Search Results - "Wilfong, Erin"

Role of antifibrotics in the management of idiopathic inflammatory myopathy associated interstitial lung disease by Wilfong, Erin M., Aggarwal, Rohit

“…The antifibrotic therapies nintedanib and pirfenidone were first approved by the United States for the treatment of idiopathic pulmonary fibrosis in 2014. In…”
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Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation by Wilfong, Erin M, Croze, Roxanne, Fang, Xiaohui, Schwede, Matthew, Niemi, Erene, López, Giselle Y, Lee, Jae-Woo, Nakamura, Mary C, Matthay, Michael A

“…Human mesenchymal stem/stromal cells (hMSCs) are a promising therapy for acute respiratory distress syndrome (ARDS) and other inflammatory conditions. While…”
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Intravenous immunoglobulin therapy for COVID-19 ARDS by Wilfong, Erin M, Matthay, Michael A

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Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine by Kramer, Kevin J., Wilfong, Erin M., Voss, Kelsey, Barone, Sierra M., Shiakolas, Andrea R., Raju, Nagarajan, Roe, Caroline E., Suryadevara, Naveenchandra, Walker, Lauren M., Wall, Steven C., Paulo, Ariana, Schaefer, Samuel, Dahunsi, Debolanle, Westlake, Camille S., Crowe, James E., Carnahan, Robert H., Rathmell, Jeffrey C., Bonami, Rachel H., Georgiev, Ivelin S., Irish, Jonathan M.

“…RNA-based vaccines against SARS-CoV-2 have proven critical to limiting COVID-19 disease severity and spread. Cellular mechanisms driving antigen-specific…”
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Multiparameter analysis of human B lymphocytes identifies heterogeneous CD19+CD21lo subsets by Wilfong, Erin M., Vowell, Katherine N., Crofford, Leslie J., Kendall, Peggy L.

“…Autoreactive B cell subsets have been described in a variety of settings, using multiple classification schemes and cell surface markers also found on healthy…”
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Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients by Young-Glazer, Jennifer, Cisneros, 3rd, Alberto, Wilfong, Erin M, Smith, Scott A, Crofford, Leslie J, Bonami, Rachel H

“…Anti-Jo-1 autoantibodies which recognize histidyl-tRNA synthetase identify patients with the rare rheumatologic disease, anti-histidyl-tRNA synthetase syndrome…”
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Multiparameter analysis of human B lymphocytes identifies heterogeneous CD19 + CD21 lo subsets by Wilfong, Erin M, Vowell, Katherine N, Crofford, Leslie J, Kendall, Peggy L

“…Autoreactive B cell subsets have been described in a variety of settings, using multiple classification schemes and cell surface markers also found on healthy…”
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Interstitial Pneumonia With Autoimmune Features: An Emerging Challenge at the Intersection of Rheumatology and Pulmonology by Wilfong, Erin M, Lentz, Robert J, Guttentag, Adam, Tolle, James J, Johnson, Joyce E, Kropski, Jonathan A, Kendall, Peggy L, Blackwell, Timothy S, Crofford, Leslie J

“…Interstitial lung disease (ILD) remains a cause of significant morbidity and mortality in patients with connective tissue disease (CTD)-associated ILD. While…”
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Anti-tRNA synthetase syndrome interstitial lung disease: A single center experience by Wilfong, Erin M., Young-Glazer, Jennifer J., Sohn, Bret K., Schroeder, Gabriel, Annapureddy, Narender, Gillaspie, Erin A., Barnado, April, Crofford, Leslie J., Dudenhofer, Rosemarie Beckford

“…Recognition of Anti-tRNA synthetase (ARS) related interstitial lung disease (ILD) is key to ensuring patients have prompt access to immunosuppressive…”
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High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies by Wilfong, Erin M, Bartkowiak, Todd, Vowell, Katherine N, Westlake, Camille S, Irish, Jonathan M, Kendall, Peggy L, Crofford, Leslie J, Bonami, Rachel H

“…The idiopathic inflammatory myopathies (IIM) are a rare clinically heterogeneous group of conditions affecting the skin, muscle, joint, and lung in various…”
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Risk factors for mortality and mortality rates in interstitial lung disease patients in the intensive care unit by Huapaya, Julio A, Wilfong, Erin M, Harden, Christopher T, Brower, Roy G, Danoff, Sonye K

“…Data on interstitial lung disease (ILD) outcomes in the intensive care unit (ICU) is of limited value due to population heterogeneity. The aim of this study…”
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High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors by Joosse, Bryan A, Jackson, James H, Cisneros, Alberto, Santhin, Austin B, Smith, Scott A, Moore, Daniel J, Crofford, Leslie J, Wilfong, Erin M, Bonami, Rachel H

“…Antigen-specific B cells (ASBCs) can drive autoimmune disease by presenting autoantigen to cognate T cells to drive their activation, proliferation, and…”
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CD19 + CD21lo/neg cells are increased in systemic sclerosis-associated interstitial lung disease by Wilfong, Erin M., Vowell, Katherine N., Bunn, Kaitlyn E., Rizzi, Elise, Annapureddy, Narender, Dudenhofer, Rosemarie B., Barnado, April, Bonami, Rachel H., Johnson, Joyce E., Crofford, Leslie J., Kendall, Peggy L.

“…Interstitial lung disease (ILD) represents a significant cause of morbidity and mortality in systemic sclerosis (SSc). The purpose of this study was to examine…”
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CD4 + T cells expressing CX3CR1, GPR56, with variable CD57 are associated with cardiometabolic diseases in persons with HIV by Wanjalla, Celestine N, Gabriel, Curtis L, Fuseini, Hubaida, Bailin, Samuel S, Mashayekhi, Mona, Simmons, Joshua, Warren, Christopher M, Glass, David R, Oakes, Jared, Gangula, Rama, Wilfong, Erin, Priest, Stephen, Temu, Tecla, Newell, Evan W, Pakala, Suman, Kalams, Spyros A, Gianella, Sara, Smith, David, Harrison, David G, Mallal, Simon A, Koethe, John R

“…Persons with HIV (PWH) on long-term antiretroviral therapy (ART) have a higher incidence and prevalence of cardiometabolic diseases attributed, in part, to…”
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Vasculitis in the intensive care unit by Wilfong, Erin M., M.D., Ph.D, Seo, Philip, M.D., MHS

“…The systemic vasculitides are a diverse set of diseases linked by the presence of blood-vessel inflammation and are often associated with life-threatening or…”
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Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease by Chioma, Ozioma S, Mallott, Elizabeth, Shah-Gandhi, Binal, Wiggins, ZaDarreyal, Langford, Madison, Lancaster, Andrew William, Gelbard, Alexander, Wu, Hongmei, Johnson, Joyce E, Lancaster, Lisa, Wilfong, Erin M, Crofford, Leslie J, Montgomery, Courtney G, Van Kaer, Luc, Bordenstein, Seth, Newcomb, Dawn C, Drake, Wonder Puryear

“…Although profibrotic cytokines, such as IL-17A and TGF-β1, have been implicated in the pathogenesis of interstitial lung disease (ILD), the interactions…”
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Interstitial Pneumonia With Autoimmune Features by Wilfong, Erin M., Lentz, Robert J., Guttentag, Adam, Tolle, James J., Johnson, Joyce E., Kropski, Jonathan A., Kendall, Peggy L., Blackwell, Timothy S., Crofford, Leslie J.

“…Interstitial lung disease (ILD) remains a cause of significant morbidity and mortality in patients with connective tissue disease (CTD)–associated ILD. While…”
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An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1 by Wilfong, Erin M., Du, Yu, Toone, Eric J.

“…Fragment based drug discovery remains a successful tool for pharmaceutical lead discovery. Although based upon the principle of thermodynamic additivity, the…”
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Effects of bone marrow‐derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF‐α, IL‐1β, and IFN‐γ by Schwede, Matthew, Wilfong, Erin M., Zemans, Rachel L., Lee, Patty J., Santos, Claudia, Fang, Xiaohui, Matthay, Michael A.

“…The acute respiratory distress syndrome (ARDS) is common in critically ill patients and has a high mortality rate. Mesenchymal stromal cells (MSCs) have…”
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A Multidisciplinary Approach to Probing Enthalpy–Entropy Compensation and the Interfacial Mobility Model by Wilfong, Erin M, Kogiso, Yuri, Muthukrishnan, Sivaramakrishnan, Kowatz, Thomas, Du, Yu, Bowie, Amber, Naismith, James H, Hadad, Christopher M, Toone, Eric J, Gustafson, Terry L

“…In recent years, interfacial mobility has gained popularity as a model with which to rationalize both affinity in ligand binding and the often observed…”
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