Search Results - "Wilke, Georgia"

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus α-hemolysin-mediated cellular injury by Wilke, Georgia A, Wardenburg, Juliane Bubeck

“…Staphylococcus aureus α-hemolysin (Hla), a potent cytotoxin, plays an important role in the pathogenesis of staphylococcal diseases, including those caused by…”
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Complement regulation in the eye: implications for age-related macular degeneration by Wilke, Georgia A, Apte, Rajendra S

“…Careful regulation of the complement system is critical for enabling complement proteins to titrate immune defense while also preventing collateral tissue…”
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A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice by Inoshima, Ichiro, Inoshima, Naoko, Wilke, Georgia A, Powers, Michael E, Frank, Karen M, Wang, Yang, Wardenburg, Juliane Bubeck

“…Staphylococcus aureus produces pore-forming toxins, such as α-hemolysin, that damage epithelial cell layers, causing disease. In this issue, Inoshima et al …”
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New-Onset Macular Schisis in a Patient With Glaucoma by Wilke, Georgia A, O'Bryhim, Bliss E, Apte, Rajendra S

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Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth by Funkhouser-Jones, Lisa J., Xu, Rui, Wilke, Georgia, Fu, Yong, Schriefer, Lawrence A., Makimaa, Heyde, Rodgers, Rachel, Kennedy, Elizabeth A., VanDussen, Kelli L., Stappenbeck, Thaddeus S., Baldridge, Megan T., Sibley, L. David

“…Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. To explore microbial influences on…”
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Peripheral Retinal Haemorrhages in a Patient with MOG-Associated Optic Neuritis by Wilke, Georgia A, Spencer, Madeline, Gilman, Carley A, Guerriero, Rejean, Bohm, Parker, Van Stavern, Gregory P, Lee, Andrew R

“…A 15-year-old female presented with headaches and bilateral vision loss. Fundoscopic examination revealed bilateral optic nerve oedema as well as peripheral…”
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Persistent reversal of enhanced amphetamine intake by transient CaMKII inhibition by Loweth, Jessica A, Li, Dongdong, Cortright, James J, Wilke, Georgia, Jeyifous, Okunola, Neve, Rachael L, Bayer, K Ulrich, Vezina, Paul

“…Amphetamine exposure transiently increases Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) α expression in the nucleus accumbens (NAcc) shell and this…”
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Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections by Russler-Germain, Emilie V., Jung, Jisun, Miller, Aidan T., Young, Shannon, Yi, Jaeu, Wehmeier, Alec, Fox, Lindsey E., Monte, Kristen J., Chai, Jiani N., Kulkarni, Devesha H., Funkhouser-Jones, Lisa J., Wilke, Georgia, Durai, Vivek, Zinselmeyer, Bernd H., Czepielewski, Rafael S., Greco, Suellen, Murphy, Kenneth M., Newberry, Rodney D., Sibley, L. David, Hsieh, Chyi-Song

“…Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of…”
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Development of an in vitro Culture System for Cryptosporidium parvum by Wilke, Georgia

“…Cryptosporidium is a genus of protozoan parasites that causes diarrheal disease in humans and other animals. There are two major species that cause disease in…”
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Development of an improved in vitro culture system for Cryptosporidium parvum by Wilke, Georgia, Funkhouser‐Jones, Lisa, Ravindran, Soumya, Kuhlenschmidt, Mark, Stappenbeck, Thad, Sibley, L. David

“…Abstract only The protozoan parasite Cryptosporidium parvum is a leading cause of pediatric diarrhea in developing countries, yet effective treatments for the…”
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Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and restricts other infections by Russler-Germain, Emilie V., Jung, Jisun, Miller, Aidan T., Young, Shannon, Yi, Jaeu, Wehmeier, Alec, Fox, Lindsey E., Monte, Kristen J., Chai, Jiani N., Kulkarni, Devesha H., Funkhouser-Jones, Lisa J., Wilke, Georgia, Durai, Vivek, Zinselmeyer, Bernd H., Czepielewski, Rafael S., Greco, Suellen, Murphy, Kenneth M., Newberry, Rodney D., Sibley, L. David, Hsieh, Chyi-Song

“…Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of…”
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A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability by Wilke, Georgia, Funkhouser-Jones, Lisa J., Wang, Yi, Ravindran, Soumya, Wang, Qiuling, Beatty, Wandy L., Baldridge, Megan T., VanDussen, Kelli L., Shen, Bang, Kuhlenschmidt, Mark S., Kuhlenschmidt, Theresa B., Witola, William H., Stappenbeck, Thaddeus S., Sibley, L. David

“…Despite being a frequent cause of severe diarrheal disease in infants and an opportunistic infection in immunocompromised patients, Cryptosporidium research…”
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Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus [alpha]-hemolysin-mediated cellular injury by Wilke, Georgia A, Wardenburg, Juliane Bubeck

“…Staphylococcus aureus α-hemolysin (Hla), a potent cytotoxin, plays an important role in the pathogenesis of staphylococcal diseases, including those caused by…”
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Transient overexpression of alpha-Ca2+/calmodulin-dependent protein kinase II in the nucleus accumbens shell enhances behavioral responding to amphetamine by Loweth, Jessica A, Singer, Bryan F, Baker, Lorinda K, Wilke, Georgia, Inamine, Hidetoshi, Bubula, Nancy, Alexander, John K, Carlezon, Jr, William A, Neve, Rachael L, Vezina, Paul

“…Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is known to contribute to the expression of psychostimulant sensitization by regulating dopamine (DA)…”
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Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression In Vitro by Wilke, Georgia, Ravindran, Soumya, Funkhouser-Jones, Lisa, Barks, Jennifer, Wang, Qiuling, VanDussen, Kelli L, Stappenbeck, Thaddeus S, Kuhlenschmidt, Theresa B, Kuhlenschmidt, Mark S, Sibley, L David

“…Among the obstacles hindering research is the lack of an culture system that supports complete life development and propagation. This major barrier has led to…”
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A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection by Inoshima, Ichiro, Inoshima, Naoko, Wilke, Georgia, Powers, Michael, Frank, Karen, Wang, Yang, Wardenburg, Juliane Bubeck

“…Staphylococcus aureus is a major cause of human disease, responsible for half a million infections and approximately 20,000 deaths per year in the United…”
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Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression italic toggle="yes">In Vitro /italic by Georgia Wilke, Soumya Ravindran, Lisa Funkhouser-Jones, Jennifer Barks, Qiuling Wang, Kelli L. VanDussen, Thaddeus S. Stappenbeck, Theresa B. Kuhlenschmidt, Mark S. Kuhlenschmidt, L. David Sibley

“…ABSTRACT Among the obstacles hindering Cryptosporidium research is the lack of an in vitro culture system that supports complete life development and…”
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Transient Overexpression of α-Ca 2+ /Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell Enhances Behavioral Responding to Amphetamine by Loweth, Jessica A., Singer, Bryan F., Baker, Lorinda K., Wilke, Georgia, Inamine, Hidetoshi, Bubula, Nancy, Alexander, John K., Carlezon, William A., Neve, Rachael L., Vezina, Paul

“…Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) is known to contribute to the expression of psychostimulant sensitization by regulating dopamine (DA)…”
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Peripheral Retinal Haemorrhages in a Patient with MOG-Associated Optic Neuritis by Wilke, Georgia A, Spencer, Madeline, Gilman, Carley A, Guerriero, Rejean, Bohm, Parker, Van Stavern, Gregory P, Lee, Andrew R

“…A 15-year-old female presented with headaches and bilateral vision loss. Fundoscopic examination revealed bilateral optic nerve oedema as well as peripheral…”
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Transient Overexpression of {alpha}-Ca2+/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell Enhances Behavioral Responding to Amphetamine by Loweth, Jessica A, Singer, Bryan F, Baker, Lorinda K, Wilke, Georgia, Inamine, Hidetoshi, Bubula, Nancy, Alexander, John K, Carlezon, William A., Jr, Neve, Rachael L, Vezina, Paul

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