Search Results - "Wilkerson, Julia R"

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95 by Tsai, Nien-Pei, Wilkerson, Julia R., Guo, Weirui, Maksimova, Marina A., DeMartino, George N., Cowan, Christopher W., Huber, Kimberly M.

“…The activity-dependent transcription factor myocyte enhancer factor 2 (MEF2) induces excitatory synapse elimination in mouse neurons, which requires fragile X…”
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Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression by Niere, Farr, Wilkerson, Julia R, Huber, Kimberly M

“…Group 1 metabotropic glutamate receptor (mGluR)-stimulated protein synthesis and long-term synaptic depression (mGluR-LTD) are altered in the mouse model of…”
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FMRP phosphorylation and interactions with Cdh1 regulate association with dendritic RNA granules and MEF2-triggered synapse elimination by Wilkerson, Julia R., Ifrim, Marius F., Valdez-Sinon, Arielle N., Hahn, Patricia, Bowles, Jacob E., Molinaro, Gemma, Janusz-Kaminska, Aleksandra, Bassell, Gary J., Huber, Kimberly M.

“…Fragile X Messenger Ribonucleoprotein (FMRP) is necessary for experience-dependent, developmental synapse elimination and the loss of this process may underlie…”
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Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2 by Pfeiffer, Brad E., Zang, Tong, Wilkerson, Julia R., Taniguchi, Makoto, Maksimova, Marina A., Smith, Laura N., Cowan, Christopher W., Huber, Kimberly M.

“…Fragile X syndrome (FXS), the most common genetic form of mental retardation and autism, is caused by loss-of-function mutations in an RNA-binding protein,…”
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A Role for Dendritic mGluR5-Mediated Local Translation of Arc/Arg3.1 in MEF2-Dependent Synapse Elimination by Wilkerson, Julia R., Tsai, Nien-Pei, Maksimova, Marina A., Wu, Hao, Cabalo, Nicole P., Loerwald, Kristofer W., Dictenberg, Jason B., Gibson, Jay R., Huber, Kimberly M.

“…Experience refines synaptic connectivity through neural activity-dependent regulation of transcription factors. Although activity-dependent regulation of…”
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Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D by Chang, Chia-Wei, Wilkerson, Julia R, Hale, Carly F, Gibson, Jay R, Huber, Kimberly M

“…Experience and activity refine cortical circuits through synapse elimination, but little is known about the activity patterns and downstream molecular…”
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Okadaic Acid-Sensitive Protein Phosphatases Constrain Phrenic Long-Term Facilitation after Sustained Hypoxia by Wilkerson, Julia E. R, Satriotomo, Irawan, Baker-Herman, Tracy L, Watters, Jyoti J, Mitchell, Gordon S

“…Phrenic long-term facilitation (pLTF) is a serotonin-dependent form of pattern-sensitive respiratory plasticity induced by intermittent hypoxia (IH), but not…”
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Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease by Wilkerson, Julia R., Albanesi, Joseph P., Huber, Kimberly M.

“…•MGluR1/5-induced dendritic synthesis of Arc causes LTD and synapse elimination.•Arc stimulates endocytosis of postsynaptic AMPA receptors and dynamin…”
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FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination by Tsai, Nien-Pei, Wilkerson, Julia R, Guo, Weirui, Huber, Kimberly M

“…The Myocyte Enhancer Factor 2 (MEF2) transcription factors suppress an excitatory synapse number by promoting degradation of the synaptic scaffold protein,…”
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Daily intermittent hypoxia augments spinal BDNF levels, ERK phosphorylation and respiratory long-term facilitation by Wilkerson, Julia E.R., Mitchell, Gordon S.

“…Acute intermittent hypoxia (AIH) elicits a form of respiratory plasticity known as long-term facilitation (LTF). We hypothesized that: 1) daily AIH (dAIH)…”
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WWC2 modulates GABAA-receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins by Dunham, Thomas L., Wilkerson, Julia R., Johnson, Richard C., Huganir, Richard L., Volk, Lenora J.

“…The WW and C2 domain-containing protein (WWC2) is implicated in several neurological disorders. Here, we demonstrate that WWC2 interacts with inhibitory, but…”
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Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression by Barylko, Barbara, Wilkerson, Julia R, Cavalier, Sheridan H, Binns, Derk D, James, Nicholas G, Jameson, David M, Huber, Kimberly M, Albanesi, Joseph P

“…Activity-regulated cytoskeletal-associated protein (Arc, also known as activity-regulated gene 3.1 or Arg3.1) is induced in neurons in response to salient…”
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Repetitive intermittent hypoxia induces respiratory and somatic motor recovery after chronic cervical spinal injury by Lovett-Barr, Mary R, Satriotomo, Irawan, Muir, Gillian D, Wilkerson, Julia E R, Hoffman, Michael S, Vinit, Stéphane, Mitchell, Gordon S

“…Spinal injury disrupts connections between the brain and spinal cord, causing life-long paralysis. Most spinal injuries are incomplete, leaving spared neural…”
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5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems by Bartman, Michelle E, Wilkerson, Julia E.R, Johnson, Stephen M

“…Abstract To determine the role of central serotonin 5-HT3 receptors in respiratory motor control, respiratory motor bursts were recorded from hypoglossal (XII)…”
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Intermittent but not sustained moderate hypoxia elicits long-term facilitation of hypoglossal motor output by Wilkerson, Julia E.R., Devinney, Michael, Mitchell, Gordon S.

“…•Long-term facilitation of hypoglossal motor output induced by moderate hypoxia is pattern-sensitive.•Intermittent, but not sustained, moderate hypoxia,…”
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Role of synaptic inhibition in turtle respiratory rhythm generation by Johnson, Stephen M., Wilkerson, Julia E. R., Wenninger, Michael R., Henderson, Daniel R., Mitchell, Gordon S.

“…In vitro brainstem and brainstem-spinal cord preparations were used to determine the role of synaptic inhibition in respiratory rhythm generation in adult…”
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Serotonin elicits long-lasting enhancement of rhythmic respiratory activity in turtle brain stems in vitro by Johnson, Stephen M, Wilkerson, Julia E. R, Henderson, Daniel R, Wenninger, Michael R, Mitchell, Gordon S

“…Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706 Brain stem preparations from adult…”
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WWC2 modulates GABA A -receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins by Dunham, Thomas L, Wilkerson, Julia R, Johnson, Richard C, Huganir, Richard L, Volk, Lenora J

“…The WW and C2 domain-containing protein (WWC2) is implicated in several neurological disorders. Here, we demonstrate that WWC2 interacts with inhibitory, but…”
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5-HT sub(3) receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems by Bartman, Michelle E, Wilkerson, Julia ER, Johnson, Stephen M

“…To determine the role of central serotonin 5-HT sub(3) receptors in respiratory motor control, respiratory motor bursts were recorded from hypoglossal (XII)…”
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Serotonin receptor activation is necessary for phrenic long‐term facilitation following sustained hypoxia with spinal protein phosphatase inhibition by Wilkerson, Julia ER, Mitchell, Gordon S

“…Phrenic long‐term facilitation (pLTF) is a form of pattern‐sensitive respiratory plasticity elicited by intermittent (IH), but not sustained hypoxia (SH)…”
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