Search Results - "Wilkins, Brendan P."

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium‐chain fatty acid receptor Gpr84 by Montgomery, Magdalene K., Osborne, Brenna, Brandon, Amanda E., O'Reilly, Liam, Fiveash, Corrine E., Brown, Simon H. J., Wilkins, Brendan P., Samsudeen, Azrah, Yu, Josephine, Devanapalli, Beena, Hertzog, Ashley, Tolun, Adviye A., Kavanagh, Tomas, Cooper, Antony A., Mitchell, Todd W., Biden, Trevor J., Smith, Nicola J., Cooney, Gregory J., Turner, Nigel

“…Fatty acid receptors have been recognized as important players in glycaemic control. This study is the first to describe a role for the medium‐chain fatty acid…”
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Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1 by Mouat, Margaret A, Wilkins, Brendan P, Ding, Eileen, Govindaraju, Hemna, Coleman, James L J, Graham, Robert M, Turner, Nigel, Smith, Nicola J

“…Understanding the neurogenic causes of obesity may reveal novel drug targets to counter the obesity crisis and associated sequelae. Here, we investigate…”
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Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis? by Wilkins, Brendan P., Finch, Angela M., Wang, Yan, Smith, Nicola J.

“…Atherosclerosis predisposes to myriad cardiovascular complications, including myocardial infarction and stroke. Statins have revolutionised cholesterol…”
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Orphan receptor GPR37L1 remains unliganded by Ngo, Tony, Wilkins, Brendan P., So, Sean S., Keov, Peter, Chahal, Kirti K., Finch, Angela M., Coleman, James L. J., Kufareva, Irina, Smith, Nicola J.

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SIRT2 transgenic over‐expression does not impact lifespan in mice by Wu, Lindsay E., Fiveash, Corrine E., Bentley, Nicholas L., Kang, Myung‐Jin, Govindaraju, Hemna, Barbour, Jayne A., Wilkins, Brendan P., Hancock, Sarah E., Madawala, Romanthi, Das, Abhijit, Massudi, Hassina, Li, Catherine, Kim, Lynn‐Jee, Wong, Ashley S. A., Marinova, Maria B., Sultani, Ghazal, Das, Abhirup, Youngson, Neil A., Le Couteur, David G., Sinclair, David A., Turner, Nigel

“…The NAD+‐dependent deacylase family of sirtuin enzymes have been implicated in biological ageing, late‐life health and overall lifespan, though of these…”
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Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells by Liu, Menghan, Hancock, Sarah E, Sultani, Ghazal, Wilkins, Brendan P, Ding, Eileen, Osborne, Brenna, Quek, Lake-Ee, Turner, Nigel

“…The zinc finger transcription factor Snail is a known effector of epithelial-to-mesenchymal transition (EMT), a process that underlies the enhanced…”
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