Search Results - "Wilhelm, Stefan"
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Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Published in Advanced drug delivery reviews (15-03-2019)“…Nanoparticle-based therapeutics and diagnostics are commonly referred to as nanomedicine and may significantly impact the future of healthcare. However, the…”
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Nanoparticle Toxicology
Published in Annual review of pharmacology and toxicology (06-01-2021)“…Nanoparticles from natural and anthropogenic sources are abundant in the environment, thus human exposure to nanoparticles is inevitable. Due to this constant…”
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Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumors
Published in ACS nano (28-08-2018)“…Coating the nanoparticle surface with cancer cell recognizing ligands is expected to facilitate specific delivery of nanoparticles to diseased cells in vivo…”
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Bioimaging with Upconversion Nanoparticles
Published in Advanced photonics research (01-12-2022)“…Bioimaging enables the spatiotemporal visualization of biological processes at various scales empowered by a range of different imaging modalities and contrast…”
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Relative efficacy of lasmiditan versus rimegepant and ubrogepant as acute treatments for migraine: network meta-analysis findings
Published in Journal of headache and pain (01-12-2022)“…Background In the absence of head-to-head trials, comprehensive evidence comparing onset of efficacy of novel agents for acute treatment of migraine is…”
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Optical Sensing of the Ionic Strength Using Photonic Crystals in a Hydrogel Matrix
Published in ACS applied materials & interfaces (09-01-2013)“…Monodisperse, highly negatively charged, cross-linked polystyrene nanoparticles with diameters between 80 and 120 nm have been incorporated into a…”
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Short and long-term safety outcomes with ixekizumab from 7 clinical trials in psoriasis: Etanercept comparisons and integrated data
Published in Journal of the American Academy of Dermatology (01-03-2017)“…Background Safety of biologics is important when treating patients with psoriasis. Objective We sought to determine the safety of ixekizumab in psoriasis…”
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Three-Dimensional Imaging of Transparent Tissues via Metal Nanoparticle Labeling
Published in Journal of the American Chemical Society (26-07-2017)“…Chemical probes are key components of the bioimaging toolbox, as they label biomolecules in cells and tissues. The new challenge in bioimaging is to design…”
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Life-Cycle Assessment of a Multi-Megawatt Airborne Wind Energy System
Published in Energies (Basel) (01-02-2023)“…A key motivation for airborne wind energy is its potential to reduce the amount of material required for the generation of renewable energy. On the other hand,…”
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Exploring Passive Clearing for 3D Optical Imaging of Nanoparticles in Intact Tissues
Published in Bioconjugate chemistry (18-01-2017)“…The three-dimensional (3D) optical imaging of nanoparticle distribution within cells and tissues can provide insights into barriers to nanoparticle transport…”
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Label-Free Differentiation of Cancer and Non-Cancer Cells Based on Machine-Learning-Algorithm-Assisted Fast Raman Imaging
Published in Biosensors (Basel) (15-04-2022)“…This paper proposes a rapid, label-free, and non-invasive approach for identifying murine cancer cells (B16F10 melanoma cancer cells) from non-cancer cells…”
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Perspectives for Upconverting Nanoparticles
Published in ACS nano (28-11-2017)“…Upconverting nanoparticles (UCNPs) are inorganic crystalline nanomaterials that can convert near-infrared (NIR) excitation light into visible and ultraviolet…”
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Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: Data from the randomized, double-blind, COMBO-DN study
Published in Pain (Amsterdam) (01-10-2014)“…Duloxetine and pregabalin have different effects on neuropathic pain components. This might explain differential responses to these drugs when given either…”
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14
Physical Forces in Glioblastoma Migration: A Systematic Review
Published in International journal of molecular sciences (06-04-2022)“…The invasive capabilities of glioblastoma (GBM) define the cancer's aggressiveness, treatment resistance, and overall mortality. The tumor microenvironment…”
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Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells
Published in Bioactive materials (01-02-2021)“…Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment (TME) and an important contributor to cancer progression and…”
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Multicolor upconversion nanoparticles for protein conjugation
Published in Theranostics (01-01-2013)“…We describe the preparation of monodisperse, lanthanide-doped hexagonal-phase NaYF4 upconverting luminescent nanoparticles for protein conjugation. Their core…”
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Knowledge management in practice: insights into a medium-sized enterprise's exposure to knowledge loss
Published in Prometheus (Saint Lucia, Brisbane, Qld.) (01-03-2011)“…The purpose of our paper is to examine how a medium-sized enterprise characterised by slow executive turnover might identify and manage its critical knowledge…”
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Synthesis, Characterization, and Acute Cytotoxicity Evaluation of Chloroquine Encapsulating Liposomes
Published in Micro (01-03-2023)“…Liposomes encapsulating chloroquine were synthesized and characterized. Cryogenic transmission electron microscopy and dynamic light scattering confirmed a…”
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Exploring Maleimide-Based Nanoparticle Surface Engineering to Control Cellular Interactions
Published in ACS applied nano materials (27-03-2020)“…Nanoparticle cellular interactions are governed by nanoparticle surface chemistry and the surface display of functional (bio)molecules. To conjugate and…”
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Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth
Published in Advanced science (01-11-2022)“…By exploiting the self‐therapeutic properties of gold nanoparticles (GNPs) a molecular axis that promotes the growth of high‐grade serous ovarian cancer…”
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