, Hoy, Andrew J., Kraegen, Edward W., James, David E., Cooney, Gregory J.

“…Activation of AMP-activated protein kinase (AMPK) is thought to convey many of the beneficial effects of exercise via its inhibitory effect on acetyl-CoA…”
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Regulation of the nuclear hormone receptor nur77 in muscle: Influence of exercise-activated pathways in vitro and obesity in vivo by Kanzleiter, Timo, Wilks, Donna, Preston, Elaine, Ye, Jiming, Frangioudakis, Georgia, Cooney, Gregory James

“…Regular physical exercise is well known to improve glucose and lipid metabolism in skeletal muscle. However, the transcription factors regulating these…”
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Sialic Acid Modification of Adiponectin Is Not Required for Multimerization or Secretion but Determines Half-Life in Circulation by Richards, Ayanthi A, Colgrave, Michelle L, Zhang, Jialiang, Webster, Julie, Simpson, Fiona, Preston, Elaine, Wilks, Donna, Hoehn, Kyle L, Stephenson, Matthew, Macdonald, Graeme A, Prins, John B, Cooney, Gregory J, Xu, Aimin, Whitehead, Jonathan P

“…Adiponectin is an adipocyte-secreted, insulin-sensitizing hormone the circulating levels of which are reduced in conditions of insulin resistance and diabetes…”
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Central neuropeptide Y infusion and melanocortin 4 receptor antagonism inhibit thyrotropic function by divergent pathways by Preston, Elaine, Cooney, Gregory J, Wilks, Donna, Baran, Katherine, Zhang, Lei, Kraegen, Edward W, Sainsbury, Amanda

“…Abstract Weight loss inhibits thyrotropic function and reduces metabolic rate, thereby contributing to weight regain. Under negative energy balance there is an…”
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Central but Not Peripheral Glucocorticoid Infusion in Adrenalectomized Male Rats Increases Basal and Substrate-Induced Insulinemia through a Parasympathetic Pathway by Sainsbury, Amanda, Wilks, Donna, Cooney, Gregory J.

“…Objective: Glucocorticoids acting through the central nervous system are postulated to play a role in the hyperinsulinemia and increased adiposity of obesity…”
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