Search Results - "Wilffert, B."

Pharmacogenetics: From Bench to Byte- An Update of Guidelines by Swen, JJ, Nijenhuis, M, Boer, A, Grandia, L, Maitland‐van der Zee, AH, Mulder, H, Rongen, GAPJM, Schaik, RHN, Schalekamp, T, Touw, DJ, Weide, J, Wilffert, B, Deneer, VHM, Guchelaar, H‐J

“…Currently, there are very few guidelines linking the results of pharmacogenetic tests to specific therapeutic recommendations. Therefore, the Royal Dutch…”
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A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS by Berm, E.J.J., Paardekooper, J., Brummel-Mulder, E., Hak, E., Wilffert, B., Maring, J.G.

“…Therapeutic drug monitoring (TDM) of tricyclic antidepressants (TCAs) is considered useful in patients with major depressive disorder, since these drugs…”
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Relation between CYP2D6 Genotype, Phenotype and Therapeutic Drug Concentrations among Nortriptyline and Venlafaxine Users in Old Age Psychiatry by Berm, E, Kok, R, Hak, E, Wilffert, B

“…To determine relations between drug concentrations and the cytochrome P450-CYP2D6 genotype or phenotype among elderly patients treated with nortriptyline or…”
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Predictors of response in initial users of metformin and sulphonylurea derivatives: a systematic review by Martono, D. P., Lub, R., Lambers Heerspink, H. J., Hak, E., Wilffert, B., Denig, P.

“…Aim To provide an overview of factors predicting metformin and sulphonylurea treatment response. Background A large variability between individuals in…”
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Pharmacogenetics: From Bench to Byte by Swen, JJ, Wilting, I, Goede, AL, Grandia, L, Mulder, H, Touw, DJ, Boer, A, Conemans, JMH, Egberts, TCG, Klungel, OH, Koopmans, R, Weide, J, Wilffert, B, Guchelaar, H‐J, Deneer, VHM

“…Despite initial enthusiasm,1,2,3 the use of pharmacogenetics has remained limited to investigation in only a few clinical fields such as oncology and…”
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Determination of venlafaxine and O-desmethylvenlafaxine in dried blood spots for TDM purposes, using LC-MS/MS by Berm, E. J. J., Brummel-Mulder, E., Paardekooper, J., Hak, E., Wilffert, B., Maring, J. G.

“…Dried blood spot (DBS) sampling and quantitative analyses of many current therapeutic drug monitoring (TDM)-guided drugs are advantageous because of the…”
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CYP2D6 and catechol-O-methyltransferase gene polymorphisms in Parkinson patients with levodopa-induced dyskinesias by Ivanova, S.A, Alifirova, V.M, Pozhidaev, I.V, Fedorenko, O.Y, Osmanova, D.Z, Tiguntsev, V.V, Bokhan, N.A, Zhukova, I.A, Wilffert, B, Loonen, A.J.M

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Gene polymorphism of serotonin receptors and drug-induced hyperprolactinemia in schizophrenic patients by Osmanova, D.Z, Boiko, A.S, Fedorenko, O.Y, Pozhidaev, I.V, Freidin, M.B, Kornetova, E.G, Ivanova, S.A, Wilffert, B, Loonen, A.J.M

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Association between HTR2C gene polymorphisms and the metabolic syndrome in patients using antipsychotics: a replication study by Risselada, A J, Vehof, J, Bruggeman, R, Wilffert, B, Cohen, D, Al Hadithy, A F, Arends, J, Mulder, H

“…In two previous studies we found an association between HTR2C polymorphisms and the prevalence of the metabolic syndrome in patients using antipsychotics. In…”
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P.5.d.005 Polymorphisms of DRD2, DRD3, DRD4 and HTR2C genes in levodopa-induced dyskinesias in Parkinson's disease by Ivanova, S.A, Alifirova, V.M, Fedorenko, O.Y, Freidin, M.B, Bokhan, N.A, Zhukova, I, Al Hadithy, A.F.Y, Brouwers, J.R.B.J, Wilffert, B, Loonen, A.J.M

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Pharmacokinetics of clomipramine during pregnancy by ter Horst, P. G. J., Proost, J. H., Smit, J. P., Vries, M. T., de Jong-van de Berg, L. T. W., Wilffert, B.

“…Purpose Clomipramine is one of the drugs for depression during pregnancy; however, pharmacokinetic data of clomipramine and its active metabolite…”
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4-Aminopyridine as a life-saving treatment in calcium channel antagonist intoxication by van der Voort, P H J, Wilffert, B, van Roon, E N, Uges, D R A

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NMDA receptor genotypes associated with the vulnerability to develop dyskinesia by Ivanova, S A, Loonen, A J M, Pechlivanoglou, P, Freidin, M B, Al Hadithy, A F Y, Rudikov, E V, Zhukova, I A, Govorin, N V, Sorokina, V A, Fedorenko, O Y, Alifirova, V M, Semke, A V, Brouwers, J R B J, Wilffert, B

“…Dyskinesias are involuntary muscle movements that occur spontaneously in Huntington's disease (HD) and after long-term treatments for Parkinson's disease…”
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Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia by Al Hadithy, A.F.Y., Ivanova, S.A., Pechlivanoglou, P., Semke, A., Fedorenko, O., Kornetova, E., Ryadovaya, L., Brouwers, J.R.B.J., Wilffert, B., Bruggeman, R., Loonen, A.J.M.

“…Pharmacogenetics of tardive dyskinesia and dopamine D3 (DRD3), serotonin 2A (HTR2A), and 2C (HTR2C) receptors has been examined in various populations, but not…”
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P.3.a.006 Tardive dyskinesia, dehydroepiandrosterone sulfate and cytochrome P450c17α gene polymorphism in psychiatric inpatients by Ivanova, S.A, Geers, L.M, Al Hadithy, A.F.Y, Pechlivanoglou, P, Semke, A.V, Vyalova, N.M, Fedorenko, O.Y, Brouwers, J.R.B.J, Wilffert, B, Loonen, A.J.M

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Influencing CYP enzymes to boost psychiatric treatment: a review on clinical evidence by van Hasselt, F M, Coehorst, Y, Wilffert, B, Loonen, A J M

“…Therapeutic drug monitoring to optimize blood plasma concentrations is advised for certain psychiatric drugs. The current standard is to change the dose based…”
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Missense polymorphisms in three oxidative-stress enzymes (GSTP1, SOD2, and GPX1) and dyskinesias in Russian psychiatric inpatients from Siberia by Al Hadithy, A. F. Y., Ivanova, S. A., Pechlivanoglou, P., Wilffert, B., Semke, A., Fedorenko, O., Kornetova, E., Ryadovaya, L., Brouwers, J. R. B. J., Loonen, A. J. M.

“…Neuronal degeneration due to oxidative stress (OS) has been proposed as a mechanism for tardive dyskinesia (TD) pathogenesis. Cellular defense mechanisms…”
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In utero exposure to antidepressants and the use of drugs for pulmonary diseases in children by ter Horst, P. G. J., Bos, H. J., de Jong-van de Berg, L. T. W., Wilffert, B.

“…Purpose The use of antidepressants during pregnancy is common. Some studies suggest an association between in utero exposure to antidepressants and the…”
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CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers : indications for oral contraceptive-related gender differences by TAMMINGA, W. J, WEMER, J, OOSTERHUIS, B, WIELING, J, WILFFERT, B, DE LEIJ, L. F. M. H, DE ZEEUW, R. A, JONKMAN, J. H. G

“…We examined a large database containing results on CYP2D6 and CYP2C19 activity of 4301 Dutch volunteers phenotyped in the context of various clinical…”
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P.3.001 NMDA receptor co-determines vulnerability to develop dyskinesia in Huntington's Disease and levodopa-induced dyskinesia but not tardive dyskinesia by Loonen, A.J.M, Ivanova, S.A, Pechlivanoglou, P, Rudikov, E, Zhukova, I, Al Hadithy, A.F.Y, Alifirova, V, Brouwers, J.R.B.J, Semke, A, Wilffert, B

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