Search Results - "Wilkins, RC"

Analysis of chromosome damage for biodosimetry using imaging flow cytometry by Beaton, L.A., Ferrarotto, C., Kutzner, B.C., McNamee, J.P., Bellier, P.V., Wilkins, R.C.

“…•The dicentric chromosome assay is the gold standard for biodosimetry.•It is now possible to adapt this assay to an automated imaging cytometry method.•We…”
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SU‐E‐T‐06: Investigating in Vitro Gamma‐H2AX Response and Chromosome Damage in Human Lymphocytes and Lymphocyte Subsets for Biomarkers of Radiation Sensitivity by Beaton, LA, Ferrarotto, C, Ringuette, N, Malone, S, Samiee, S, Wilkins, RC

“…Purpose: To examine the in vitro gamma‐H2AX response in lymphocytes and lymphocyte subsets from patients who have shown severe radiosensitive response (severe…”
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The Internet’s Role in a Biodosimetric Response to a Radiation Mass Casualty Event by Sugarman, S.L, Livingston, G.K, Stricklin, D.L, Abbott, M.G, Wilkins, R.C, Romm, H, Oestreicher, U, Yoshida, M.A, Miura, T, Moquet, J.E, Di Giorgio, M, Ferrarotto, C, Gross, G.A, Christiansen, M.E, Hart, C.L, Christensen, D.M

“…ABSTRACTResponse to a large-scale radiological incident could require timely medical interventions to minimize radiation casualties. Proper medical care…”
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Sci—Thurs AM: YIS—03: Development and Characterization of an in Vitro Alpha Radiation Exposure System for the Purpose of Cell Culture by Beaton, LA, Stocki, TJ, Chauhan, V, Wilkins, RC

“…Radon gas ( 222 Rn ), a major component of background radiation, is an alpha emitter with progeny that also emit alpha particles. It is ubiquitous in our…”
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Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation by Wilkins, R.C, Lis, J.T

“…GAGA factor (GAF) binds to specific DNA sequences and participates in a complex spectrum of chromosomal activities. Products of the Trithorax-like locus (Trl),…”
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GAGA factor binding to DNA via a single trinucleotide sequence element by Wilkins, R.C, Lis, J.T

“…GAGA transcription factor (GAF) is an essential protein in Drosophila, important for the transcriptional regulation of numerous genes. GAF binds to GA repeats…”
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Effect of pro-inflammatory cytokines on spontaneous apoptosis in leukocyte sub-sets within a whole blood culture by McNamee, J.P., Bellier, P.V., Kutzner, B.C., Wilkins, R.C.

“…Pro-inflammatory cytokines are known to affect apoptosis in human peripheral blood cells. Neutrophils, which are an essential component of the immune response…”
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Silver-stained comet assay for detection of apoptosis by Kizilian, N, Wilkins, R C, Reinhardt, P, Ferrarotto, C, McLean, J R, McNamee, J P

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Differential apoptotic response to ionizing radiation in subpopulations of human white blood cells by Wilkins, R.C., Wilkinson, D., Maharaj, H.P., Bellier, P.V., Cybulski, M.B., McLean, J.R.N.

“…The purpose of this paper is to characterize the apoptotic response of various subpopulations of human white blood cells after in vitro exposure to ionizing…”
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DNA distortion and multimerization: novel functions of the glutamine-rich domain of GAGA factor by Wilkins, R.C, Lis, J.T

“…GAGA factor (GAF) is an essential protein in Drosophila melanogaster, important for the transcriptional regulation of numerous genes. The effect of GAF on…”
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A comparison of T 2-weighted magnitude and phase imaging for measuring the arterial input function in the rat aorta following intravenous injection of gadolinium contrast agent by Cron, Greg O., Wallace, Julia C., Stevens, W. Dale, Fortin, Teresa, Pappas, Bruce A., Wilkins, Ruth C., Kelcz, Frederick, Santyr, Giles E.

“…The arterial input function (AIF) is important for quantitative MR imaging perfusion experiments employing Gd contrast agents. This study compared the accuracy…”
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The effect of the ratio of CD4 + to CD8 + T-cells on radiation-induced apoptosis in human lymphocyte subpopulations by Wilkins, R. C., Kutzner, B. C., Truong, M., McLean, J. R. N.

“…Purpose: Apoptosis occurs spontaneously in cultured human peripheral blood lymphocytes but is enhanced by exposure to ionizing radiation. Subpopulations of…”
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Distribution of GAGA protein on Drosophila genes in vivo by O'Brien, T, Wilkins, R C, Giardina, C, Lis, J T

“…GAGA protein binds specific CT.GA-rich DNA sequences in vitro, and many of these sequences are required for transcription in vivo. GAGA protein has been…”
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No Effect of 60 Hz Electromagnetic Fields on MYC or β-Actin Expression in Human Leukemic Cells by Lacy-Hulbert, Adam, Wilkins, Roger C., Hesketh, T. Robin, Metcalfe, James C.

“…Epidemiological studies have shown weak correlations between exposure to extremely low-frequency electromagnetic fields (ELF EMFs) and the incidence of several…”
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Increased FITC fluorescence on LPS stimulated neutrophils cultured in whole blood by Wilkins, R.C., Bellier, P.V., Kutzner, B.C., McNamee, J.P.

“…Recently, it has been observed that Annexin V labelling of phosphatidylserine (PS) on non-apoptotic cells can vary in different leukocyte populations and with…”
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Cancer risk and electromagnetic fields by Lacy-Hulbert, Adam, Wilkins, Roger C, Hesketh, T. Robin, Metcalfe, James C

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Analysis of radiation‐induced apoptosis in human lymphocytes: Flow cytometry using Annexin V and propidium iodide versus the neutral comet assay by Wilkins, R.C., Kutzner, B.C., Truong, M., Sanchez‐Dardon, J., McLean, J.R.N.

“…Background The neutral comet assay was devised to measure double‐stranded DNA breaks, but it has also been used to measure apoptosis based on its…”
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Silver-stained "comets" for the detection of radiation-induced apoptosis: automated assay by Gibbons, D.T., Johnson, F., Wilkins, R.C., Kizilian, N., McLean, J.R.N.

“…This paper reviews the development of a bioassay that uses apoptosis (a form of cell death) to directly measure the response of cells to a physical or chemical…”
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