Search Results - "Wilkins, H."

Reslizumab for Poorly Controlled, Eosinophilic Asthma: A Randomized, Placebo-controlled Study by CASTRO, Mario, MATHUR, Sameer, HARGREAVE, Frederick, BOULET, Louis-Philippe, FANG XIE, YOUNG, James, JEFFREY WILKINS, H, HENKEL, Timothy, NAIR, Parameswaran

“…Eosinophilic asthma is a phenotype of asthma characterized by the persistence of eosinophils in the airways. IL-5 is involved in the activation and survival of…”
Get full text

Fully automated endoscopic disease activity assessment in ulcerative colitis by Yao, Heming, Najarian, Kayvan, Gryak, Jonathan, Bishu, Shrinivas, Rice, Michael D., Waljee, Akbar K., Wilkins, H. Jeffrey, Stidham, Ryan W.

“…Endoscopy is essential for disease assessment in ulcerative colitis (UC), but subjectivity threatens accuracy and precision. We aimed to pilot a fully…”
Get full text

Reslizumab in children and adolescents with eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial by Spergel, Jonathan M., MD, PhD, Rothenberg, Marc E., MD, PhD, Collins, Margaret H., MD, Furuta, Glenn T., MD, Markowitz, Jonathan E., MD, Fuchs, George, MD, O’Gorman, Molly A., MD, Abonia, Juan Pablo, MD, Young, James, MS, Henkel, Timothy, MD, PhD, Wilkins, H. Jeffrey, MD, Liacouras, Chris A., MD

“…Background Eosinophilic esophagitis is a chronic allergic disease with insufficient treatment options. Results from animal studies suggest that IL-5 induces…”
Get full text

Diversity and inclusion for the All of Us research program: A scoping review by Mapes, Brandy M, Foster, Christopher S, Kusnoor, Sheila V, Epelbaum, Marcia I, AuYoung, Mona, Jenkins, Gwynne, Lopez-Class, Maria, Richardson-Heron, Dara, Elmi, Ahmed, Surkan, Karl, Cronin, Robert M, Wilkins, Consuelo H, Pérez-Stable, Eliseo J, Dishman, Eric, Denny, Joshua C, Rutter, Joni L

“…The All of Us Research Program (All of Us) is a national effort to accelerate health research by exploring the relationship between lifestyle, environment, and…”
Get full text

Equitable Pandemic Preparedness and Rapid Response: Lessons from COVID-19 for Pandemic Health Equity by Alberti, Philip M, Lantz, Paula M, Wilkins, Consuelo H

“…The novel coronavirus pandemic has set in high relief the entrenched health, social, racial, political, and economic inequities within American society as the…”
Get more information

Relative predictive value of sociodemographic factors for chronic diseases among All of Us participants: a descriptive analysis by Kunnath, Ansley J, Sack, Daniel E, Wilkins, Consuelo H

“…Although sociodemographic characteristics are associated with health disparities, the relative predictive value of different social and demographic factors…”
Get full text

Phase 1 Open-Label, Multicenter Study of First-in-Class RORγ Agonist LYC-55716 (Cintirorgon): Safety, Tolerability, and Preliminary Evidence of Antitumor Activity by Mahalingam, Devalingam, Wang, Judy S, Hamilton, Erika P, Sarantopoulos, John, Nemunaitis, John, Weems, Garry, Carter, Laura, Hu, Xiao, Schreeder, Marshall, Wilkins, H Jeffrey

“…Transcription factor retinoic acid receptor-related orphan receptor γ (RORγ) regulates type 17 effector T-cell differentiation and function and is key to…”
Get full text

Randomized, double-blind, controlled trial of human anti-LIGHT monoclonal antibody in COVID-19 acute respiratory distress syndrome by Perlin, David S, Neil, Garry A, Anderson, Colleen, Zafir-Lavie, Inbal, Raines, Shane, Ware, Carl F, Wilkins, H Jeffrey

“…BACKGROUNDSevere coronavirus disease 2019 (COVID-19) is associated with a dysregulated immune response, which can result in cytokine-release syndrome and acute…”
Get full text

CARBON CHAINS AND METHANOL TOWARD EMBEDDED PROTOSTARS by Graninger, Dawn M, Wilkins, Olivia H, Oberg, Karin I

“…ABSTRACT Large interstellar organic molecules are potential precursors of prebiotic molecules. Their formation pathways and chemical relationships with one…”
Get full text

Barriers and facilitators to dissemination and adoption of precision medicine among Hispanics/Latinos by Canedo, Juan R, Wilkins, Consuelo H, Senft, Nicole, Romero, Araceli, Bonnet, Kemberlee, Schlundt, David

“…With the rapid advances in gene technologies in recent years, the potential benefits of precision medicine (PM) may spread unevenly to disadvantaged…”
Get full text

Gas-phase Ortho-to-para Ratio of Formaldehyde Formed at Low Temperatures in Laboratory Ices by Yocum, K. M., Wilkins, O. H., Bardwell, J. C., Milam, S. N., Gerakines, P. A.

“…Abstract The ortho-to-para ratio (OPR) of formaldehyde (H 2 CO) has been used as a probe to estimate the formation temperature of molecules in interstellar,…”
Get full text

Factors influencing precision medicine knowledge and attitudes by Chakravarthy, Rohini, Stallings, Sarah C, Williams, Michael, Hollister, Megan, Davidson, Mario, Canedo, Juan, Wilkins, Consuelo H

“…Precision medicine holds great promise for improving health and reducing health disparities that can be most fully realized by advancing diversity and…”
Get full text

Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial by NEWHOUSE, P, KELLAR, K, AISEN, P, WHITE, H, WESNES, K, CODERRE, E, PFAFF, A, WILKINS, H, HOWARD, D, LEVIN, E. D

“…To preliminarily assess the safety and efficacy of transdermal nicotine therapy on cognitive performance and clinical status in subjects with mild cognitive…”
Get full text

Mitochondria, Cybrids, Aging, and Alzheimer's Disease by Swerdlow, R H, Koppel, S, Weidling, I, Hayley, C, Ji, Y, Wilkins, H M

“…Mitochondrial and bioenergetic function change with advancing age and may drive aging phenotypes. Mitochondrial and bioenergetic changes are also documented in…”
Get full text

Formative research to design a culturally-appropriate cancer clinical trial education program to increase participation of African American and Latino communities by Cunningham-Erves, Jennifer, Barajas, Claudia, Mayo-Gamble, Tilicia L, McAfee, Caree R, Hull, Pamela C, Sanderson, Maureen, Canedo, Juan, Beard, Katina, Wilkins, Consuelo H

“…Addressing knowledge deficiencies about cancer clinical trials and biospecimen donation can potentially improve participation among racial and ethnic…”
Get full text

Development and pilot implementation of guidelines for culturally tailored research recruitment materials for African Americans and Latinos by Cunningham-Erves, Jennifer, Kusnoor, Sheila V., Villalta-Gil, Victoria, Stallings, Sarah C., Ichimura, Jabari S., Israel, Tiffany L., Harris, Paul A., Wilkins, Consuelo H.

“…Abstract Background Previous studies support cultural tailoring of recruitment materials as a strategy to promote the enrollment of minoritized groups in…”
Get full text

Exploring the “Obesity Paradox” as a Correlate of Cognitive and Physical Function in Community-dwelling Black and White Older Adults by Skinner, Jeannine S., Abel, Willie Mae, McCoy, Katryna, Wilkins, Consuelo H.

“…The obesity paradox has been documented in aged populations, yet it remains unclear if this paradox persists for physical and cognitive outcomes in…”
Get full text

Adapting a conceptual framework to engage diverse stakeholders in genomic/precision medicine research by Watson, Karriem S., Cohn, Elizabeth G., Fair, Alecia, Menon, Usha, Szalacha, Laura A., Carpenter, Selena M., Wilkins, Consuelo H.

“…Introduction Genomic/precision medicine offers a remarkable opportunity to improve health and address health disparities. Genomic medicine is the study of…”
Get full text

Design and implementation of a massive open online course on enhancing the recruitment of minorities in clinical trials - Faster Together by Kusnoor, Sheila V, Villalta-Gil, Victoria, Michaels, Margo, Joosten, Yvonne, Israel, Tiffany L, Epelbaum, Marcia I, Lee, Patricia, Frakes, Elizabeth T, Cunningham-Erves, Jennifer, Mayers, Stephanie A, Stallings, Sarah C, Giuse, Nunzia B, Harris, Paul A, Wilkins, Consuelo H

“…Racial and ethnic minorities are often underrepresented in clinical trials, threatening the generalizability of trial results. Several factors may contribute…”
Get full text

A case of adherent Meckel’s diverticulum causing fatal strangulation by Wilkins, E. H

“…Reprints an article first published in this journal 100 years ago in which the author describes the case of a patient with diverticulum causing fatal…”
Get full text