Search Results - "Wilga, P C"

Induction of hepatic xenobiotic metabolizing enzymes in female Fischer-344 rats following repeated inhalation exposure to decamethylcyclopentasiloxane (D5) by MCKIM, J. M, CHOUDHURI, S, WILGA, P. C, MADAN, A, BURNS-NAAS, L. A, GALLAVAN, R. H, MAST, R. W, NAAS, D. J, PARKINSON, A, MEEKS, R. G

“…Decamethylcyclopentasiloxane (D5) is a cyclic siloxane with a wide range of commercial applications. The present study was designed to investigate the effects…”
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Chlorpyrifos pharmacokinetics and metabolism following intravascular and dietary administration in channel catfish by Barron, M G, Plakas, S M, Wilga, P C

“…The pharmacokinetics and metabolism of a model organophosphorothioate, chlorpyrifos, was investigated in channel catfish (Ictalurus punctatus). Chlorpyrifos…”
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Potential Estrogenic and Antiestrogenic Activity of the Cyclic Siloxane Octamethylcyclotetrasiloxane (D4) and the Linear Siloxane Hexamethyldisiloxane (HMDS) in Immature Rats Using the Uterotrophic Assay by McKim, James M., Wilga, Paul C., Breslin, William J., Plotzke, Kathy P., Gallavan, Robert H., Meeks, Robert G.

“…The cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) have numerous industrial and consumer applications…”
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Repeated Inhalation Exposure to Octamethylcyclotetrasiloxane Produces Hepatomegaly, Transient Hepatic Hyperplasia, and Sustained Hypertrophy in Female Fischer 344 Rats in a Manner Similar to Phenobarbital by McKim, James M., Kolesar, Gary B., Jean, Paul A., Meeker, Linda S., Wilga, Paul C., Schoonhoven, Robert, Swenberg, James A., Goodman, Jay I., Gallavan, Robert H., Meeks, Robert G.

“…Octamethylcyclotetrasiloxane (D4) has been described as a phenobarbital-like inducer of hepatic enzymes. Phenobarbital (PB) and phenobarbital-like chemicals…”
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Evaluation of octamethylcyclotetrasiloxane (D4) as an inducer of rat hepatic microsomal cytochrome P450, UDP-glucuronosyltransferase, and epoxide hydrolase: a 28-day inhalation study by McKim, Jr, J M, Wilga, P C, Kolesar, G B, Choudhuri, S, Madan, A, Dochterman, L W, Breen, J G, Parkinson, A, Mast, R W, Meeks, R G

“…Repeated inhalation exposure to octamethylcyclotetrasiloxane (D4) produces a reversible and dose-related hepatomegaly and proliferation of hepatic endoplasmic…”
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